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A detailed treatment of an electro-optical trap for polar molecules, realized by embedding an optical trap within a uniform electrostatic field, is presented and the trap's properties analyzed and discussed. The electro-optical trap offers…

Atomic Physics · Physics 2022-06-15 Bretislav Friedrich

Optical interfaces for quantum emitters are a prerequisite for implementing quantum networks. Here, we couple single molecules to the guided modes of an optical nanofiber. The molecules are embedded within a crystal that provides…

Optical molecular sensing techniques are often limited by the refractive index change associated with the probed interactions. In this work, we present a closed form analytical model to estimate the magnitude of optical refractive index…

Applied Physics · Physics 2017-12-04 Harish Sasikumar , Manoj M. Varma

In living organisms, proteins and peptides are often under the influence of mechanical forces, especially in confined spaces such as membrane channels, ribosome exit tunnel, or proteasome gate. Due to the directional nature of proteins as…

Biological Physics · Physics 2025-02-25 Felipe C. Nepomuceno , Michal H. Kolář

Within a closed system, physical interactions are reciprocal. However, the effective interaction between two entities of an open system may not obey reciprocity. Here, we describe a non-reciprocal interaction between nanoparticles which is…

Optics · Physics 2024-02-02 Amir M. Jazayeri , Sohila Abdelhafiz , Aristide Dogariu

The manipulation of nanoscale matter has the potential to revolutionize a variety of fields across nanoscience and technology. Here, we demonstrate experimentally and characterize numerically a device that combines the benefits of…

Mesoscale and Nanoscale Physics · Physics 2024-08-13 Marco Riccardi , Olivier J. F. Martin

Optical tweezers have revolutionized particle manipulation at the micro- and nanoscale, playing a critical role in fields such as plasmonics, biophysics, and nanotechnology. While traditional optical trapping methods primarily rely on…

Optics · Physics 2025-03-31 Ashutosh Shukla , Rahul Chand , Sneha Boby , G. V. Pavan Kumar

The optical trapping of polymeric nanofibers and the characterization of the rotational dynamics are reported. A strategy to apply a torque to a polymer nanofiber, by tilting the trapped fibers using a symmetrical linear polarized Gaussian…

Complex DNA topological structures, including polymer loops, are frequently observed in biological processes when protein molecules simultaneously bind to several distant sites on DNA. However, the molecular mechanisms of formation of these…

Soft Condensed Matter · Physics 2019-11-12 Jaeoh Shin , Anatoly B. Kolomeisky

Optomechanics, which explores the fundamental coupling between light and mechanical motion, has made important advances in both exploring and manipulating macroscopic mechanical oscillators down to the quantum level. However, dynamical…

The internal dynamics of macro-molecular systems is characterized by widely separated time scales, ranging from fraction of ps to ns. In ordinary molecular dynamics simulations, the elementary time step dt used to integrate the equation of…

Soft Condensed Matter · Physics 2015-05-19 Pietro Faccioli

Accurate quantification of protein-nanoparticle interactions is essential for applications in nanobiotechnology, nanomedicine, and drug delivery. Motivated by recent computational and experimental work, we combine coarse-grained united-atom…

Investigations of molecular bonds between single molecules and molecular complexes by the dynamic force spectroscopy are subject to large fluctuations at nanoscale and possible other aspecific binding, which mask the experimental output.…

Molecular Networks · Quantitative Biology 2015-05-14 Jelena Zivković , Marija Mitrović , Luuk Janssen , Hans A. Heus , Bosiljka Tadić , Sylvia Speller

Collisions between cold molecules are essential for studying fundamental aspects of quantum chemistry, and may enable formation of quantum degenerate molecular matter by evaporative cooling. However, collisions between trapped, naturally…

Optical trapping, also known as optical tweezing or optical levitation, is a technique that uses highly focused laser beams to manipulate micro- and nanoscopic particles. In optical traps driven by high-energy pulses, material non-linearity…

Metal nanoantennas enable the manipulation of light emission and detection at the single photon level by confining light into very small volumes. Emitters coupled to these plasmonic structures are thus ideal candidates for usage in quantum…

Optics · Physics 2020-08-11 Nathan Kimmitt , Esther A. Wertz

Time-division multiplexing presents an attractive opportunity to probe multi-colloidal interactions in optical traps at short time-scales. In this paper, we demonstrate a stroboscopic system capable of arbitrary control of multiple trapped…

Instrumentation and Detectors · Physics 2020-05-27 Thomas Dixon , Peter Reece

Fast detection and characterization of single nanoparticles such as viruses, airborne aerosols and colloidal particles are considered to be particularly important for medical applications, material science and atmospheric physics. In…

We study the effect of a coupling between two motor domains in highly-processive motor protein complexes. A simple stochastic discrete model, in which the two parts of the protein molecule interact through some energy potential, is…

Soft Condensed Matter · Physics 2009-11-11 Evgeny B. Stukalin , Hubert Phillips , Anatoly B. Kolomeisky

Understanding protein dynamics are essential for deciphering protein functional mechanisms and developing molecular therapies. However, the complex high-dimensional dynamics and interatomic interactions of biological processes pose…

Quantitative Methods · Quantitative Biology 2025-05-15 Tiexin Qin , Mengxu Zhu , Chunyang Li , Terry Lyons , Hong Yan , Haoliang Li
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