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Machine Learning (ML) has garnered considerable attention from researchers and practitioners as a new and adaptable tool for disease diagnosis. With the advancement of ML and the proliferation of papers and research in this field, a…

Machine Learning · Computer Science 2022-01-11 Md Manjurul Ahsan , Zahed Siddique

Purpose: To improve repeatability and reproducibility across acquisition parameters and reduce bias in quantitative susceptibility mapping (QSM) of the liver, through development of an optimized regularized reconstruction algorithm for…

Globally, the number of obese patients has doubled due to sedentary lifestyles and improper dieting. The tremendous increase altered human genetics, and health. According to the world health organization, Life expectancy dropped from 80 to…

Quantitative Methods · Quantitative Biology 2022-08-08 Amin Gasmi

Liver cirrhosis is an insidious condition involving the substitution of normal liver tissue with fibrous scar tissue and causing major health complications. The conventional method of diagnosis using liver biopsy is invasive and, therefore,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Kapil Kashyap , Sean Fargose , Chrisil Dabre , Fatema Dolaria , Nilesh Patil , Aniket Kore

Quantifiable image patterns associated with disease progression and treatment response are critical tools for guiding individual treatment, and for developing novel therapies. Here, we show that unsupervised machine learning can identify a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Matthias Perkonigg , Nina Bastati , Ahmed Ba-Ssalamah , Peter Mesenbrink , Alexander Goehler , Miljen Martic , Xiaofei Zhou , Michael Trauner , Georg Langs

Metabolomic data can potentially enable accurate, non-invasive and low-cost prediction of coronary artery disease. Regression-based analytical approaches however might fail to fully account for interactions between metabolites, rely on a…

MixRx uses Large Language Models (LLMs) to classify drug combination interactions as Additive, Synergistic, or Antagonistic, given a multi-drug patient history. We evaluate the performance of 4 models, GPT-2, Mistral Instruct 2.0, and the…

Other Quantitative Biology · Quantitative Biology 2026-01-08 Risha Surana , Cameron Saidock , Hugo Chacon

Motivated by two case studies using primary care records from the Clinical Practice Research Datalink, we describe statistical methods that facilitate the analysis of tall data, with very large numbers of observations. Our focus is on…

Methodology · Statistics 2018-05-14 Kirsty Rhodes , Rebecca Turner , Rupert Payne , Ian White

Large Language Models (LLMs) and causal learning each hold strong potential for clinical decision making (CDM). However, their synergy remains poorly understood, largely due to the lack of systematic benchmarks evaluating their integration…

Machine Learning · Computer Science 2025-11-14 Linna Wang , Zhixuan You , Qihui Zhang , Jiunan Wen , Ji Shi , Yimin Chen , Yusen Wang , Fanqi Ding , Ziliang Feng , Li Lu

Existing statistical methods for the analysis of micro-randomized trials (MRTs) are designed to estimate causal excursion effects using data from a single MRT. In practice, however, researchers can often find previous MRTs that employ…

Methodology · Statistics 2025-05-13 Easton Huch , Inbal Nahum-Shani , Lindsey Potter , Cho Lam , David W. Wetter , Walter Dempsey

Training data is the key component in designing algorithms for medical image analysis and in many cases it is the main bottleneck in achieving good results. Recent progress in image generation has enabled the training of neural network…

Computer Vision and Pattern Recognition · Computer Science 2018-11-02 Avi Ben-Cohen , Roey Mechrez , Noa Yedidia , Hayit Greenspan

MicroRNAs play critical roles in many physiological processes. Their dysregulations are also closely related to the development and progression of various human diseases, including cancer. Therefore, identifying new microRNAs that are…

Quantitative Methods · Quantitative Biology 2016-06-02 Claude Pasquier , Julien Gardès

Causal inference concerns the identification of cause-effect relationships between variables. However, often only linear combinations of variables constitute meaningful causal variables. For example, recovering the signal of a cortical…

One of the important techniques of Data mining is Classification. Many real world problems in various fields such as business, science, industry and medicine can be solved by using classification approach. Neural Networks have emerged as an…

Machine Learning · Computer Science 2011-10-13 K. Usha Rani

There have been reports of correlation between estimates of prevalence and test accuracy across studies included in diagnostic meta-analyses. It has been hypothesized that this unexpected association arises because of certain biases…

Methodology · Statistics 2025-08-15 Yang Lu , Robert Platt , Nandini Dendukuri

Heart disease is one of the significant challenges in today's world and one of the leading causes of many deaths worldwide. Recent advancement of machine learning (ML) application demonstrates that using electrocardiogram (ECG) and patient…

Machine Learning · Computer Science 2021-12-14 Md Manjurul Ahsan , Zahed Siddique

Machine learning (ML) offers a collection of powerful approaches for detecting and modeling associations, often applied to data having a large number of features and/or complex associations. Currently, there are many tools to facilitate…

Despite the successes of deep learning techniques at detecting objects in medical images, false positive detections occur which may hinder an accurate diagnosis. We propose a technique to reduce false positive detections made by a neural…

Image and Video Processing · Electrical Eng. & Systems 2021-01-27 Ishaan Bhat , Hugo J. Kuijf , Veronika Cheplygina , Josien P. W. Pluim

Several researchers have experimentally shown that substantial improvements can be obtained in difficult pattern recognition problems by combining or integrating the outputs of multiple classifiers. This chapter provides an analytical…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Kagan Tumer , Joydeep Ghosh

The process of data mining produces various patterns from a given data source. The most recognized data mining tasks are the process of discovering frequent itemsets, frequent sequential patterns, frequent sequential rules and frequent…

Databases · Computer Science 2014-02-13 Thabet Slimani , Amor Lazzez