English

An implicit boundary integral method for computing electric potential of macromolecules in solvent

Numerical Analysis 2018-04-04 v4 Biological Physics Computational Physics Biomolecules

Abstract

A numerical method using implicit surface representations is proposed to solve the linearized Poisson-Boltzmann equations that arise in mathematical models for the electrostatics of molecules in solvent. The proposed method used an implicit boundary integral formulation to derived a linear system defined on Cartesian nodes in a narrowband surrounding the closed surface that separate the molecule and the solvent. The needed implicit surfaces is constructed from the given atomic description of the molecules, by a sequence of standard level set algorithms. A fast multipole method is applied to accelerate the solution of the linear system. A few numerical studies involving some standard test cases are presented and compared to other existing results.

Keywords

Cite

@article{arxiv.1709.08070,
  title  = {An implicit boundary integral method for computing electric potential of macromolecules in solvent},
  author = {Yimin Zhong and Kui Ren and Richard Tsai},
  journal= {arXiv preprint arXiv:1709.08070},
  year   = {2018}
}

Comments

28 pages

R2 v1 2026-06-22T21:52:42.965Z