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The quality of healthcare provided by hospitals is subject to considerable variability. Consequently, accurate measurements of hospital performance are essential for various decision-makers, including patients, hospital managers and health…

Applications · Statistics 2020-11-16 Eva van Weenen , Stefan Feuerriegel

Clinical prognostic models help inform decision-making by estimating a patient's risk of experiencing an outcome in the future. The net benefit is increasingly being used to assess the clinical utility of models. By calculating an…

Current clinical decision support systems (CDSSs) typically base their predictions on correlation, not causation. In recent years, causal machine learning (ML) has emerged as a promising way to improve decision-making with CDSSs by offering…

Human-Computer Interaction · Computer Science 2026-04-17 Domenique Zipperling , Lukas Schmidt , Benedikt Hahn , Niklas Kühl , Steven Kimbrough

Home-based care (HBC) delivers medical and care services in patients' living environments, offering unique opportunities for patient-centered care. However, patient agency is often inadequately represented in shared HBC planning processes.…

Human-Computer Interaction · Computer Science 2026-02-02 Sung-In Kim , Joonyoung Park , Bogoan Kim , Hwajung Hong

Medicine is moving from a curative discipline to a preventative discipline relying on personalised and precise treatment plans. The complex and multi level pathophysiological patterns of most diseases require a systemic medicine approach…

Computational Engineering, Finance, and Science · Computer Science 2020-07-21 Pietro Barbiero , Pietro Lió

Risk prediction is central to both clinical medicine and public health. While many machine learning models have been developed to predict mortality, they are rarely applied in the clinical literature, where classification tasks typically…

Machine Learning · Statistics 2017-12-05 Maggie Makar , Marzyeh Ghassemi , David Cutler , Ziad Obermeyer

Dynamic prediction of causal effects under different treatment regimes conditional on an individual's characteristics and longitudinal history is an essential problem in precision medicine. This is challenging in practice because outcomes…

Methodology · Statistics 2023-03-07 Yizhen Xu , Jisoo Kim , Laura K. Hummers , Ami A. Shah , Scott Zeger

Pathology foundation models (PFMs) achieve strong performance on diverse histopathology tasks, but their sensitivity to hospital-specific domain shifts remains underexplored. We systematically evaluate state-of-the-art PFMs on TCGA…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Mengliang Zhang

Healthcare systems generate diverse multimodal data, including Electronic Health Records (EHR), clinical notes, and medical images. Effectively leveraging this data for clinical prediction is challenging, particularly as real-world samples…

Machine Learning · Computer Science 2025-09-01 Xiaoyang Wang , Christopher C. Yang

Identifying relationships between molecular variations and their clinical presentations has been challenged by the heterogeneous causes of a disease. It is imperative to unveil the relationship between the high dimensional molecular…

Methodology · Statistics 2021-09-02 Wennan Chang , Changlin Wan , Yong Zang , Chi Zhang , Sha Cao

Large Language Models (LLMs) are increasingly demonstrating the potential to reach human-level performance in generating clinical summaries from patient-clinician conversations. However, these summaries often focus on patients' biology…

Predictive models are increasingly used to make various consequential decisions in high-stakes domains such as healthcare, finance, and policy. It becomes critical to ensure that these models make accurate predictions, are robust to shifts…

Machine Learning · Computer Science 2022-09-22 Murtuza N Shergadwala , Himabindu Lakkaraju , Krishnaram Kenthapadi

It is often the case that risk assessment and prognostics are viewed as related but separate tasks. This chapter describes a risk-based approach to prognostics that seeks to provide a tighter coupling between risk assessment and fault…

Systems and Control · Electrical Eng. & Systems 2025-08-18 John W. Sheppard

Hospital choice models often employ random utility theory and include waiting time as a choice determinant. When applied to evaluate health system improvement interventions, these models disregard that hospital choice in turn is a…

Optimization and Control · Mathematics 2023-06-29 Joris van de Klundert , Roberto Cominetti , Yun Liu , Qingxia Kong

Nowadays, hospitals are ubiquitous and integral to modern society. Patients flow in and out of a veritable whirlwind of paperwork, consultations, and potential inpatient admissions, through an abstracted system that is not without flaws.…

Artificial Intelligence · Computer Science 2016-09-21 Hugh Chen , Yusuf Erol , Eric Shen , Stuart Russell

Multiple chronic conditions (MCC) are one of the biggest challenges of modern times. The evolution of MCC follows a complex stochastic process that is influenced by a variety of risk factors, ranging from pre-existing conditions to…

Joint models have proven to be an effective approach for uncovering potentially hidden connections between various types of outcomes, mainly continuous, time-to-event, and binary. Typically, longitudinal continuous outcomes are…

Referral workflow inefficiencies, including misaligned referrals and delays, contribute to suboptimal patient outcomes and higher healthcare costs. In this study, we investigated the possibility of predicting procedural needs based on…

Cancer treatment outcomes are influenced not only by clinical and demographic factors but also by the collaboration of healthcare teams. However, prior work has largely overlooked the potential role of human collaboration in shaping patient…

Social and Information Networks · Computer Science 2025-12-04 Hsiao-Ying Lu , Kwan-Liu Ma

Background: Bayesian Networks (BNs) are probabilistic graphical models that leverage Bayes' theorem to portray dependencies and cause-and-effect relationships between variables. These networks have gained prominence in the field of health…

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