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Classical disease models use a mass action term as the interaction between infected and susceptible people in separate patches. We derive the equations when this interaction is a migration of people between patches. The results model what…

Biological Physics · Physics 2009-11-11 Larry S. Liebovitch , Ira B. Schwartz

We revisit a classical continuum model for the diffusion of multiple species with size-exclusion constraint, which leads to a degenerate nonlinear cross-diffusion system. The purpose of this article is twofold: first, it aims at a…

Analysis of PDEs · Mathematics 2022-08-04 Katharina Hopf , Martin Burger

We study genetic networks that produce many species of non-coding RNA molecules that are present at a moderate density, as typically exists in the cell. The associations of the many species of these RNA are modeled physically, taking into…

Genomics · Quantitative Biology 2014-09-08 J. M. Deutsch

In this paper we study collective decision making on a multi-population, represented by a regular network of groups of individuals. Each group consists of a collection of players and every player can choose between two options. A group is…

Optimization and Control · Mathematics 2020-11-18 Wouter Baar , Dario Bauso

In this paper, we studied phase-space analysis of a certain mathematical model of tumor growth with an immune responses and chemotherapy therapy. Mathematical modelling of this process is viewed as a potentially powerful tool in the…

Dynamical Systems · Mathematics 2018-03-15 Veli Shakhmurov , Akif Maharramov , Bunyad Shahmurzada

We consider an infinite-dimension SIS model introduced by Delmas, Dronnier and Zitt, with a more general incidence rate, and study its equilibria. Unsurprisingly, there exists at least one endemic equilibrium if and only if the basic…

Analysis of PDEs · Mathematics 2026-02-04 Jean-François Delmas , Kacem Lefki , Pierre-André Zitt

Dengue remains a major global public health concern due to its high mortality and economic burden. Mathematical modeling is essential to understand its transmission mechanisms and for evaluating intervention strategies. In this paper, we…

Populations and Evolution · Quantitative Biology 2026-04-28 Sourav Banerjee , Thomas Götz , Satyananda Panda

We show how concepts from statistical physics, such as order parameter, thermodynamic limit, and quantum phase transition, translate into biological concepts in mutation-selection models for sequence evolution and can be used there. The…

Statistical Mechanics · Physics 2007-05-23 Joachim Hermisson , Oliver Redner , Holger Wagner , Ellen Baake

The simultaneous emergence of several abrupt disease outbreaks or the extinction of some serotypes of multi-strain diseases are fingerprints of the interaction between pathogens spreading within the same population. Here, we propose a…

Physics and Society · Physics 2019-12-25 David Soriano-Paños , Fakhteh Ghanbarnejad , Sandro Meloni , Jesús Gómez-Gardeñes

In this paper we consider a competition system in which two diseases spread by contact. We characterize the system behavior, establishing that only some configurations are possible. In particular we discover that coexistence of the two…

Dynamical Systems · Mathematics 2014-04-06 Roberto Cavoretto , Simona Collino , Bianca Giardino , Ezio Venturino

Biological evolution of a population is governed by the fitness landscape, which is a map from genotype to fitness. However, a fitness landscape depends on the organisms environment, and evolution in changing environments is still poorly…

Populations and Evolution · Quantitative Biology 2022-09-26 Suman G Das , Joachim Krug , Muhittin Mungan

We investigate how a population's natural and vaccine immunity affects the competitive balance between two strains of an infectious disease with different epidemiological characteristics. Specifically, we consider the case where one strain…

Dynamical Systems · Mathematics 2023-12-27 Matthew D. Johnston , Bruce Pell , Jared Pemberton , David A. Rubel

In an attempt to explain the uniqueness of the coding mechanism of living cells as contrasted with multi-species structure of ecosystems we examine two models of individuals with some replicative properties. In the first model the system…

Statistical Mechanics · Physics 2009-10-31 A. Lipowski

A stochastic reaction-diffusion model is studied on a networked support. In each patch of the network two species are assumed to interact following a non-normal reaction scheme. When the interaction unit is replicated on a directed linear…

Clonal interference, competition between multiple co-occurring beneficial mutations, has a major role in adaptation of asexual populations. We provide a simple individual based stochastic model of clonal interference taking into account a…

Probability · Mathematics 2015-05-19 Sylvain Billiard , Charline Smadi

We consider within-host virus models with more than one strain and allow mutation between the strains. If there is no mutation, a Lyapunov function establishes global stability of the steady state corresponding to the fittest strain. For…

Cell Behavior · Quantitative Biology 2007-08-01 Patrick De Leenheer , Sergei S. Pilyugin

We examine the properties of a recently proposed model for antigenic variation in malaria which incorporates multiple epitopes and both long-lasting and transient immune responses. We show that in the case of a vanishing decay rate for the…

Chaotic Dynamics · Physics 2012-09-21 K. B. Blyuss , S. Gupta

Multidimensional systems coupled via complex networks are widespread in nature and thus frequently invoked for a large plethora of interesting applications. From ecology to physics, individual entities in mutual interactions are grouped in…

Physics and Society · Physics 2018-11-21 Giulia Cencetti , Franco Bagnoli , Giorgio Battistelli , Luigi Chisci , Duccio Fanelli

Building upon kinetic theory approaches for multi-agent systems and generalising them to scenarios where the total mass of the system is not conserved, we develop a modelling framework for phenotype-structured populations that makes it…

Analysis of PDEs · Mathematics 2025-10-20 Emanuele Bernardi , Tommaso Lorenzi , Andrea Tosin

We study a mathematical model describing the growth process of a population structured by age and a phenotypical trait, subject to aging, competition between individuals and rare mutations. Our goals are to describe the asymptotic behaviour…

Analysis of PDEs · Mathematics 2020-04-17 Samuel Nordmann , Benoît Perthame , Cécile Taing