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High-resolution x-ray tomography is a common technique for biomedical research using synchrotron sources. With advancements in laboratory x-ray sources, an increasing number of experiments can be performed in the lab. In this paper, the…

Instrumentation and Detectors · Physics 2024-08-23 Till Dreier , Robin Krüger , Gustaf Bernström , Karin Tran-Lundmark , Isabel Gonçalves , Martin Bech

X-ray imaging, traditionally relying on attenuation contrast, struggles to differentiate materials with similar attenuation coefficients like soft tissues. X-ray phase contrast imaging (XPCI) and dark-field (DF) imaging provide enhanced…

Medical Physics · Physics 2025-06-05 Jingcheng Yuan , Mini Das

A propagation-based x-ray phase-contrast imaging (PBI) setup using a conventional x-ray source (LFF Cu target) is presented. A virtual x-ray source of 40 x 50 $\mu$$m^2$ was created by using, horizontally, a $6^o$ take-off angle (with the…

Other Condensed Matter · Physics 2007-10-08 M. G. Hönnicke , E. M. Kakuno , J. Manica , C. Cusatis

X-ray grating interferometry is an excellent technique for X-ray phase contrast imaging and X-ray wavefront sensing with applications in materials science, biology and medical diagnosis. Among other requirements, the method depends on the…

This study describes a new approach for material decomposition in x-ray imaging, utilising phase contrast to both increase sensitivity to weakly-attenuating samples and to act as a complementary measurement to attenuation, therefore…

X-ray ptychography has revolutionised nanoscale phase contrast imaging at large-scale synchrotron sources in recent years. We present here the first successful demonstration of the technique in a small-scale laboratory setting. We conducted…

Recently, X-ray interferometers with more than one phase grating have been developed for differential phase contrast (DPC) imaging. In this study, a novel framework is developed to predict such interferometers' angular sensitivity responses…

Instrumentation and Detectors · Physics 2020-06-25 Jianwei Chen , Jiecheng Yang , Peiping Zhu , Ting Su , Huitao Zhang , Hairong Zheng , Dong Liang , Yongshuai Ge

As a multi-contrast X-ray computed tomography (CT) imaging system, the grating-based Talbot-Lau interferometer is able to generate the absorption contrast and differential phase contrast (DPC) images concurrently. However, experiments found…

Medical Physics · Physics 2024-04-16 Yuhang Tan , Jiecheng Yang , Hairong Zheng , Dong Liang , Peiping Zhu , Yongshuai Ge

X-ray phase-contrast imaging has the potential to improve image contrast with lower dose by probing an object's refractive properties as well as its absorptive properties. To reconstruct a phase-contrast image from a raw dataset, a phase…

Medical Physics · Physics 2025-08-19 Giavanna Jadick , Patrick La Rivière

Diffractive optical elements such as periodic gratings are fundamental devices in X-ray imaging - a technique that medical, material science and security scans rely upon. Fabrication of such structures with high aspect ratios at the…

These tutorials introduce some basics of imaging with coherent X-rays, focusing on phase contrast. We consider the transport-of-intensity equation, as one particular method for X-ray phase contrast imaging among many, before passing on to…

Image and Video Processing · Electrical Eng. & Systems 2019-02-28 David M. Paganin , Daniele Pelliccia

We previously demonstrated near-field speckle scanning based x-ray imaging to be an easy-to-implement phase sensing method capable of providing both high sensitivity and high resolution. Yet, this performance combination could only be…

Medical Physics · Physics 2017-06-21 Sebastien Berujon , Eric Ziegler

X-ray phase-contrast imaging has recently led to a revolution in resolving power and tissue contrast in biomedical imaging, microscopy and materials science. The necessary high spatial coherence is currently provided by either large-scale…

Plasma Physics · Physics 2019-06-26 J. Wenz , S. Schleede , K. Khrennikov , M. Bech , P. Thibault , M. Heigoldt , F. Pfeiffer , S. Karsch

Material decomposition in X-ray imaging uses the energy-dependence of attenuation to virtually decompose an object into specific constituent materials. X-ray phase contrast imaging is a developing technique that can enhance image contrast…

Two-dimensional Talbot array illuminators (TAIs) were designed, fabricated, and evaluated for high-resolution high-contrast x-ray phase imaging of soft tissue at 10-20keV. The TAIs create intensity modulations with a high compression ratio…

We outline some basics of imaging using both fully-coherent and partially-coherent X-ray beams, with an emphasis on phase-contrast imaging. We open with some of the basic notions of X-ray imaging, including the vacuum wave equations and the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 David M. Paganin , Daniele Pelliccia

X-ray Talbot-Lau interferometer has been used widely to conduct phase contrast imaging with a conventional low-brilliance x-ray source. Typically, in this technique, background correction has to be performed in order to obtain the pure…

X-ray microtomography is a versatile tool allowing the measurement of the 3D structure of optically thick samples. As a non-destructive technique, it is readily adapted to 4D imaging, where a sample can be monitored over time, and…

Instrumentation and Detectors · Physics 2025-12-17 Harry Allan , Tom Partridge , Joseph Jacob , Marco Endrizzi

Grating interferometer is a state of art x-ray imaging approach, which can simultaneously acquire information of x-ray attenuation, phase shift, and small angle scattering. This approach is very sensitive to micro-structural variation and…

Medical Physics · Physics 2015-09-21 Wenxiang Cong , Yan Xi , Ge Wang

Quantum imaging employs the nonclassical correlation of photons to break through the noise limitation of classical imaging, realizing high sensitivity, high SNR imaging and multifunctional image processing. To enhance the flexibility and…