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Large genomic and imaging datasets can be used to train models that learn meaningful representations of cellular systems. Across domains, model performance improves predictably with dataset size and compute budget, providing a basis for…

Quantitative Methods · Quantitative Biology 2026-02-23 Gokul Gowri , Igor Sadalski , Dan Raviv , Peng Yin , Jonathan Rosenfeld , Allon M. Klein

The occurrence of stochastic resonance in bistable systems undergoing anomalous diffusions, which arise from density-dependent fluctuations, is investigated with emphasis on the analytical formulation of the problem as well as a possible…

Statistical Mechanics · Physics 2021-03-16 F. Naha Nzoupe , Alain M. Dikande

Noise can induce coherent oscillations in excitable systems without periodic orbits. Here, we establish a method to derive a hybrid system approximating the noise-induced coherent oscillations in excitable systems and further perform phase…

Adaptation and Self-Organizing Systems · Physics 2022-05-26 Jinjie Zhu , Yuzuru Kato , Hiroya Nakao

The intrinsic stochasticity of gene expression can lead to large variability of protein levels across a population of cells. Variability (or noise) in protein distributions can be modulated by cellular mechanisms of gene regulation; in…

Molecular Networks · Quantitative Biology 2011-03-02 Tao Jia , Rahul V. Kulkarni

We consider the influence of stochastic perturbations on stability of a unique positive equilibrium of a difference equation subject to prediction-based control. These perturbations may be multiplicative $$x_{n+1}=f(x_n)-\left( \alpha +…

Dynamical Systems · Mathematics 2016-06-08 Elena Braverman , Conall Kelly , Alexandra Rodkina

In this work, we consider a multi-population system where the dynamics of each agent evolve according to a system of stochastic differential equations in a general functional setup, determined by the global state of the system. Each agent…

Probability · Mathematics 2025-07-24 Giuseppe D'Onofrio , Anderson Melchor Hernandez

Stochastic dynamics of several systems can be modeled via piecewise deterministic time evolution of the state, interspersed by random discrete events. Within this general class of systems, we consider time-triggered stochastic hybrid…

Systems and Control · Computer Science 2018-04-27 Mohammad Soltani , Abhyudai Singh

When modelling time series, it is common to decompose observed variation into a "signal" process, the process of interest, and "noise", representing nuisance factors that obfuscate the signal. To separate signal from noise, assumptions must…

Methodology · Statistics 2020-11-11 Richard Creswell , Ben Lambert , Chon Lok Lei , Martin Robinson , David Gavaghan

We consider the influence of correlated noise on the stability of synchronisation of oscillators on a general network using the Kuramoto model for coupled phases $\theta_i$. Near the fixed point $\theta_i \approx \theta_j \ \forall i,j$ the…

Statistical Mechanics · Physics 2013-04-29 Mathew Zuparic , Alexander C. Kalloniatis

The large-scale integration of intermittent renewable energy has brought serious challenges to the frequency security of power systems. In this paper, a novel nonparametric stochastic analysis method of system dynamic frequency is proposed…

Systems and Control · Electrical Eng. & Systems 2023-12-19 Can Wan , Yupeng Ren , Ping Ju

Diverse complex dynamical systems are known to exhibit abrupt regime shifts at bifurcation points of the saddle-node type. The dynamics of most of these systems, however, have a stochastic component resulting in noise driven regime shifts…

Statistical Mechanics · Physics 2013-10-29 Sayantari Ghosh , Amit Kumar Pal , Indrani Bose

In numerous systems in biophysics and related fields, scientists measure (with very smart methods) individual molecules (e.g. biopolymers (proteins, DNA, RNA, etc), nano - crystals, ion channels), aiming at finding a model from the data.…

Subcellular Processes · Quantitative Biology 2013-06-12 Ophir Flomenbom

Patterns in complex systems store hidden information of the system which is needed to be explored. We present a simple model of cytokine and T-cells interaction and studied the model within stochastic framework by constructing Master…

Populations and Evolution · Quantitative Biology 2022-09-23 Moirangthem Shubhakanta Singh , Mairembam Kelvin Singh , R. K. Brojen Singh

Stochastic resonance is a phenomenon in which noise enhances the response of a system to an input signal. The brain is an example of a system that has to detect and transmit signals in a noisy environment, suggesting that it is a good…

Neurons and Cognition · Quantitative Biology 2017-10-16 Bertha Vázquez-Rodríguez , Andrea Avena-Koenigsberger , Olaf Sporns , Alessandra Griffa , Patric Hagmann , Hernán Larralde

We consider driven many-particle models which have a phase transition between an active and an absorbing phase. Like previously studied models, we have particle conservation, but here we introduce an additional symmetry - when two particles…

Statistical Mechanics · Physics 2017-01-18 Daniel Hexner , Dov Levine

Fluctuations and noise may alter the behavior of dynamical systems considerably. For example, oscillations may be sustained by demographic fluctuations in biological systems where a stable fixed point is found in the absence of noise. We…

Adaptation and Self-Organizing Systems · Physics 2009-11-13 Richard P. Boland , Tobias Galla , Alan J. McKane

Quantum systems are inherently susceptible to noise -- a notorious factor that induces decoherence and limits the performance of quantum applications. To mitigate its detrimental effects, various techniques have been developed, including…

Quantum Physics · Physics 2025-05-21 Yu-Bo Hou , Xiaoan Ai , Ruizhe You , Changchun Zhong

We consider the general problem of describing the dynamics of subnetworks of larger biochemical reaction networks, e.g. protein interaction networks involving complex formation and dissociation reactions. We propose the use of model…

Quantitative Methods · Quantitative Biology 2020-08-26 Barbara Bravi , Katy J. Rubin , Peter Sollich

Quantum stochastic processes are widely used in describing open quantum systems and in the context of quantum foundations. Physically relevant quantum stochastic processes driven by multiplicative colored noise are generically non-Markovian…

Quantum Physics · Physics 2026-03-12 Aritro Mukherjee

We develop a system for measurements of power spectra of transmitted light intensity fluctuations, in which the extraneous noise, including shot noise, is reduced. In essence, we just apply light, measure the power of the transmitted light…

Atomic Physics · Physics 2023-07-19 Takahisa Mitsui , Kenichiro Aoki
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