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Gynecologic malignancies are a leading cause of death in women worldwide. Standard treatment for many primary and recurrent gynecologic cancer cases includes a combination of external beam radiation, followed by brachytherapy. Magnetic…

Medical Physics · Physics 2017-08-24 Tina Kapur , Jan Egger , Antonio Damato , Ehud J. Schmidt , Akila N. Viswanathan

German text, english abstract: Mortality in gynecologic cancers, including cervical, ovarian, vaginal and vulvar cancers, is more than 6% internationally [1]. In many countries external radiotherapy is supplemented by brachytherapy with…

Medical Physics · Physics 2018-03-13 Andre Mastmeyer

In this contribution, an image-guided therapy system supporting gynecologic radiation therapy is introduced. The overall workflow of the presented system starts with the arrival of the patient and ends with follow-up examinations by imaging…

Computational Engineering, Finance, and Science · Computer Science 2013-09-24 Jan Egger

Among all types of cancer, gynecological malignancies belong to the 4th most frequent type of cancer among women. Besides chemotherapy and external beam radiation, brachytherapy is the standard procedure for the treatment of these…

Computer Vision and Pattern Recognition · Computer Science 2016-08-24 Tobias Lüddemann , Jan Egger

Biopsy is commonly used to confirm cancer diagnosis when radiologically indicated. Given the ability of PET to localize malignancies in heterogeneous tumors and tumors that do not have a CT correlate, PET/CT guided biopsy may improve the…

Volumetric change in glioblastoma multiforme (GBM) over time is a critical factor in treatment decisions. Typically, the tumor volume is computed on a slice-by-slice basis using MRI scans obtained at regular intervals. (3D)Slicer - a free…

Computer Vision and Pattern Recognition · Computer Science 2013-03-06 Jan Egger , Tina Kapur , Andriy Fedorov , Steve Pieper , James V. Miller , Harini Veeraraghavan , Bernd Freisleben , Alexandra Golby , Christopher Nimsky , Ron Kikinis

Poor adaptation of orbital implants remains a major contributor to postoperative complications and revision surgery. Although preformed orbital plates are widely used to reduce cost and operative time compared with customized implants,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Chi Zhang , Braedon Gunn , Andrew M. Read-Fuller

Image-guided robotic interventions involve the use of medical imaging in tandem with robotics. SlicerROS2 is a software module that combines 3D Slicer and robot operating system (ROS) in pursuit of a standard integration approach for…

High dose-rate brachytherapy (HDRBT) is widely used for gynecological cancer treatment. Although commercial treatment planning systems (TPSs) have inverse optimization modules, it takes several iterations to adjust planning objectives to…

Medical Physics · Physics 2021-09-14 Huan Liu , Chang M Ma , Xun Jia , Chenyang Shen , Peter Klages , Kevin Albuquerque

Image-guided robotic interventions represent a transformative frontier in surgery, blending advanced imaging and robotics for improved precision and outcomes. This paper addresses the critical need for integrating open-source platforms to…

Robot-assisted Transcranial Magnetic Stimulation (Robo-TMS) is an image-guided robotic intervention that enhances the accuracy and reproducibility of conventional Transcranial Magnetic Stimulation (TMS), a widely used non-invasive brain…

Robotics · Computer Science 2026-04-29 Wenzhi Bai , Yituo Guo , Bhaskar Basu , Andrew Weightman , Zhenhong Li

Upcoming HI surveys will deliver such large datasets that automated processing using the full 3-D information to find and characterize HI objects is unavoidable. Full 3-D visualization is an essential tool for enabling qualitative and…

Instrumentation and Methods for Astrophysics · Physics 2017-06-14 J. M. van der Hulst , D. Punzo , J. B. T. M. Roerdink

The AstroMed project at Harvard University's Initiative in Innovative Computing (IIC) is working on improved visualization and data sharing solutions applicable to the fields of both astronomy and medicine. The current focus is on the…

Astrophysics · Physics 2007-05-23 Michelle Borkin , Alyssa Goodman , Michael Halle , Douglas Alan

Brachytherapy for localized prostate cancer consists in destroying cancer by introducing iodine radioactive seeds into the gland through hollow needles. The planning of the position of the seeds and their introduction into the prostate is…

Prostate brachytherapy involves implanting radioactive seeds (I125 for instance) permanently in the gland for the treatment of localized prostate cancers, e.g., cT1c-T2a N0 M0 with good prognostic factors. Treatment planning and seed…

Cervical cancer presents a significant global health challenge, necessitating advanced diagnostic and prognostic approaches for effective treatment. This paper investigates the potential of employing multi-modal medical imaging at various…

Medical Physics · Physics 2024-08-27 Haotian Feng , Emi Yoshida , Ke Sheng

Surgical treatment for prostate cancer often involves organ removal, i.e., prostatectomy. Pathology reports on these specimens convey treatment-relevant information. Beyond these reports, the diagnostic process generates extensive and…

Volumetric measurements are known to provide more information when it comes to segmenting tumors, in comparison to one- and two-dimensional measurements, and thus can lead to better informed therapy. In this work, we review the free and…

Quantitative Methods · Quantitative Biology 2020-09-01 Marina Kazarian , Sandra Abi Fadel , Amit Mahajan , Mariam Aboian

Clinicians benefit from online treatment planning systems, through off-site accessibility, data sharing and professional interaction. As well as enhancing clinical value, incorporation of simulation tools affords innovative avenues for…

In this study, we present pituitary adenoma volumetry using the free and open source medical image computing platform for biomedical research: (3D) Slicer. Volumetric changes in cerebral pathologies like pituitary adenomas are a critical…

Computer Vision and Pattern Recognition · Computer Science 2012-12-13 Jan Egger , Tina Kapur , Christopher Nimsky , Ron Kikinis
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