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This paper proposes a novel wireless, battery-free, and label-free biosensor for minimally invasive and non-invasive permittivity sensing for applications such as detecting glucose levels in the interstitial dermal fluid. The miniaturized,…

Applied Physics · Physics 2022-10-19 Rehab S. Hassan

CMOS-based sensor array chips provide new and attractive features as compared to today's standard tools for medical, diagnostic, and biotechnical applications. Examples for molecule- and cell-based approaches and related circuit design…

Rapid progress in plasmonics biosensors and immunosensors brings many methodologies to employ resonant subwavelength structures associated with the physics of multipoles, Fano resonances, and analogous moments. Here, we review a broad range…

Applied Physics · Physics 2018-09-18 Arash Ahmadivand , Burak Gerislioglu

Biosensing based on whispering-gallery mode (WGM) resonators has been continuously studied with great attention due to its excellent sensitivity guaranteeing the label-free detection. However, its practical impact is insignificant to date…

Applied Physics · Physics 2020-01-08 Yeseul Kim , Hansuek Lee

The aim of this paper is to introduce current advances in technology that could enable the development of fully drinkable and autonomous bio-electronic CMOS sensors in the form of dust particles, capable of identifying the source of a…

Applied Physics · Physics 2018-05-17 Sandro Carrara , Pantelis Georgiou

We propose a new label-free ultrasonic sensor, which comprises a slot wave-guide and double silicon-on-insulator (SOI) slot micro-ring resonators. The all-optical sensors do not suffer from electromagnetic interference. We choose to…

Optics · Physics 2022-04-04 Cheng Mei Zhang , Chao Ying Zhao

Bacterial infectious diseases are a major threat to human health. Timely and sensitive pathogenic bacteria detection is crucial in identifying the bacterial contaminations and preventing the spread of infectious diseases. Due to limitations…

Silicon nanochannel biological field effect transistors have been developed for glucose detection. The device is nanofabricated from a silicon-on-insulator wafer with a top-down approach and surface functionalized with glucose oxidase. The…

Biological Physics · Physics 2008-02-14 Xihua Wang , Yu Chen , Katherine A. Gibney , Shyamsunder Erramilli , Pritiraj Mohanty

We report progress toward a CMOS-integrated quantum diamond biosensing platform that combines nitrogen-vacancy (NV) centers in diamond with a custom 40 nm CMOS Single-Photon Avalanche Diode (SPAD) array. The system integrates on-chip active…

A low-cost chipless RFID sensor tag to determine the dielectric properties of materials is presented. The sensor is based on a depolarizing dipole resonator loaded with printed capacitors whose capacitance depends on the permittivity of the…

A surface plasmon resonance imaging biosensor based on $\text{MoS}_2$ deposited on Aluminium substrate is designed for high imaging sensitivity and detection accuracy. The proposed biosensor exhibits better performance than graphene-based…

Mesoscale and Nanoscale Physics · Physics 2018-12-19 Yi Xu , Lin Wu , Lay Kee Ang

Decentralized diagnostic testing that is accurate, portable, quantitative, and capable of making multiple simultaneous measurements of different biomarkers at the point-of-need remains an important unmet need in the post-pandemic world.…

Label-free biosensors, including conventional quartz-crystal-microbalance (QCM) biosensor, are seriously affected by nonspecific adsorption of contaminants involved in analyte solution, and it is exceptionally difficult to extract the…

Biological Physics · Physics 2021-12-15 Kentaro Noi , Arihiro Iwata , Fumihito Kato , Hirotsugu Ogi

Silicon-based photonic biosensors, such as microring resonators and Mach-Zehnder interferometers, offer significant potential for the detection of analytes at low concentrations. To enhance response time and improve the limit of detection…

Optics · Physics 2024-07-01 Anders Henriksson , Peter Neubauer , Mario Birkholz

Micro-scale implantable medical devices (IMDs) extend the immense benefits of sensors used in health management. However, their development is limited by many requirements and challenges, such as the use of safe materials, size…

Information Theory · Computer Science 2018-06-19 Michael Okwori , Ali Behfarnia , Phanikumar Vuka , Ali Eslami

Single-chip CMOS-based biosensors that feature microcantilevers as transducer elements are presented. The cantilevers are functionalized for the capturing of specific analytes, e.g., proteins or DNA. The binding of the analyte changes the…

Hardware Architecture · Computer Science 2011-11-09 K. -U. Kirstein , Y. Li , M. Zimmermann , C. Vancura , T. Volden , W. H. Song , J. Lichtenberg , A. Hierlemannn

Our growing ability to tailor healthcare to the needs of individuals has the potential to transform clinical treatment. However, the measurement of multiple biomarkers to inform clinical decisions requires rapid, effective, and affordable…

With ever increasing research on magnetic nano systems it is shown to have great potential in the areas of magnetic storage, biosensing, magnetoresistive insulation etc. In the field of biosensing specifically Spin Valve sensors coupled…

Emerging Technologies · Computer Science 2015-12-01 Tathagata Srimani , Bibhas Manna , Anand Kumar Mukhopadhyay , Kaushik Roy , Mrigank Sharad

The achievement of all-fibre functional nano-modules for subcellular label-free measurement has long been pursued due to the limitations of manufacturing techniques. In this paper, a compact all-fibre label-free nano-sensor composed of a…

Molecular dipoles near interfaces emit highly directional radiation due to near-field interactions, making surface-bound fluorophores sensitive probes of local physicochemical changes. We introduce smart coverslips, stably coated with…