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We propose a protein model based on a hierarchy of constraints that force the protein to follow certain pathways when changing conformation. The model exhibits a first order phase transition, cooperativity and is exactly solvable. It also…

Condensed Matter · Physics 2015-06-25 Alex Hansen , Mogens H. Jensen , Kim Sneppen , Giovanni Zocchi

Complex colloidal cluster morphologies are desirable for the fabrication of advanced materials, such as photonic crystals and meta-materials, and can be formed through evaporation-driven packing. By coupling lattice Boltzmann and discrete…

Soft Condensed Matter · Physics 2026-05-07 Junyu Yang , Abhinav Naga , Xitong Zhang , Halim Kusumaatmaja

The world of two-dimensional crystals is of great significance for the design and study of structural and functional materials with novel properties. The world of two-dimensional crystals is of great significance for the design and study of…

Materials Science · Physics 2015-06-16 Simiso Mkhonta , Ken Elder , Zhi-Feng Huang

The achievement of selectivity in the formation of cubic diamond is challenging due to the emergence of competing phases such as its hexagonal polymorph or clathrates possessing similar free energy. Although both polymorphs exhibit a…

Soft Condensed Matter · Physics 2025-01-14 Dariusz Tarasewicz , Edyta Raczyłło , Wojciech Rżysko , Łukasz Baran

A major issue in biology is the understanding of the interactions between proteins. These interactions can be described by a network, where the proteins are modeled by nodes and the interactions by edges. The origin of these protein…

Biological Physics · Physics 2011-08-01 Christian M. Schneider , Lucilla de Arcangelis , Hans J. Herrmann

The formation of quasi-spherical cages from protein building blocks is a remarkable self-assembly process in many natural systems, where a small number of elementary building blocks are assembled to build a highly symmetric icosahedral…

All liquids (except helium due to quantum effects) crystallize at low temperatures, forming ordered structures. The competition between disorder, which stabilizes the liquid phase, and energy, which favors the ordered crystalline structure,…

Soft Condensed Matter · Physics 2013-07-09 Frank Smallenburg , Francesco Sciortino

Many essential cellular processes, including cell division and the establishment of cell polarity during embryogenesis, are regulated by pattern-forming proteins. These proteins often need to bind to a substrate, such as the cell membrane,…

Soft Condensed Matter · Physics 2025-10-08 Amélie Chardac , Michael M. Norton , Jonathan Touboul , Guillaume Duclos

Despite numerous efforts from numerical approaches to complement experimental measurements, several fundamental challenges have still hindered one's ability to truly provide an atomistic picture of the nucleation process in nanocrystals.…

Real dusty crystals are inhomogeneous due to the presence of external forces. We suggest approximations for calculations of different types of inhomogeneous DC (chain and DC with a few slabs) in the equilibrium state. The results are in a…

Plasma Physics · Physics 2009-10-31 L. I. Podloubny , P. P. J. M. Schram , S. A. Trigger

Protein aggregation in cell membrane is vital for the majority of biological functions. Recent experimental results suggest that transmembrane domains of proteins such as $\alpha$-helices and $\beta$-sheets have different structural…

Biological Physics · Physics 2016-01-20 Hamidreza Jafarinia , Atefeh Khoshnood , Mir Abbas Jalali

Biomolecular self-assembly spatially segregates proteins with a limited number of binding sites (valence) into condensates that coexist with a dilute phase. We develop a many-body lattice model for a three-component system of proteins with…

Soft Condensed Matter · Physics 2022-01-13 Saroj Kumar Nandi , Daniel Österle , Meta Heidenreich , Emmanuel D. Levy , Samuel A. Safran

We investigate experimentally and numerically the defect configurations emerging when a cholesteric liquid crystal is confined to a spherical shell. We uncover a rich scenario of defect configurations, some of them non-existent in nematic…

Soft Condensed Matter · Physics 2017-09-13 Alexandre Darmon , Michael Benzaquen , Simon Čopar , Olivier Dauchot , Teresa Lopez-Leon

Micrometre sized colloidal particles can be viewed as large atoms with tailorable size, shape and interactions. These building blocks can assemble into extremely rich structures and phases, in which the thermal motions of particles can be…

Soft Condensed Matter · Physics 2017-11-10 Bo Li , Di Zhou , Yilong Han

We perform extensive monomer-resolved computer simulations of suitably-designed amphiphilic dendritic macromolecules over a broad range of densities, proving the existence and stability of cluster crystals formed in these systems, as…

Soft Condensed Matter · Physics 2013-05-06 Dominic A. Lenz , Ronald Blaak , Christos N. Likos , Bianca M. Mladek

Contact processes (CP's) with particle creation requiring a minimal neighborhood (restrictive or threshold CP's) present a novel sort of discontinuous absorbing transitions, that revealed itself robust under the inclusion of different…

Statistical Mechanics · Physics 2016-03-30 Salete Pianegonda , C. E. Fiore

Crystallization and vitrification of tetrahedral liquids are important both from a fundamental and a technological point of view. Here, we study via extensive umbrella sampling Monte Carlo computer simulations the nucleation barriers for a…

Soft Condensed Matter · Physics 2015-05-28 Ivan Saika-Voivod , Flavio Romano , Francesco Sciortino

We investigate the structural and thermodynamic properties of a model of particles with $2$ patches of type $A$ and $10$ patches of type $B$. Particles are placed on the sites of a face centered cubic lattice with the patches oriented along…

Soft Condensed Matter · Physics 2015-06-18 J. M. Tavares , N. G. Almarza , M. M. Telo da Gama

We use specialized Monte Carlo simulation methods and moment free energy calculations to provide conclusive evidence that dense polydisperse spheres at equilibrium demix into coexisting fcc phases, with more phases appearing as the spread…

Statistical Mechanics · Physics 2013-05-29 Peter Sollich , Nigel B. Wilding

Inside a cell, heterotypic proteins assemble in inhomogeneous, crowded systems where the abundance of these proteins vary with cell types. While some protein complexes form putative structures that can be visualized with imaging, there are…

Biomolecules · Quantitative Biology 2021-09-15 Andrei G. Gasic , Atrayee Sarkar , Margaret S. Cheung