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A statistical thermodynamic development is given of a new implicit solvent model that avoids the traditional system size limitations of computer simulation of macromolecular solutions with periodic boundary conditions. This implicit solvent…

Chemical Physics · Physics 2009-10-31 Lawrence R. Pratt , Susan B. Rempe

A parameterization strategy for molecular models on the basis of force fields is proposed, which allows a rapid development of models for small molecules by using results from quantum mechanical (QM) ab initio calculations and thermodynamic…

Chemical Physics · Physics 2009-04-22 Bernhard Eckl , Jadran Vrabec , Hans Hasse

Realistic modeling of ionic systems necessitates taking explicitly account of many-body effects. In molecular dynamics simulations, it is possible to introduce explicitly these effects through the use of additional degrees of freedom. Here…

A numerical method is presented for first-principle simulations of charged colloidal dispersions in electrolyte solutions. Utilizing a smoothed profile for colloid-solvent boundaries, efficient mesoscopic simulations are enabled for…

Soft Condensed Matter · Physics 2007-05-23 Kang Kim , Ryoichi Yamamoto

We present the theory and implementation of a Poisson-Boltzmann implicit solvation model for electrolyte solutions. This model can be combined with arbitrary electronic structure methods that provide an accurate charge density of the…

Computational Physics · Physics 2020-01-08 Christopher J. Stein , John M. Herbert , Martin Head-Gordon

The Polarizable Continuum Model (PCM) can be used in conjunction with Density Functional Theory (DFT) and its time-dependent extension (TDDFT) to simulate the electronic and optical properties of molecules and nanoparticles immersed in a…

Materials Science · Physics 2015-10-28 Alain Delgado , Stefano Corni , Stefano Pittalis , Carlo Andrea Rozzi

Continuum solvation models enable electronic structure calculations of systems in liquid environments, but because of the large number of empirical parameters, they are limited to the class of systems in their fit set (typically organic…

We use a new configuration-based version of linear response theory to efficiently solve self-consistent mean field equations relating an effective single particle potential to the induced density. The versatility and accuracy of the method…

Statistical Mechanics · Physics 2015-05-20 Zhonghan Hu , John D. Weeks

Quantum chemical calculations on quantum computers have been focused mostly on simulating molecules in gas-phase. Molecules in liquid solution are however most relevant for Chemistry. Continuum solvation models represent a good compromise…

Quantum Physics · Physics 2022-11-14 Davide Castaldo , Soran Jahangiri , Alain Delgado , Stefano Corni

Inferring properties of macroscopic solutions from molecular simulations is complicated by the limited size of systems that can be feasibly examined with a computer. When long-ranged electrostatic interactions are involved, the resulting…

Statistical Mechanics · Physics 2018-08-14 Stephen J. Cox , Phillip L. Geissler

The development of numerical methods capable of simulating realistic materials with strongly correlated electrons, with controllable errors, is a central challenge in quantum many-body physics. Here we describe how a hybrid between…

Strongly Correlated Electrons · Physics 2015-04-23 Alexei A. Kananenka , Emanuel Gull , Dominika Zgid

A numerical method using implicit surface representations is proposed to solve the linearized Poisson-Boltzmann equations that arise in mathematical models for the electrostatics of molecules in solvent. The proposed method used an implicit…

Numerical Analysis · Mathematics 2018-04-04 Yimin Zhong , Kui Ren , Richard Tsai

Employing a classical density-functional description of liquid environments, we introduce a rigorous method for the diffusion quantum Monte Carlo calculation of free energies and thermodynamic averages of solvated systems that requires…

Density matrix embedding theory (Phys. Rev. Lett. 109, 186404 (2012)) and density embedding theory ((Phys. Rev. B 89, 035140 (2014)) have recently been introduced for model lattice Hamiltonians and molecular systems. In the present work,…

Chemical Physics · Physics 2016-11-25 Ireneusz W. Bulik , Weibing Chen , Gustavo E. Scuseria

Within the framework of continuum mechanics, the full description Of joint motion of elastic bodies and compressible viscous fluids with taking into account thermal effects is given by the system consisting of the mass, momentum, and energy…

Analysis of PDEs · Mathematics 2007-05-23 Anvarbek M. Meirmanov , Sergei A. Sazhenkov

Continuum solvation methods can provide an accurate and inexpensive embedding of quantum simulations in liquid or complex dielectric environments. Notwithstanding a long history and manifold applications to isolated systems in open boundary…

Materials Science · Physics 2014-12-02 Oliviero Andreussi , Nicola Marzari

The increasing number of experimental observations on highly concentrated electrolytes and ionic liquids show qualitative features that are distinct from dilute or moderately concentrated electrolytes, such as self-assembly, multiple-time…

Chemical Physics · Physics 2018-02-08 Nir Gavish , Doron Elad , Arik Yochelis

The response of polar solvents to ions and polar molecules dictates many fundamental molecular processes. To understand such electrostatically-driven solvation processes, one ideally would probe the dielectric response of a solvent to an…

Chemical Physics · Physics 2025-08-12 Renjie Zhao , Richard C. Remsing , John D. Weeks

Integral equation theory of molecular liquids based on statistical mechanics is quite promising as an essential part of multiscale methodology for chemical and biomolecular nanosystems in solution. Beginning with a molecular interaction…

Soft Condensed Matter · Physics 2015-10-23 A. Kovalenko

An integral equation-based numerical method for scattering from multi-dielectric cylinders is presented. Electromagnetic fields are represented via layer potentials in terms of surface densities with physical interpretations. The existence…

Computational Physics · Physics 2019-05-01 Johan Helsing , Anders Karlsson