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This paper deals with the three-dimensional narrow escape problem in dendritic spine shaped domain, which is composed of a relatively big head and a thin neck. The narrow escape problem is to compute the mean first passage time of Brownian…

Mathematical Physics · Physics 2017-02-24 Hyundae Lee , Xiaofei Li , Yuliang Wang

This paper considers the two-dimensional narrow escape problem in a domain which is composed of a relatively big head and several thin necks. The narrow escape problem is to compute the mean first passage time(MFPT) of a Brownian particle…

Mathematical Physics · Physics 2023-12-05 Xiaofei Li , Shengqi Lin

The narrow escape problem consists of deriving the asymptotic expansion of the solution of a drift-diffusion equation with the Dirichlet boundary condition on a small absorbing part of the boundary and the Neumann boundary condition on the…

Analysis of PDEs · Mathematics 2010-03-12 Habib Ammari , Kostis Kalimeris , Hyeonbae Kang , Hyundae Lee

We present an efficient method to solve the narrow capture and narrow escape problems for the sphere. The narrow capture problem models the equilibrium behavior of a Brownian particle in the exterior of a sphere whose surface is reflective,…

Numerical Analysis · Mathematics 2021-08-03 Jason Kaye , Leslie Greengard

Questions of flux regulation in biological cells raise renewed interest in the narrow escape problem. The often inadequate expansions of the narrow escape time are due to a not so well known fact that the boundary singularity of Green's…

Mathematical Physics · Physics 2009-11-13 A. Singer , Z. Schuss , D. Holcman

We expose here a novel application of the so-called coupled complex boundary method -- first put forward by Cheng et al. (2014) to deal with inverse source problems -- in the framework of shape optimization for solving the exterior…

Optimization and Control · Mathematics 2022-11-16 Julius Fergy T. Rabago

We present a meshless Schwarz-type non-overlapping domain decomposition method based on artificial neural networks for solving forward and inverse problems involving partial differential equations (PDEs). To ensure the consistency of…

Machine Learning · Computer Science 2023-07-25 Shamsulhaq Basir , Inanc Senocak

Reaction-Diffusion systems arise in diverse areas of science and engineering. Due to the peculiar characteristics of such equations, analytic solutions are usually not available and numerical methods are the main tools for approximating the…

Numerical Analysis · Mathematics 2024-09-16 Eddel Elí Ojeda Avilés , Jae-Hun Jung , Daniel Olmos Liceaga

A solution is developed for a convection-diffusion equation describing chemical transport with sorption, decay, and production. The problem is formulated in a finite domain where the appropriate conservation law yields Robin conditions at…

Analysis of PDEs · Mathematics 2007-05-23 W. J. Golz , J. R. Dorroh

We consider the kinetics of the imperfect narrow escape problem, i.e. the time it takes for a particle diffusing in a confined medium of generic shape to reach and to be adsorbed by a small, imperfectly reactive patch embedded in the…

Statistical Mechanics · Physics 2023-05-11 T. Guérin , M. Dolgushev , O. Bénichou , R. Voituriez

The recent approach based on Hamiltonian systems and the implicit parametri\-za\-tion theorem, provides a general fixed domain approximation method in shape optimization problems, using optimal control theory. In previous works, we have…

Optimization and Control · Mathematics 2022-05-03 Cornel Marius Murea , Dan Tiba

Cellular networks are often composed of thin tubules connecting much larger node compartments. These structures serve for active or diffusion transport of proteins. Examples are glial networks in the brain, the endoplasmic reticulum in…

Soft Condensed Matter · Physics 2024-07-31 Frédéric Paquin-Lefebvre , Kanishka Basnayake , David Holcman

This paper studies the $d$-dimensional extension of a fictitious domain penalization technique that we previously proposed for Neumann or Robin boundary conditions. We apply Droniou's approach for non-coercive linear elliptic problems to…

Analysis of PDEs · Mathematics 2024-07-18 Bouchra Bensiali , Jacques Liandrat

This work investigates a nonlocal sinh-Gordon equation with a singularly perturbed parameter in a ball. Under the Robin boundary condition, the solution asymptotically forms a quite steep boundary layer in a thin annular region, and rapidly…

Analysis of PDEs · Mathematics 2020-09-16 Chiun-Chang Lee

This work focuses on the development and analysis of a partitioned numerical method for moving domain, fluid-structure interaction problems. We model the fluid using incompressible Navier-Stokes equations, and the structure using linear…

Numerical Analysis · Mathematics 2020-07-03 Anyastassia Seboldt , Martina Bukač

Diffuse domain methods (DDMs) have garnered significant attention for approximating solutions to partial differential equations on complex geometries. These methods implicitly represent the geometry by replacing the sharp boundary interface…

Analysis of PDEs · Mathematics 2025-04-25 Toai Luong , Tadele Mengesha , Steven M. Wise , Ming Hei Wong

We study the narrow escape problem in the disk, which consists in identifying the first exit time and first exit point distribution of a Brownian particle from the ball in dimension 2, with reflecting boundary conditions except on small…

Analysis of PDEs · Mathematics 2024-04-09 Tony Lelièvre , Mohamad Rachid , Gabriel Stoltz

The narrow escape problem is a first-passage problem concerned with randomly moving particles in a physical domain, being trapped by absorbing surface traps (windows), such that the measure of traps is small compared to the domain size. The…

Mathematical Physics · Physics 2021-09-15 Vaibhava Srivastava , Alexei Cheviakov

A non-conventional shape optimization approach is introduced to address the identification of an obstacle immersed in a fluid described by the Stokes equation within a larger bounded domain, relying on boundary measurements on the…

Optimization and Control · Mathematics 2024-03-19 Julius Fergy Tiongson Rabago , Lekbir Afraites , Hirofumi Notsu

We study the asymptotic behaviour of the principal eigenvalue of a Robin (or generalised Neumann) problem with a large parameter in the boundary condition for the Laplacian in a piecewise smooth domain. We show that the leading asymptotic…

Spectral Theory · Mathematics 2007-05-23 Michael Levitin , Leonid Parnovski
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