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Related papers: Silicene as a new ultrafast DNA sequencing device

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We propose a DNA sequencing scheme based on silicene nanopores. Using first principles theory, we compute the electrical properties of such pores in the absence and presence of nucleobases. Within a two-terminal geometry, we analyze the…

Quantitative Methods · Quantitative Biology 2014-05-16 Hatef Sadeghi , S. Bailey , Colin J. Lambert

The outstanding properties of graphene have laid the foundation for exploring graphene-like two-dimensional systems, commonly referred to as 2D-Xenes. Amongst them, silicene is a front-runner owing to its compatibility with current silicon…

Mesoscale and Nanoscale Physics · Physics 2022-03-02 Swastik Sahoo , Abhinaba Sinha , Namitha Anna Koshi , Seung-Cheol Lee , Satadeep Bhattacharjee , Bhaskaran Muralidharan

The success of graphene for nanopore DNA sequencing has shown that it is possible to explore other potential single-atom and few-atom thick layers of elemental 2D materials beyond graphene (e.g., phosphorene and silicene). Using density…

Mesoscale and Nanoscale Physics · Physics 2021-12-15 Matthew B. Henry , Mukesh Tumbapo , Benjamin O. Tayo

This article reviews silicene, a relatively new allotrope of silicon, which can also be viewed as the silicon version of graphene. Graphene is a two-dimensional material with unique electronic properties qualitatively different from those…

Materials Science · Physics 2014-04-24 L. C. Lew Yan Voon , G. G. Guzmán-Verri

We present a tight-binding model study of a two-terminal graphene nanopore device for sequential determination of DNA bases. Using Green's function technique we investigate the changes in electronic transport properties of the device due to…

Mesoscale and Nanoscale Physics · Physics 2022-06-20 Sourav Kundu , S. N. Karmakar

The fabrication of nanopores in atomically-thin graphene has recently been achieved and translocation of DNA has been demonstrated. Taken together with an earlier proposal to use graphene nanogaps for the purpose of DNA sequencing, this…

Instrumentation and Detectors · Physics 2011-05-16 Jariyanee Prasongkit , Anton Grigoriev , Biswarup Pathak , Rajeev Ahuja , Ralph H. Scheicher

We propose a water-immersed nucleobase-functionalized suspended graphene nanoribbon as an intrinsically selective device for nucleotide detection. The proposed sensing method combines Watson-Crick selective base pairing with graphene's…

Mesoscale and Nanoscale Physics · Physics 2016-02-17 Eugene Paulechka , Tsjerk A. Wassenaar , Kenneth Kroenlein , Andrei Kazakov , Alex Smolyanitsky

Graphene nanogaps and nanopores show potential for the purpose of electrical DNA sequencing, in particular because single-base resolution appears to be readily achievable. Here, we evaluated from first principles the advantages of a nanogap…

Mesoscale and Nanoscale Physics · Physics 2013-07-29 Jariyanee Prasongkit , Anton Grigoriev , Biswarup Pathak , Rajeev Ahuja , Ralph H. Scheicher

Successful isolation of graphene from graphite opened a new era for material science and con- densed matter physics. Due to this remarkable achievement, there has been an immense interest to synthesize new two dimensional materials and to…

Mesoscale and Nanoscale Physics · Physics 2016-08-11 Mehmet Yagmurcukardes , Cihan Bacaksiz , Fadıl Iyikanat , Engin Torun , R. Tugrul Senger , Francois M. Peeters , Hasan Sahin

Translocation of DNA through a nanopore with embedded electrodes is at the centre of new rapid inexpensive sequencing methods which allow distinguishing the four nucleobases by their different electronic structure. However, the subnanometer…

Mesoscale and Nanoscale Physics · Physics 2012-06-20 Yuhui He , Makusu Tsutsui , Ralph H. Scheicher , Masateru Taniguchi , Tomoji Kawai

In this study, we examine the mechanism of nanopore-based DNA sequencing using a voltage bias across a graphene nanoribbon. Using density functional theory and a non-equilibrium Green's function approach, we determine the transmission…

Mesoscale and Nanoscale Physics · Physics 2018-09-11 Hannah L. McFarland , Towfiq Ahmed , Jian-Xin Zhu , Alexander V. Balatsky , Jason T. Haraldsen

We propose an aqueous functionalized molybdenum disulfide nanoribbon suspended over a solid electrode as the first capacitive displacement sensor aimed at determining the DNA sequence. The detectable sequencing events arise from the…

Mesoscale and Nanoscale Physics · Physics 2016-09-16 A. Smolyanitsky , B. I. Yakobson , T. A. Wassenaar , E. Paulechka , K. Kroenlein

We propose two-terminal devices for DNA sequencing which consist of a metallic graphene nanoribbon with zigzag edges (ZGNR) and a nanopore in its interior through which the DNA molecule is translocated. Using the nonequilibrium Green…

Mesoscale and Nanoscale Physics · Physics 2012-01-26 Kamal K. Saha , Marija Drndic , Branislav K. Nikolic

Using full potential density functional calculations within local density approximation (LDA), we report our investigation of the structural electronic properties of silicene (the graphene analogue of silicon), the strips of which has been…

Mesoscale and Nanoscale Physics · Physics 2012-01-06 Harihar Behera , Gautam Mukhopadhyay

A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We propose and theoretically show the feasibility of a protocol for sequencing based on the distributions of transverse electrical currents of…

Soft Condensed Matter · Physics 2015-06-25 Johan Lagerqvist , Michael Zwolak , Massimiliano Di Ventra

Silicene is a one-atom-thick 2D crystal of silicon with a hexagonal lattice structure that is related to that of graphene but with atomic bonds that are buckled rather than flat. This buckling confers advantages on silicene over graphene,…

Materials Science · Physics 2013-10-31 Wei-Feng Tsai , Cheng-Yi Huang , Tay-Rong Chang , Hsin Lin , Horng-Tay Jeng , A. Bansil

Nanopores -- nanosized holes that can transport ions and molecules -- are very promising devices for genomic screening, in particular DNA sequencing. Both solid-state and biological pores suffer from the drawback, however, that the channel…

The ability to detect and discriminate DNA bases by reading it directly using simple and cost-effective methods is an important problem whose solution can produce significant value for areas such as cancer and human genetic disorders.…

Mesoscale and Nanoscale Physics · Physics 2021-12-02 Mukesh Tumbapo , Matthew B. Henry , Sanjiv K. Jha , Benjamin O. Tayo

Recently solid state nanopores nanogaps have generated a lot of interest in ultrafast DNA sequencing. However, there are challenges to slow down the DNA translocation process to achieve a single nucleobase resolution. A series of…

Applied Physics · Physics 2020-04-24 Rameshwar L. Kumawat , Priyanka Garg , Gargee Bhattacharyya , Biswarup Pathak

We have micromachined a silicon-chip device that transports DNA with a Brownian ratchet that rectifies the Brownian motion of microscopic particles. Transport properties for a DNA 50mer agree with theoretical predictions, and the DNA…

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