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Related papers: A Logical Framework for Systems Biology

200 papers

We advocates here the use of (mathematical) logic for systems biology, as a unified framework well suited for both modeling the dynamic behaviour of biological systems, expressing properties of them, and verifying these properties. The…

Logic in Computer Science · Computer Science 2017-01-19 Joëlle Despeyroux

For performance and verification in machine learning, new methods have recently been proposed that optimise learning systems to satisfy formally expressed logical properties. Among these methods, differentiable logics (DLs) are used to…

Logic in Computer Science · Computer Science 2024-07-08 Reynald Affeldt , Alessandro Bruni , Ekaterina Komendantskaya , Natalia Ślusarz , Kathrin Stark

We advocate here the use of computational logic for systems biology, as a \emph{unified and safe} framework well suited for both modeling the dynamic behaviour of biological systems, expressing properties of them, and verifying these…

Quantitative Methods · Quantitative Biology 2020-10-07 Elisabetta de Maria , Joelle Despeyroux , Amy Felty , Pietro Liò , Carlos Olarte , Abdorrahim Bahrami

Matching logic is a formalism for specifying, and reasoning about, mathematical structures, using patterns and pattern matching. Growing in popularity, it has been used to define many logical systems such as separation logic with recursive…

Logic in Computer Science · Computer Science 2022-09-22 Péter Bereczky , Xiaohong Chen , Dániel Horpácsi , Lucas Peña , Jan Tušil

We axiomatize the molecular-biology reasoning style, show compliance of the standard reference: Ptashne, A Genetic Switch, and present proof-theory-induced technologies to help infer phenotypes and to predict life cycles from genotypes. The…

Other Quantitative Biology · Quantitative Biology 2019-03-19 René Vestergaard , Emmanuel Pietriga

This article introduces a fully automated verification technique that permits to analyze real-time systems described using a continuous notion of time and a mixture of operational (i.e., automata-based) and descriptive (i.e., logic-based)…

Logic in Computer Science · Computer Science 2013-08-14 Carlo A. Furia , Matteo Pradella , Matteo Rossi

Although they differ in the functionality they offer, low-level systems exhibit certain patterns of design and utilization of computing resources. In this paper, we argue the position that modalities, in the sense of modal logic, should be…

Logic in Computer Science · Computer Science 2025-09-30 Ismail Kuru , Colin S. Gordon

Current approaches for formal verification of algorithms face important limitations. For specification, they cannot express algorithms naturally and concisely, especially for algorithms with states and flexible control flow. For…

Programming Languages · Computer Science 2025-05-01 Chengxi Yang , Shushu Wu , Qinxiang Cao

We introduce a framework for reasoning about the security of computer systems using modal logic. This framework is sufficiently expressive to capture a variety of known security properties, while also being intuitive and independent of…

Cryptography and Security · Computer Science 2023-09-19 Matvey Soloviev , Musard Balliu , Roberto Guanciale

We present a method for logical specification of the behavior of a system based on the specification of its components and for representing and specifying the effect of a class of communication "signaling pathways" among them. Variations in…

Other Quantitative Biology · Quantitative Biology 2019-09-09 Leo Marcus

We introduce a machine learning approach to model checking temporal logic, with application to formal hardware verification. Model checking answers the question of whether every execution of a given system satisfies a desired temporal logic…

Logic in Computer Science · Computer Science 2024-11-01 Mirco Giacobbe , Daniel Kroening , Abhinandan Pal , Michael Tautschnig

Verification of temporal logic properties plays a crucial role in proving the desired behaviors of continuous systems. In this paper, we propose an interval method that verifies the properties described by a bounded signal temporal logic.…

Logic in Computer Science · Computer Science 2016-02-09 Daisuke Ishii , Naoki Yonezaki , Alexandre Goldsztejn

Precisely modeling complex systems like cyber-physical systems is challenging, which often render model-based system verification techniques like model checking infeasible. To overcome this challenge, we propose a method called LAR to…

Software Engineering · Computer Science 2019-11-21 Jingyi Wang , Jun Sun , Shengchao Qin , Cyrille Jegourel

We propose a verified approach to the formal verification of timed properties using model-checking techniques. We focus on properties expressed using real-time specification patterns, which can be viewed as a subset of timed temporal logics…

Logic in Computer Science · Computer Science 2013-02-01 Nouha Abid , Silvano Dal Zilio , Didier Le Botlan

Complex systems typically have many different parts and facets, with different characteristics. In a multi-paradigm approach to modeling, formalisms with different natures are used in combination to describe complementary parts and aspects…

Logic in Computer Science · Computer Science 2013-08-14 Marcello M. Bersani , Carlo A. Furia , Matteo Pradella , Matteo Rossi

The work concerns formal verification of workflow-oriented software models using deductive approach. The formal correctness of a model's behaviour is considered. Manually building logical specifications, which are considered as a set of…

Software Engineering · Computer Science 2015-01-05 Radoslaw Klimek

A rigorous formalization of desired system requirements is indispensable when performing any verification task. This often limits the application of verification techniques, as writing formal specifications is an error-prone and…

Logic in Computer Science · Computer Science 2023-03-10 Matthias Cosler , Christopher Hahn , Daniel Mendoza , Frederik Schmitt , Caroline Trippel

Synchronous model is a type of formal models for modelling and specifying reactive systems. It has a great advantage over other real-time models that its modelling paradigm supports a deterministic concurrent behaviour of systems. Various…

Software Engineering · Computer Science 2021-04-09 Yuanrui Zhang

We present a first-order linear-time temporal logic for reasoning about the evolution of directed graphs. Its semantics is based on the counterpart paradigm, thus allowing our logic to represent the creation, duplication, merging, and…

Logic in Computer Science · Computer Science 2023-05-09 Fabio Gadducci , Andrea Laretto , Davide Trotta

Large Language Models (LLMs) show remarkable capabilities, yet their stochastic next-token prediction creates logical inconsistencies and reward hacking that formal symbolic systems avoid. To bridge this gap, we introduce a formal logic…

Machine Learning · Computer Science 2026-02-02 Chuxue Cao , Jinluan Yang , Haoran Li , Kunhao Pan , Zijian Zhao , Zhengyu Chen , Yuchen Tian , Lijun Wu , Conghui He , Sirui Han , Yike Guo
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