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Total-body positron emission tomography (PET) imaging has the potential to transform medical care of a number of diseases and augment our knowledge of systems biology. Various detector designs and geometries are currently under development…

This study focuses on developing a self-triggered data acquisition system and a noise reduction algorithm for the Multi-gap Resistive Plate Chamber (MRPC) Time-of-Flight Positron Emission Tomography (TOF-PET) system. The system integrates a…

Instrumentation and Detectors · Physics 2025-05-13 Jianing Liu , Yuelei Ma , Ziyang Chen , Zhenyan Li , Yi Wang , Baohong Guo , Dong Han , Yuanjing Li

J-PET is a photon detector built of plastic scintillators, which already has been commissioned for CPT studies in the decays of positronium. In the first experiment, J-PET has achieved a sensitivity to CPT violation at a level of 10^{-4},…

High Energy Physics - Phenomenology · Physics 2023-02-28 Neha Chug , Aleksander Gajos

Positron Emission Tomography using 2-[18F]-2deoxy-D-glucose as radiotracer (FDG-PET) is currently one of the most frequently applied functional imaging methods in clinical applications. The interpretation of FDG-PET data requires…

Tissues and Organs · Quantitative Biology 2020-01-22 Michele Piana , Giacomo Caviglia , Sara Sommariva

Pixelated PET systems produce higher count rates as they integrate several detecting channels per detector module. An increased data flow from the detectors posses higher needs on the bandwidth requirements. We aim to optimize the bandwidth…

Instrumentation and Detectors · Physics 2018-04-05 C. Zorraquino , L. Ferramacho , R. Bugalho , M. Zvolsky , T. Niknejad , J. C. Silva , S. Tavernier , P. Guerra , J. Varela , A. Santos

Reconstruction of the image in Positron Emission Tomographs (PET) requires the knowledge of the system response kernel which describes the contribution of each pixel (voxel) to each tube of response (TOR). This is especially important in…

The photoneutron source (PNS, phase 1), an electron linear accelerator (linac)-based pulsed neutron facility that uses the time-of-flight (TOF) technique, was constructed for the acquisition of nuclear data from the thorium molten salt…

PET is a functional imaging method that visualizes metabolic processes. TOF information can be derived from coincident detector signals and incorporated into image reconstruction to enhance the SNR. PET detectors are typically assessed by…

Instrumentation and Detectors · Physics 2025-04-24 Stephan Naunheim , Luis Lopes de Paiva , Vanessa Nadig , Yannick Kuhl , Stefan Gundacker , Florian Mueller , Volkmar Schulz

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

Intraoperative Gamma Probe (IPG) remains the current gold standard modality for sentinel lymph node identification and tumor removal in cancer patients. However, even alongside the optical dyes they do not meet with <5% false negative rates…

Medical Physics · Physics 2022-01-26 S. Sajedi , L. Blackberg , S. Majewski , H. Sabet

The synergistic interpretation of anatomical information from computed tomography (CT) and metabolic information from positron emission tomography (PET) is important to oncologic imaging. However, existing deep learning methods for PET/CT…

Image and Video Processing · Electrical Eng. & Systems 2026-05-22 Xiaofeng Liu , Qianru Zhang , Thibault Marin , Menghua Xia , Chi Liu , Georges El Fakhri , Jinsong Ouyang

This work is the second part of a simulation study investigating the processing of densely packed and moving granular assemblies by positron emission particle tracking (PEPT). Since medical PET scanners commonly used for PEPT are very…

This is a thought piece on data-intensive science requirements for databases and science centers. It argues that peta-scale datasets will be housed by science centers that provide substantial storage and processing for scientists who access…

Databases · Computer Science 2007-05-23 Jim Gray , David T. Liu , Maria Nieto-Santisteban , Alexander S. Szalay , David DeWitt , Gerd Heber

Parameter-efficient tuning (PET) aims to transfer pre-trained foundation models to downstream tasks by learning a small number of parameters. Compared to traditional fine-tuning, which updates the entire model, PET significantly reduces…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Kwonyoung Kim , Jungin Park , Jin Kim , Hyeongjun Kwon , Kwanghoon Sohn

In this study we address the feasibility and main properties of a positron emission tomograph (PET) based on RPCs. The concept, making use of the converter-plate principle, takes advantage of the intrinsic layered structure of RPCs and its…

Instrumentation and Detectors · Physics 2009-11-07 A. Blanco , V. Chepel , R. Ferreira-Marques , P. Fonte , M. I. Lopes , V. Peskov , A. Policarpo

Neutron capture cross-section measurements are fundamental in the study of astrophysical phenomena, such as the slow neutron capture (s-) process of nucleosynthesis operating in red-giant and massive stars. However, neutron capture…

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