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In recent years, the growing availability of biomedical datasets featuring numerous longitudinal covariates has motivated the development of several multi-step methods for the dynamic prediction of survival outcomes. These methods employ…

Methodology · Statistics 2026-01-14 Mirko Signorelli , Sophie Retif

Alignment algorithms usually rely on simplified models of gaps for computational efficiency. Based on an isomorphism between alignments and physical helix-coil models, we show in statistical mechanics that alignments with realistic laws for…

Genomics · Quantitative Biology 2015-06-26 E. Yeramian , E. Debonneuil

Stochastic models, based on random processes, may lead to power law distributions, which provide long range correlations. The observation of power law behavior and the presence of long range correlations in biological systems has been…

Statistical Mechanics · Physics 2008-03-26 Thomas Oikonomou

We consider a trait-structured population subject to mutation, birth and competition of logistic type, where the number of coexisting types may fluctuate. Applying a limit of rare mutations to this population while keeping the population…

Probability · Mathematics 2011-12-05 Nicolas Champagnat , Amaury Lambert

The dynamical evolution of many economic, sociological, biological and physical systems tends to be dominated by a relatively small number of unexpected, large changes (`extreme events'). We study the large, internal changes produced in a…

Disordered Systems and Neural Networks · Physics 2009-11-07 D. Lamper , S. Howison , N. F. Johnson

Causal analyses of longitudinal data generally assume that the qualitative causal structure relating variables remains invariant over time. In structured systems that transition between qualitatively different states in discrete time steps,…

Methodology · Statistics 2020-11-11 Ranjani Srinivasan , Jaron Lee , Rohit Bhattacharya , Narges Ahmidi , Ilya Shpitser

All living languages change over time. The causes for this are many, one being the emergence and borrowing of new linguistic elements. Competition between the new elements and older ones with a similar semantic or grammatical function may…

Computation and Language · Computer Science 2020-06-17 Andres Karjus , Richard A. Blythe , Simon Kirby , Kenny Smith

Concerns with the safety and reliability of applying large-language models (LLMs) in unpredictable real-world applications motivate this study, which examines how task phrasing can lead to presumptions in LLMs, making it difficult for them…

Computation and Language · Computer Science 2026-05-04 Kenneth J. K. Ong

It is notoriously difficult to predict the behaviour of a complex self-organizing system, where the interactions among dynamical units form a heterogeneous topology. Even if the dynamics of each microscopic unit is known, a real…

Information Theory · Computer Science 2013-10-01 Rick Quax , Andrea Apolloni , Peter M. A. Sloot

Density dependence is important in the ecology and evolution of microbial and cancer cells. Typically, we can only measure net growth rates, but the underlying density-dependent mechanisms that give rise to the observed dynamics can…

Populations and Evolution · Quantitative Biology 2025-06-04 Linh Huynh , Jacob G. Scott , Peter J. Thomas

Real-world optimisation problems are often dynamic. Previously good solutions must be updated or replaced due to changes in objectives and constraints. It is often claimed that evolutionary algorithms are particularly suitable for dynamic…

Neural and Evolutionary Computing · Computer Science 2016-07-13 Duc-Cuong Dang , Thomas Jansen , Per Kristian Lehre

Many real-world systems exhibit ``noisy'' evolution in time; interpreting their finitely-sampled behavior as arising from continuous-time processes (in the It\^o or Stratonovich sense) has led to significant success in modeling and analysis…

Mathematical Physics · Physics 2025-07-29 David Sabin-Miller , Daniel M. Abrams

Most population models assume that individuals within a given population are identical, that is, the fundamental role of variation is ignored. Here we develop a general approach to modeling heterogeneous populations with discrete…

Populations and Evolution · Quantitative Biology 2007-05-23 Georgy P. Karev , Artem S. Novozhilov , Faina S. Berezovskaya

Biological and social systems are structured at multiple scales, and the incentives of individuals who interact in a group may diverge from the collective incentive of the group as a whole. Mechanisms to resolve this tension are responsible…

Populations and Evolution · Quantitative Biology 2023-05-31 Daniel B. Cooney , Simon A. Levin , Yoichiro Mori , Joshua B. Plotkin

Density dependent Markov population processes with countably many types can often be well approximated over finite time intervals by the solution of the differential equations that describe their average drift, provided that the total…

Probability · Mathematics 2014-06-05 A. D. Barbour , Malwina Luczak

We study the effects of discrete, randomly distributed time delays on the dynamics of a coupled system of self-propelling particles. Bifurcation analysis on a mean field approximation of the system reveals that the system possesses patterns…

Pattern Formation and Solitons · Physics 2015-06-05 Luis Mier-y-Teran-Romero , Brandon Lindley , Ira B. Schwartz

Verhulst logistic curve either grows OR decays, depending on the {\it growth rate} parameter value. A similar situation is found in the Gompertz law about human mortality. However, growth can neither be infinite nor reach a finite steady…

Biological Physics · Physics 2015-03-19 Marcel Ausloos

In a standard bifurcation of a dynamical system, the stationary points (or more generally attractors) change qualitatively when varying a control parameter. Here we describe a novel unusual effect, when the change of a parameter, e.g. a…

Populations and Evolution · Quantitative Biology 2017-04-26 V. I. Yukalov , E. P. Yukalova , D. Sornette

We study contact epidemic models for the spread of infective diseases in finite populations. The size dependence enters in the infection rate. The dynamics of such models is then analyzed within the deterministic approximation, as well as…

Populations and Evolution · Quantitative Biology 2020-04-07 Ph. Blanchard , S. Nicolis

Scientists often use observational time series data to study complex natural processes, but regression analyses often assume simplistic dynamics. Recent advances in deep learning have yielded startling improvements to the performance of…

Machine Learning · Computer Science 2023-04-21 Cory Shain , William Schuler
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