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This paper describes Simpson's paradox, and explains its serious implications for randomised control trials. In particular, we show that for any number of variables we can simulate the result of a controlled trial which uniformly points to…

Methodology · Statistics 2019-12-04 Norman Fenton , Martin Neil , Anthony Constantinou

A unified framework is proposed for tests of unobserved heterogeneity in parametric statistic models based on Neyman's $C(\alpha)$ approach. Such tests are irregular in the sense that the first order derivative of the log likelihood with…

Statistics Theory · Mathematics 2014-10-07 Jiaying Gu

Inferring causal effects of treatments is a central goal in many disciplines. The potential outcomes framework is a main statistical approach to causal inference, in which a causal effect is defined as a comparison of the potential outcomes…

Methodology · Statistics 2018-01-04 Peng Ding , Fan Li

In his seminal 1923 work, Neyman studied the variance estimation problem for the difference-in-means estimator of the average treatment effect in completely randomized experiments. He proposed a variance estimator that is conservative in…

Methodology · Statistics 2025-07-01 Ambarish Chattopadhyay , Guido W. Imbens

Identification of standard mediated effects such as the natural indirect effect relies on heavy causal assumptions. By circumventing such assumptions, so-called randomized interventional indirect effects have gained popularity in the…

Methodology · Statistics 2023-10-03 Caleb H. Miles

There are two general views in causal analysis of experimental data: the super population view that the units are an independent sample from some hypothetical infinite populations, and the finite population view that the potential outcomes…

Statistics Theory · Mathematics 2017-03-01 Peng Ding , Xinran Li , Luke W. Miratrix

Nonignorable missingness and noncompliance can occur even in well-designed randomized experiments making the intervention effect that the experiment was designed to estimate nonidentifiable. Nonparametric causal bounds provide a way to…

Statistics Theory · Mathematics 2020-10-13 Erin E. Gabriel , Arvid Sjölander , Michael C. Sachs

We consider the problem of detecting causal relationships between discrete time series, in the presence of potential confounders. A hypothesis test is introduced for identifying the temporally causal influence of $(x_n)$ on $(y_n)$,…

Methodology · Statistics 2023-11-20 A. Theocharous , G. G. Gregoriou , P. Sapountzis , I. Kontoyiannis

This paper is concerned with the well known Jeffreys-Lindley paradox. In a Bayesian set up, the so-called paradox arises when a point null hypothesis is tested and an objective prior is sought for the alternative hypothesis. In particular,…

Statistics Theory · Mathematics 2015-03-16 Cristiano Villa , Stephen Walker

The Neyman-Fisher controversy considered here originated with the 1935 presentation of Jerzy Neyman's Statistical Problems in Agricultural Experimentation to the Royal Statistical Society. Neyman asserted that the standard ANOVA F-test for…

Methodology · Statistics 2014-09-10 Arman Sabbaghi , Donald B. Rubin

Jeffreys-Lindley paradox is a case where frequentist and Bayesian hypothesis testing methodologies contradict with each other. This has caused confusion among data analysts for selecting a methodology for their statistical inference tasks.…

Other Statistics · Statistics 2025-03-20 Priyantha Wijayatunga

Causal inference, as a major research area in statistics and data science, plays a central role across diverse fields such as medicine, economics, education, and the social sciences. Design-based causal inference begins with randomized…

Methodology · Statistics 2025-12-01 Xin Lu , Wanjia Fu , Hongzi Li , Haoyang Yu , Honghao Zhang , Ke Zhu , Hanzhong Liu

The Jeffreys-Lindley paradox displays how the use of a p-value (or number of standard deviations z) in a frequentist hypothesis test can lead to an inference that is radically different from that of a Bayesian hypothesis test in the form…

Methodology · Statistics 2017-02-14 Robert D. Cousins

Many outcomes of interest in the social and health sciences, as well as in modern applications in computational social science and experimentation on social media platforms, are ordinal and do not have a meaningful scale. Causal analyses…

Methodology · Statistics 2015-01-07 Alexander Volfovsky , Edoardo M. Airoldi , Donald B. Rubin

Causal inference from observational data provides strong evidence for the best action in decision-making without performing expensive randomized trials. The effect of an action is usually not identifiable under unobserved confounding, even…

Machine Learning · Computer Science 2026-02-02 Md Musfiqur Rahman , Ziwei Jiang , Hilaf Hasson , Murat Kocaoglu

A key challenge in causal inference from observational studies is the identification and estimation of causal effects in the presence of unmeasured confounding. In this paper, we introduce a novel approach for causal inference that…

Methodology · Statistics 2022-10-17 Ying Zhou , Dingke Tang , Dehan Kong , Linbo Wang

Understanding how much each variable contributes to an outcome is a central question across disciplines. A causal view of explainability is favorable for its ability in uncovering underlying mechanisms and generalizing to new contexts.…

Methodology · Statistics 2026-03-09 Weihan Zhang , Zijun Gao

There is a well-known problem in Null Hypothesis Significance Testing: many statistically significant results fail to replicate in subsequent experiments. We show that this problem arises because standard `point-form null' significance…

Methodology · Statistics 2025-02-06 Fintan Costello , Paul Watts

Since its introduction by Fisher, the method of hypothesis testing that relies on computing error probabilities has witnessed several developments. Perhaps the most significant development was the seminal contributions of Neyman and Pearson…

Other Statistics · Statistics 2026-05-08 Reason Machete

In panel experiments, we randomly assign units to different interventions, measuring their outcomes, and repeating the procedure in several periods. Using the potential outcomes framework, we define finite population dynamic causal effects…

Methodology · Statistics 2021-05-28 Iavor Bojinov , Ashesh Rambachan , Neil Shephard