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Objective: The most relevant source of signal contamination in the cardiac electrophysiology (EP) laboratory is the ubiquitous powerline interference (PLI). To reduce this perturbation, algorithms including common fixed bandwidth and…
Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk…
The aorta is the body's largest arterial vessel, serving as the primary pathway for oxygenated blood within the systemic circulation. Aortic aneurysms consistently rank among the top twenty causes of mortality in the United States. Thoracic…
Wearable devices enable theoretically continuous, longitudinal monitoring of physiological measurements like step count, energy expenditure, and heart rate. Although the classification of abnormal cardiac rhythms such as atrial fibrillation…
Sustained spiral waves, also known as rotors, are pivotal mechanisms in persistent atrial fibrillation (AF). Stochasticity is inevitable in nonlinear biological systems such as the heart; however, it is unclear how noise affects the…
Cardiovascular diseases (CVDs) are the number one cause of death worldwide. While there is growing evidence that the atrial fibrillation (AF) has strong associations with various CVDs, this heart arrhythmia is usually diagnosed using…
Cardiovascular diseases stand as the primary global cause of mortality. Among the various imaging techniques available for visualising the heart and evaluating its function, echocardiograms emerge as the preferred choice due to their safety…
Atrial fibrillation (AF) is a prevalent cardiac arrhythmia associated with elevated health risks, where timely detection is pivotal for mitigating stroke-related morbidity. This study introduces an innovative hybrid methodology integrating…
Taking the cue from experiments on actin growth on spherical beads, we formulate and solve a model problem describing the accretion of an incompressible elastic solid on a rigid sphere due to attachment of diffusing free particles. One of…
Strokes are still one of the leading causes for death after heart diseases and cancer in all over the world. Most strokes happen because an artery that carries blood uphill from the heart to the head gets clogged. Most of the time, as with…
Cardiovascular diseases and their associated disorder of heart failure are one of the major death causes globally, being a priority for doctors to detect and predict its onset and medical consequences. Artificial Intelligence (AI) allows…
Morphological variations in the left atrial appendage (LAA) are associated with different levels of ischemic stroke risk for patients with atrial fibrillation (AF). Studying LAA morphology can elucidate mechanisms behind this association…
Ventricular arrhythmias comprise a group of disorders which manifest clinically in a variety of ways from ventricular premature beats (VPB) and no sustained ventricular tachycardia (in healthy subjects) to sudden cardiac death due to…
Computer simulations of blood flow in patients with anomalous aortic origin of a coronary artery (AAOCA) have the promise to provide insight into this complex disease. They provide an in-silico experimental platform to explore possible…
Aortic root dilation and propensity to dissection are typical manifestations of the Marfan Syndrome (MS), a genetic defect leading to the degeneration of the elastic fibres. Dilation affects the structure of the flow and, in turn, altered…
Radiofrequency catheter ablation (RFCA) is an effective treatment for cardiac arrhythmias. Although generally safe, it is not completely exempt from the risk of complications. The great flexibility of computational models can be a major…
Disruptions in the normal rhythmic functioning of the heart, termed as arrhythmia, often result from qualitative changes in the excitation dynamics of the organ. The transitions between different types of arrhythmia are accompanied by…
Cardiovascular Diseases (CVDs) are the leading cause of death worldwide, taking 17.9 million lives annually. Abdominal Aortic Calcification (AAC) is an established marker for CVD, which can be observed in lateral view Vertebral Fracture…
A stroke occurs when an artery in the brain ruptures and bleeds or when the blood supply to the brain is cut off. Blood and oxygen cannot reach the brain's tissues due to the rupture or obstruction resulting in tissue death. The Middle…
Cardiac models are examples of excitable systems and can support stable spiral waves. For certain parameter values, however, these spiral waves can become unstable, resulting in spiral defect chaos (SDC), characterized by the continuous…