Related papers: Geometry shapes evolution of early multicellularit…
To analyze the evolutionary emergence of structural complexity in physical processes we introduce a general, but tractable, model of objects that interact to produce new objects. Since the objects--\emph{$epsilon$-machines}--have well…
Soft surfaces, spanning vastly different environmental and biomedical settings, are frequently colonised by surface-associated bacteria. Yet, how soft surfaces govern bacterial dynamics and their self-organisation into colonies remains…
We study the emergence of cell differentiation under the assumption of the existence of a given number of tradeoffs between genes encoding different functions. In the model the viability of colonies is determined by the capability of their…
Much recent work has explored molecular and population-genetic constraints on the rate of protein sequence evolution. The best predictor of evolutionary rate is expression level, for reasons which have remained unexplained. Here, we…
One of the major characteristics of living organisms is metabolic rate, which is the amount of energy produced per unit of time. When the mass of organisms increases, the metabolic rate also increases (usually as a power function of mass),…
We have performed fully self-consistent $N$-body simulations of star clusters near the Galactic center (GC). Such simulations have not been performed because it is difficult to perform fast and accurate simulations of such systems using…
Competition between random genetic drift and natural selection plays a central role in evolution: Whereas non-beneficial mutations often prevail in small populations by chance, mutations that sweep through large populations typically confer…
Star clusters - open and globulars - experience dynamical evolution on time scales shorter than their age. Consequently, open and globular clusters provide us with unique dynamical laboratories for learning about two-body relaxation, mass…
Natural selection favors the more successful individuals. This is the elementary premise that pervades common models of evolution. Under extreme conditions, however, the process may no longer be probabilistic. Those that meet certain…
Lymphocyte populations, stimulated in vitro or in vivo, grow as cells divide. Stochastic models are appropriate because some cells undergo multiple rounds of division, some die, and others of the same type in the same conditions do not…
In this thesis, we aim to further elucidate the phenomenon of galaxy evolution in the environment of galaxy clusters using the methodology of numerical simulations. For that, we have developed hydrodynamic models in which idealized gas-rich…
Globular clusters (GCs) host multiple stellar populations differing in their chemical and dynamical properties. A number of models for the formation of multiple populations predict that the subsystem of second generation (SG) stars is…
In the present paper we propose an improvement of the Gillespie algorithm allowing us to study the time evolution of an ensemble of chemical reactions occurring in a varying volume, whose growth is directly related to the amount of some…
We present a model for cell growth, division and packing under soft constraints that arise from the deformability of the cells as well as of a membrane that encloses them. Our treatment falls within the framework of diffuse interface…
Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inheritance of a gradualistic view that has been challenged at…
Establishing a quantitative connection between the population growth rate and the generation times of single cells is a prerequisite for understanding evolutionary dynamics of microbes. However, existing theories fail to account for the…
We perform $N$-body simulations of star clusters in time-dependant galactic potentials. Since the Milky Way was built-up through mergers with dwarf galaxies, its globular cluster population is made up of clusters formed both during the…
Existing theories for the evolution of aging and death treat senescence as a side-effect of strong selection for fertility. These theories are well-developed mathematically, but fit poorly with emerging experimental data. The data suggest…
The aim of this paper is two-fold. First, we propose a new computational method to investigate the particularities of evolution. Second, we apply this method to a model of gene regulatory networks (GRNs) and explore the evolution of…
Globular clusters (GCs) constitute a system which is evolving because of various interactions with the galactic environment. Evolution may be the explanation of many observed features of Globular Cluster Systems (GCSs); the different radial…