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The idea that complex systems have a hierarchical modular organization originates in the early 1960s and has recently attracted fresh support from quantitative studies of large scale, real-life networks. Here we investigate the hierarchical…

Data Analysis, Statistics and Probability · Physics 2010-04-20 D. Meunier , R. Lambiotte , A. Fornito , K. D. Ersche , E. T. Bullmore

Mild cognitive impairment(MCI) is a precursor of Alzheimer's disease(AD), and the detection of MCI is of great clinical significance. Analyzing the structural brain networks of patients is vital for the recognition of MCI. However, the…

Neurons and Cognition · Quantitative Biology 2022-08-19 Heng Kong , Shuqiang Wang

The brain continually reorganizes its functional network to adapt to post-stroke functional impairments. Previous studies using static modularity analysis have presented global-level behavior patterns of this network reorganization.…

Computation · Statistics 2024-03-25 Kaichao Wu , Beth Jelfs , Katrina Neville , Wenzhen He , Qiang Fang

We analyze functional magnetic resonance imaging (fMRI) data from the Human Connectome Project (HCP) to match brain activities during a range of cognitive tasks. Our findings demonstrate that even basic linear machine learning models can…

Neurons and Cognition · Quantitative Biology 2025-10-08 Valeriya Kirova , Dzerassa Kadieva , Daniil Vlasenko , Isak B. Blank , Fedor Ratnikov

In a recent paper, Bassett et al. (2011) have analyzed the static and dynamic organization of functional brain networks in humans. We here focus on the first claim made in this paper, which states that the static modular structure of such…

Quantitative Methods · Quantitative Biology 2011-06-30 Cedric E. Ginestet , Jonny O'Muircheartaigh , Owen G. O'Daly , Andrew Simmons

Many biological tissues feature a heterogeneous network of fibers whose tensile and bending rigidity contribute substantially to these tissues' elastic properties. Rigidity percolation has emerged as a important paradigm for relating these…

Modularity plays an important role in brain networks' architecture and influences its dynamics and the ability to integrate and segregate different modules of cerebral regions. Alterations in community structure are associated with several…

Neurons and Cognition · Quantitative Biology 2018-05-14 M. Cinelli , I. Echegoyen , M. Oliveira , S. Orellana , T. Gili

The brain's functional connectivity fluctuates over time instead of remaining steady in a stationary mode even during the resting state. This fluctuation establishes the dynamical functional connectivity that transitions in a non-random…

Neurons and Cognition · Quantitative Biology 2022-03-28 Shikuang Deng , Jingwei Li , B. T. Thomas Yeo , Shi Gu

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

Background: Non-linear alterations in brain network connectivity may represent early neural signatures of Alzheimer's disease (AD) pathology in cognitively normal older adults. Understanding these changes and their cognitive relevance may…

Neurons and Cognition · Quantitative Biology 2026-04-22 Junjie Wu , Benjamin B Risk , Taylor A James , Nicholas Seyfried , David W Loring , Felicia C Goldstein , Allan I Levey , James J Lah , Deqiang Qiu

Diffusion MRI (dMRI) streamline tractography, the gold standard for in vivo estimation of brain white matter (WM) pathways, has long been considered indicative of macroscopic relationships with WM microstructure. However, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Tian Yu , Yunhe Li , Michael E. Kim , Chenyu Gao , Qi Yang , Leon Y. Cai , Susane M. Resnick , Lori L. Beason-Held , Daniel C. Moyer , Kurt G. Schilling , Bennett A. Landman

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

The fast growth of social networks and their data access limitations in recent years has led to increasing difficulty in obtaining the complete topology of these networks. However, diffusion information over these networks is available, and…

Social and Information Networks · Computer Science 2025-10-01 Maryam Ramezani , Aryan Ahadinia , Erfan Farhadi , Hamid R. Rabiee

Criticality has been conjectured as an integral part of neuronal network dynamics. Operating at a critical threshold requires precise parameter tuning and a corresponding mechanism remains an open question. Recent studies have suggested…

Neurons and Cognition · Quantitative Biology 2021-04-19 Nikita Gutjahr , Philipp Hövel , Aline Viol

We study the large-scale topological and dynamical properties of real Internet maps at the autonomous system level, collected in a three years time interval. We find that the connectivity structure of the Internet presents average…

Statistical Mechanics · Physics 2009-11-07 Alexei Vazquez , Romualdo Pastor-Satorras , Alessandro Vespignani

We study functional activity in the human brain using functional Magnetic Resonance Imaging and recently developed tools from network science. The data arise from the performance of a simple behavioural motor learning task. Unsupervised…

Transition points mark qualitative changes in the macroscopic properties of large complex systems. Explosive transitions, exhibiting properties of both continuous and discontinuous phase transitions, have recently been uncovered in network…

Physics and Society · Physics 2021-06-01 Nora Molkenthin , Malte Schröder , Marc Timme

Although numerous studies report significant sex differences in functional connectivity, these differences do not sufficient to reveal specific functional disparities among brain regions or the topological differences in brain networks.…

Quantitative Methods · Quantitative Biology 2024-10-10 Wenyu Chen , Ling Zhan , Yunsong Luo , Jiang Qiu , Tao Jia

The structural human connectome (i.e.\ the network of fiber connections in the brain) can be analyzed at ever finer spatial resolution thanks to advances in neuroimaging. Here we analyze several large data sets for the human brain network…

Neurons and Cognition · Quantitative Biology 2016-06-08 Michael T. Gastner , Géza Ódor

Magnetic resonance diffusion tensor imaging (DTI) is a critical tool for neural disease diagnosis. However, long scan time greatly hinders the widespread clinical use of DTI. To accelerate image acquisition, a feature-enhanced joint…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Lang Zhang , Jinling He , Dong Liang , Hairong Zheng , Yanjie Zhu