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On-chip photodetectors are essential components in optical communications as they convert light into an electrical signal. Photobolometers are type of photodetector that functions through a resistance change caused by electronic temperature…

Optics · Physics 2023-09-27 Jacek Gosciniak

Machine learning models for medical images can help physicians diagnose and manage diseases. However, due to the fact that medical image annotation requires a great deal of manpower and expertise, as well as the fact that clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Can Li , Sheng Shao , Junyi Qu , Shuchao Pang , Mehmet A. Orgun

Single-molecule detection at a nanometric interface in a femtomolar solution, can take weeks as the encounter rate between the diffusing molecule to be detected and the transducing nano-device is negligibly small. On the other hand, several…

Designing terahertz sensors with high sensitivity to detect nanoscale thin films and single biomolecule presents a significant challenge, and addressing these obstacles is crucial for unlocking their full potential in scientific research…

More than twenty years ago, scientists succeeded in pushing the limits of optical detection to single molecules using fluorescence. This breakthrough has revolutionized biophysical measurements, but restrictions in photophysics and labeling…

Biological Physics · Physics 2015-06-17 Marek Piliarik , Vahid Sandoghdar

This study introduces a dual-band plasmonic absorber designed for simultaneous sensing applications in the near-infrared (NIR) and mid-infrared (MIR) regions. The absorber, composed of silver nanostructures on a metal plate with a…

Optics · Physics 2024-11-20 Ayon Sarker , Sajid Muhaimin Choudhury

The ability to perform noninvasive, non-contact measurements of electric signals produced by action potentials is essential in biomedicine. A key method to do this is to remotely sense signals by the magnetic field they induce. Existing…

Transition metal dichalcogenides have shown great promise in the field of gas sensing due to their high catalytic activity and unique electronic properties. They can effectively interact with various gas molecules, making them suitable…

Applied Physics · Physics 2024-09-11 Jemal Yimer Damte , Hassan Ataalite

The nitrogen vacancy (NV) center in diamond has emerged as a leading solid-state quantum sensor for applications including magnetometry, electrometry, thermometry, and chemical sensing. However, an outstanding challenge for practical…

Matrix Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) is a cornerstone in biomolecular analysis, offering precise identification of pathogens through unique mass spectral signatures. Yet, its reliance on labor-intensive…

Machine Learning · Computer Science 2025-11-24 Kyle M. Regan , Michael McLoughlin , Wayne A. Bryden , Gonzalo R. Arce

The NV center in a diamond is a quantum sensor with exceptional quality for highly sensitive nanoscale analysis of NMR spectra and thermometry. In this study, we investigate nanoscale phase change detection of lipid bilayers utilizing…

Miniaturized atomic magnetometers, particularly spin-exchange relaxation-free atomic magnetometers, have been emerging in clinical imaging applications such magnetocardiography and magnetoencephalography. Miniaturization, portability, and…

Atomic Physics · Physics 2022-04-28 Xiaojie Li , Zhihao Guo , Rui Yang , Yanying Feng

Electronic excitations and ionisations produced by electron impact are key processes in the radiation-induced damage mechanisms in materials of biological relevance, underlying important medical and technological applications, including…

Chemical Physics · Physics 2021-08-04 Pablo de Vera , Isabel Abril , Rafael Garcia-Molina

THz technologies are a powerful tool for label-free detection of biomolecules. However, significant reduction of the lower detection limit is required to apply THz-sensors in biomedical diagnosis. This paper reports an ultrasensitive…

Magnetic nanostructures sustaining different kinds of optical modes have been used for magnetometry and label-free ultrasensitive refractive index probing, where the main challenge is the realization of compact devices able to transfer this…

Nanodiamonds containing nitrogen-vacancy (NV) centers are promising quantum sensors for biological applications thanks to their sub-micron spatial resolution, biocompatibility, and versatile multi-modal responses. However, the optically…

Applied Physics · Physics 2026-03-23 Shuo Wang , Ming-Zhong Ai , Jing-Wei Fan , Junchen Ye , Chao Lin , Quan Li , Ren-Bao Liu

We describe two different modes for electronically detecting an adsorbed molecule using a nanoscale transistor. The attachment of an ionic molecular target shifts the threshold voltage through modulation of the depletion layer…

Mesoscale and Nanoscale Physics · Physics 2008-08-19 S. Vasudevan , K. Walczak , N. Kapur , M. Neurock , A. W. Ghosh

Microfluidic channels with embedded ion permselective medium under the application of electric current are commonly used for electrokinetic processes as on-chip ion concentration polarization (ICP) and bioparticle preconcentration to…

Fluid Dynamics · Physics 2022-11-22 Barak Sabbagh , Sinwook Park , Gilad Yossifon

A device model of biological molecule sensors based on semiconductor nanowires has been developed. This model of a bioFET is based on the concept of the electrolytic absolute electrode potential. From that starting point a semiconductor…

Chemical Physics · Physics 2012-12-14 M. W. Denhoff

A high-performance wide-angle refractive index sensor based on a simple onedimensional (1D) metallic deep nanogroove array with high aspect ratio is experimentally fabricated and demonstrated. The 1D deep groove array is featured by the…