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Myocardial infarction (MI) is the leading cause of mortality in the world that occurs due to a blockage of the coronary arteries feeding the myocardium. An early diagnosis of MI and its localization can mitigate the extent of myocardial…
In this work we propose a new method for the rhythm classification of short single-lead ECG records, using a set of high-level and clinically meaningful features provided by the abductive interpretation of the records. These features…
Arrhythmias are potentially fatal disruptions to the normal heart rhythm, but their underlying dynamics is still poorly understood. Theoretical modeling is an important tool to fill this gap. Typical studies often employ detailed…
In the time-series analysis, the time series motifs and the order patterns in time series can reveal general temporal patterns and dynamic features. Triadic Motif Field (TMF) is a simple and effective time-series image encoding method based…
Radiofrequency (RF) catheter ablation has transformed treatment for tachyarrhythmias and has become first-line therapy for some tachycardias. The precise localization of the arrhythmogenic site and the positioning of the RF catheter over…
Cardiac fibrillation is characterized by chaotic and disintegrated spiral wave dynamics patterns, whereas sinus rhythm shows synchronized excitation patterns. To determine functional correlations among cardiomyocytes during complex…
Electrocardiogram (ECG) is one of the non-invasive and low-risk methods to monitor the condition of the human heart. Any abnormal pattern(s) in the ECG signal is an indicative measure of malfunctioning of the heart, termed as arrhythmia.…
Knowledge of the mechanical properties of the aorta is essential as important concerns regarding the treatment of aortic pathologies, such as atherosclerosis, aneurysms and dissections, are fundamentally mechanobiological. A comprehensive…
This chapter reviews the different methodological aspects of the ab ini-tio modeling of dislocations. Such simulations are now frequently used to study the dislocation core, i.e. the region in the immediate vicinity of the line defect where…
Cardiac arrhythmia is a prevalent and significant cause of morbidity and mortality among cardiac ailments. Early diagnosis is crucial in providing intervention for patients suffering from cardiac arrhythmia. Traditionally, diagnosis is…
Obstructive sleep apnea (OSA) is believed to contribute significantly to atrial fibrillation (AF) development in certain patients. Recent studies indicate a rising risk of AF with increasing OSA severity. However, the commonly used…
The disruption of circadian rhythm is a cardinal symptom for Alzheimer's disease (AD) patients. The full circadian rhythm orchestration of gene expression in the human brain and its inherent associations with AD remain largely unknown. We…
Cardiovascular diseases are a pervasive global health concern, contributing significantly to morbidity and mortality rates worldwide. Among these conditions, arrhythmia, characterized by irregular heart rhythms, presents formidable…
Infarction- or ischaemia-induced cardiac fibrosis can be arrythmogenic. We use mathematcal models for diffuse fibrosis ($\mathcal{DF}$), interstitial fibrosis ($\mathcal{IF}$), patchy fibrosis ($\mathcal{PF}$), and compact fibrosis…
This paper deals with the mathematical analysis and numerical simulation of a new nonlinear ablation system modeling radiofrequency ablation phenomena in cardiac tissue, {which incorporates the effects of blood flow on the heat generated…
We derive an equation that governs the spatiotemporal dynamics of small amplitude alternans in paced cardiac tissue. We show that a pattern-forming linear instability leads to the spontaneous formation of stationary or traveling waves whose…
Introduction: The presence of fibrillatory waves (f-waves) is important in the diagnosis of atrial fibrillation (AF), which has motivated the development of methods for f-wave extraction. We propose a novel approach to benchmarking methods…
Cardiac diseases are among the leading causes of morbidity and mortality worldwide, which requires accurate and timely diagnostic strategies. In this study, we introduce an innovative approach that combines deep learning image registration…
During cardiac arrhythmias, dynamical patterns of electrical activation form and evolve, which are of interest to understand and cure heart rhythm disorders. The analysis of these patterns is commonly performed by calculating the local…
The study of pathological cardiac conditions such as arrhythmias, a major cause of mortality in heart failure, is becoming increasingly informed by computational simulation, numerically modelling the governing equations. This can provide…