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Positron Emission Tomography (PET) is a powerful medical imaging technique, but the design and evaluation of new PET scanner technologies present significant challenges. The process is typically divided into three major stages: 1. detector…

Instrumentation and Detectors · Physics 2026-01-30 J. Renner , J. J. Gómez-Cadenas , R. Soleti

This paper describes the data acquisition and trigger system of the Thin Time-of-flight PET (TT-PET) scanner. The system is designed to read out in the order of 1000 pixel sensors used in the scanner and to provide a reference timing signal…

Instrumentation and Detectors · Physics 2018-12-11 Y. Bandi , Y. Favre , D. Ferrere , D. Forshaw , R. Hanni , D. Hayakawa , G. Iacobucci , P. Lutz , A. Miucci , L. Paolozzi , E. Ripiccini , C. Tognina , P. Valerio , M. Weber

In this paper, we review physics- and data-driven reconstruction techniques for simultaneous positron emission tomography (PET) / magnetic resonance imaging (MRI) systems, which have significant advantages for clinical imaging of cancer,…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Abhejit Rajagopal , Andrew P. Leynes , Nicholas Dwork , Jessica E. Scholey , Thomas A. Hope , Peder E. Z. Larson

The TT-PET collaboration is developing a small animal TOF-PET scanner based on monolithic silicon pixel sensors in SiGe BiCMOS technology. The demonstrator chip, a small-scale version of the final detector ASIC, consists of a 3 x 10 pixel…

Historically, patient datasets have been used to develop and validate various reconstruction algorithms for PET/MRI and PET/CT. To enable such algorithm development, without the need for acquiring hundreds of patient exams, in this paper we…

Research conducted in the framework of the J-PET project aims to develop a cost-effective total-body positron emission tomography scanner. As a first step on the way to construct a full-scale J-PET tomograph from long strips of plastic…

We present simulations of whole-body low-dose time-of-flight positron emission tomography (TOF-PET) based on the direct surface production [1] by 511 keV gamma rays of energetic electrons via the Photo-electric and Compton Effects,…

Time-of-flight (TOF) information provides more accurate location data for annihilation photons, thereby enhancing the quality of PET reconstruction images and reducing noise. List-mode reconstruction has a significant advantage in handling…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Rui Hu , Chenxu Li , Kun Tian , Jianan Cui , Yunmei Chen , Huafeng Liu

Time-Over-Threshold (TOT) technique is being used widely due to its implications in developing the multi channel readouts mainly when fast signal processing is required. Using TOT technique as a measure of energy loss instead of charge…

In positron emission tomography (PET), time-of-flight (TOF) information localizes source positions along lines of response. Cherenkov-radiator-integrated microchannel-plate photomultiplier tubes have achieved 30 ps TOF resolution,…

In this contribution we describe a novel solution for the construction of Positron Emission Tomograph. We present the device allowing for determination of the impact position as well as time and deph of interaction of the annihilation gamma…

Medical Physics · Physics 2013-10-15 P. Moskal , P. Salabura , M. Silarski , J. Smyrski , J. Zdebik , M. Zieliński

PET is an established medical diagnostic imaging method. Continuous improvements are aimed at refining image reconstruction, reducing the amount of radioactive tracer and combining with targeted therapy. TOF-PET provides the localization of…

Medical Physics · Physics 2021-11-17 Tomasz Matulewicz

Currently inorganic scintillator detectors are used in all commercial Time of Flight Positron Emission Tomograph (TOF-PET) devices. The J-PET collaboration investigates a possibility of construction of a PET scanner from plastic…

Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Jie Sun , Junyan Zhang , Qian Xia , Chuanfu Sun , Yumei Chen , Yunjie Yang , Huafeng Liu , Wentao Zhu , Qiegen Liu

We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…

J-PET is the first positron-emission tomograph (PET) constructed from plastic scintillators. It was optimized for the detection of photons from electron-positron annihilation. Such photons, having an energy of 511 keV, interact with…

Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…

Images from Positron Emission Tomography (PET) deliver functional data such as perfusion and metabolism. On the other hand, images from Magnetic Resonance Imaging (MRI) provide information describing anatomical structures. Fusing the…

Image and Video Processing · Electrical Eng. & Systems 2018-06-19 Hiliwi Leake Kidane , Stephanie Bricq , Alain Lalande

We have used the TOPAS Geant4-based package to create a parametric simulation of a new TOF-PET scanner design based on a low atomic number scintillator. TOPAS was extended to provide complete information on individual particle position,…

Medical Physics · Physics 2023-10-03 Kepler Domurat-Sousa , Cameron Poe