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A theoretical model is presented for early evolutionary cell sorting within cellular aggregates. The model involves an energy-saving mechanism and principles of collective self-organization analogous to those observed in bicycle pelotons…

Populations and Evolution · Quantitative Biology 2019-02-21 Hugh Trenchard

Yeast cells grown in culture can spontaneously synchronize their respiration, metabolism, gene expression and cell division. Such metabolic oscillations in synchronized cultures reflect single-cell oscillations, but the relationship between…

Genomics · Quantitative Biology 2014-06-16 Nikolai Slavov , David Botstein , Amy Caudy

Most cells possess the capacity to locomote. Alone or collectively, this allows them to adapt, to rearrange, and to explore their surroundings. The biophysical characterization of such motile processes, in health and disease, has so far…

Biological Physics · Physics 2021-05-05 Vincent E. Debets , Liesbeth M. C. Janssen , Cornelis Storm

Scaling relations for globular clusters (GC) differ from scaling relations for pressure supported (elliptical) galaxies. We show that two-body relaxation is the dominant mechanism in shaping the bivariate dependence of density on mass and…

Astrophysics of Galaxies · Physics 2015-12-07 Mark Gieles , Poul Alexander

The path toward the emergence of life in our biosphere involved several key events allowing for the persistence, reproduction and evolution of molecular systems. All these processes took place in a given environmental context and required…

Disordered Systems and Neural Networks · Physics 2025-04-14 Ricard Solé , Manlio De Domenico

The transition from monolayers to multilayered structures in bacterial colonies is a fundamental step in biofilm development. Observed across different morphotypes and species, this transition is triggered within freely growing bacterial…

Soft Condensed Matter · Physics 2021-03-16 Zhihong You , Daniel J. G. Pearce , Anupam Sengupta , Luca Giomi

Cytasters have been underestimated in terms of their potential relevance to embryonic development and evolution. From the perspective discussed herein, structures such as the multiciliated cells of comb rows and balancers supporting…

Tissues and Organs · Quantitative Biology 2022-10-21 Jaime Cofre

We use direct N-body simulations to investigate the evolution of star clusters with large size-scales with the particular goal of understanding the so-called extended clusters observed in various Local Group galaxies, including M31 and…

Astrophysics of Galaxies · Physics 2015-05-19 Jarrod R. Hurley , A. Dougal Mackey

The primary goal in cluster analysis is to discover natural groupings of objects. The field of cluster analysis is crowded with diverse methods that make special assumptions about data and address different scientific aims. Despite its…

Genomics · Quantitative Biology 2018-06-07 Gary K. Chen , Eric Chi , John Ranola , Kenneth Lange

A central goal of evolutionary biology is to explain the origins and distribution of diversity across life. Beyond species or genetic diversity, we also observe diversity in the circuits (genetic or otherwise) underlying complex functional…

Populations and Evolution · Quantitative Biology 2018-06-06 Ali Tehrani-Saleh , Thomas LaBar , Christoph Adami

Biological systems reach hierarchical complexity that has no counterpart outside the realm of biology. Undoubtedly, biological entities obey the fundamental physical laws. Can today's physics provide an explanatory framework for…

Statistical Mechanics · Physics 2022-10-12 Yuri I. Wolf , Mikhail I. Katsnelson , Eugene V. Koonin

The discovery of multiple stellar populations in globular clusters has implications for all the aspects of the study of these stellar systems. In this paper, by means of N-body simulations, we study the evolution of binary stars in…

In this paper we present the first mathematical analysis of the protein interaction network found in the yeast, S. cerevisiae. We show that, (a) the identified protein network display a characteristic scale-free topology that demonstrate…

Statistical Mechanics · Physics 2009-11-07 Hawoong Jeong , Sean P. Mason , Albert-Laszlo Barabasi , Zoltan N. Oltvai

New information has recently become available on the fundamental plane for various samples of early-type galaxies with redshift up to 1.3, both in clusters and in the field. This information is reviewed and clues are derived on the…

Astrophysics · Physics 2007-05-23 Sperello di Serego Alighieri , Barbara Lanzoni

We analyze evolutionary dynamics in a confluent, branching cellular population, such as in a growing duct, vasculature, or in a branching microbial colony. We focus on the coarse-grained features of the evolution and build a statistical…

Populations and Evolution · Quantitative Biology 2022-02-15 Adam S. Bryant , Maxim O. Lavrentovich

Evolutionary experiments with microbes are a powerful tool to study mutations and natural selection. These experiments, however, are often limited to the well-mixed environments of a test tube or a chemostat. Since spatial organization can…

Populations and Evolution · Quantitative Biology 2012-05-02 Kirill S Korolev , Melanie J I Müller , Nilay Karahan , Andrew W Murray , Oskar Hallatschek , David R Nelson

Morphogenesis of complex body shapes is reproducible despite the noise inherent in the underlying morphogenetic processes. However, how these morphogenetic processes work together to achieve this reproducibility remains unclear. Here, we…

Cell Behavior · Quantitative Biology 2025-12-24 Dominic K Devlin , Austen RD Ganley , Nobuto Takeuchi

Evolution produces complex and structured networks of interacting components in chemical, biological, and social systems. We describe a simple mathematical model for the evolution of an idealized chemical system to study how a network of…

Adaptation and Self-Organizing Systems · Physics 2014-03-05 Sanjay Jain , Sandeep Krishna

The process of galaxy cluster formation likely leaves an imprint on the properties of its individual member galaxies. Understanding this process is essential for uncovering the evolutionary connections between galaxies and cosmic…

Evolutions of X-ray clusters of galaxies are studied by N-body (shell model) + mesh code (TVD) simulations on the assumption of spherical symmetry. We consider a density perturbation of $10^{15} M_{\odot}$ composed of dark matter and gas in…

Astrophysics · Physics 2009-10-30 Motokazu Takizawa , Shin Mineshige
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