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Reconstructing multiple molecularly defined neurons from individual brains and across multiple brain regions can reveal organizational principles of the nervous system. However, high resolution imaging of the whole brain is a technically…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 James Gornet , Kannan Umadevi Venkataraju , Arun Narasimhan , Nicholas Turner , Kisuk Lee , H. Sebastian Seung , Pavel Osten , Uygar Sümbül

Brain connectomics is a developing field in neurosciences which strives to understand cognitive processes and psychiatric diseases through the analysis of interactions between brain regions. However, in the high-dimensional, low-sample, and…

Applications · Statistics 2019-11-15 Claire Donnat , Leonardo Tozzi , Susan Holmes

Neuroimaging-based prediction methods for intelligence and cognitive abilities have seen a rapid development in literature. Among different neuroimaging modalities, prediction based on functional connectivity (FC) has shown great promise.…

Neurons and Cognition · Quantitative Biology 2023-07-20 Yang Li , Xin Ma , Raj Sunderraman , Shihao Ji , Suprateek Kundu

An unprecedented amount of existing functional Magnetic Resonance Imaging (fMRI) data provides a new opportunity to understand the relationship between functional fluctuation and human cognition/behavior using a data-driven approach. To…

Machine Learning · Computer Science 2024-09-18 Jiaqi Ding , Tingting Dan , Ziquan Wei , Hyuna Cho , Paul J. Laurienti , Won Hwa Kim , Guorong Wu

Gaining insights into the structural and functional mechanisms of the brain has been a longstanding focus in neuroscience research, particularly in the context of understanding and treating neuropsychiatric disorders such as Schizophrenia…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Badhan Mazumder , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Accurate segmentation and classification of brain tumors from Magnetic Resonance Imaging (MRI) remain key challenges in medical image analysis, primarily due to the lack of high-quality, balanced, and diverse datasets with expert…

Image and Video Processing · Electrical Eng. & Systems 2026-01-29 Amirreza Fateh , Yasin Rezvani , Sara Moayedi , Sadjad Rezvani , Fatemeh Fateh , Mansoor Fateh , Vahid Abolghasemi

While the machine learning literature dedicated to fully automated reasoning algorithms is abundant, the number of methods enabling the inference process on the basis of previously defined knowledge structures is scanter. Fuzzy Cognitive…

Machine Learning · Computer Science 2018-09-24 Gonzalo Nápoles , Frank Vanhoenshoven , Koen Vanhoof

In this study, a radiomics approach was extended to optical fluorescence molecular imaging data for tissue classification, termed 'optomics'. Fluorescence molecular imaging is emerging for precise surgical guidance during head and neck…

We introduce FENNIX (Force-Field-Enhanced Neural Network InteraXions), a hybrid approach between machine-learning and force-fields. We leverage state-of-the-art equivariant neural networks to predict local energy contributions and multiple…

Chemical Physics · Physics 2024-07-23 Thomas Plé , Louis Lagardère , Jean-Philip Piquemal

We present BioNIC, a multi-layer feedforward neural network for emotion classification, inspired by detailed synaptic connectivity graphs from the MICrONs dataset. At a structural level, we incorporate architectural constraints derived from…

Neural and Evolutionary Computing · Computer Science 2026-01-30 Diya Prasanth , Matthew Tivnan

Bosonic codes represent a promising route toward quantum error correction in continuous-variable systems, with direct relevance to experimental platforms such as circuit QED and optomechanics. However, their preparation and stabilization…

Quantum Physics · Physics 2025-10-28 Zheping Wu , Lingzhen Guo , Haobin Shi , Wei-Wei Zhang

Integrating functional magnetic resonance imaging (fMRI) connectivity data with phenotypic textual descriptors (e.g., disease label, demographic data) holds significant potential to advance our understanding of neurological conditions.…

Machine Learning · Computer Science 2025-03-31 Yanting Yang , Xiaoxiao Li

Brain connectivity analysis based on magnetic resonance imaging is crucial for understanding neurological mechanisms. However, edge-based connectivity inference faces significant challenges, particularly the curse of dimensionality when…

Methodology · Statistics 2025-12-23 Zijing Li , Chenhao Zeng , Shufei Ge

Considering the spectral properties of images, we propose a new self-attention mechanism with highly reduced computational complexity, up to a linear rate. To better preserve edges while promoting similarity within objects, we propose…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Fengyu Zhang , Ashkan Panahi , Guangjun Gao

Reconstructing neuronal circuits at the level of synapses is a central problem in neuroscience and becoming a focus of the emerging field of connectomics. To date, electron microscopy (EM) is the most proven technique for identifying and…

Quantitative Methods · Quantitative Biology 2014-12-05 Stephen M. Plaza , Toufiq Parag , Gary B. Huang , Donald J. Olbris , Mathew A. Saunders , Patricia K. Rivlin

Brain-inspired computation and information processing alongside compatibility with neuromorphic hardware have made spiking neural networks (SNN) a promising method for solving learning tasks in machine learning (ML). Spiking neurons are…

Neural and Evolutionary Computing · Computer Science 2022-07-08 Hafez Ghaemi , Erfan Mirzaei , Mahbod Nouri , Saeed Reza Kheradpisheh

The dynamic characteristics of functional network connectivity have been widely acknowledged and studied. Both shared and unique information has been shown to be present in the connectomes. However, very little has been known about whether…

Neurons and Cognition · Quantitative Biology 2020-06-18 Biao Cai , Gemeng Zhang , Aiying Zhang , Li Xiao , Wenxing Hu , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Classification of whole-brain functional connectivity MRI data with convolutional neural networks (CNNs) has shown promise, but the complexity of these models impedes understanding of which aspects of brain activity contribute to…

Neurons and Cognition · Quantitative Biology 2020-05-28 Matthew Leming , John Suckling

Accurate classification of brain tumors from magnetic resonance imaging (MRI) plays a critical role in early diagnosis and effective treatment planning. In this study, we propose a deep learning framework based on Vision Transformers (ViT)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Faisal Ahmed

As a prevalent and dynamically regulated epigenetic modification, 5-formylcytidine (f5C) is crucial in various biological processes. However, traditional experimental methods for f5C detection are often laborious and time-consuming,…

Genomics · Quantitative Biology 2024-04-23 Guohao Wang , Ting Liu , Hongqiang Lyu , Ze Liu