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In today's world, a massive amount of data is available in almost every sector. This data has become an asset as we can use this enormous amount of data to find information. Mainly health care industry contains many data consisting of…

Machine Learning · Computer Science 2022-03-10 Hafsa Binte Kibria , Abdul Matin

This paper attempts multi-label classification by extending the idea of independent binary classification models for each output label, and exploring how the inherent correlation between output labels can be used to improve predictions.…

Machine Learning · Computer Science 2015-11-26 Amit Garg , Jonathan Noyola , Romil Verma , Ashutosh Saxena , Aditya Jami

Objective: Fluoropyrimidines are widely prescribed for colorectal and breast cancers, but are associated with toxicities such as hand-foot syndrome and cardiotoxicity. Since toxicity documentation is often embedded in clinical notes, we…

Computation and Language · Computer Science 2025-10-24 Xizhi Wu , Madeline S. Kreider , Philip E. Empey , Chenyu Li , Yanshan Wang

Understanding the progression of cancer is crucial for defining treatments for patients. The objective of this study is to automate the detection of metastatic liver disease from free-style computed tomography (CT) radiology reports. Our…

Machine Learning · Computer Science 2023-10-31 Maede Ashofteh Barabadi , Xiaodan Zhu , Wai Yip Chan , Amber L. Simpson , Richard K. G. Do

The composite likelihood (CL) is amongst the computational methods used for estimation of the generalized linear mixed model (GLMM) in the context of bivariate meta-analysis of diagnostic test accuracy studies. Its advantage is that the…

Methodology · Statistics 2018-07-12 Aristidis K. Nikoloulopoulos

For many conditions, it is of clinical importance to know not just the ability of a test to distinguish between those with and without the disease, but also the sensitivity to detect disease at different stages: in particular, the test's…

Methodology · Statistics 2026-02-10 Efthymia Derezea , Nicky J Welton , Gabriel Rogers , Hayley E Jones

The state-of-the-art cardiovascular disease diagnosis techniques use machine-learning algorithms based on feature extraction and classification. In this work, in contrast to a conventional single Electrocardiogram (ECG) lead, two leads are…

Signal Processing · Electrical Eng. & Systems 2023-05-26 Cheng Guo , Sajid Ahmed , Mohamed-Slim Alouini

Recent advances in experimental methods have enabled researchers to collect data on thousands of analytes simultaneously. This has led to correlational studies that associated molecular measurements with diseases such as Alzheimer's, Liver,…

Quantitative Methods · Quantitative Biology 2024-05-20 Divyagna Bavikadi , Ayushi Agarwal , Shashank Ganta , Yunro Chung , Lusheng Song , Ji Qiu , Paulo Shakarian

In regression models for categorical data a linear model is typically related to the response variables via a transformation of probabilities called the link function. We introduce an approach based on two link functions for binary data…

Methodology · Statistics 2016-11-04 Monia Lupparelli , Alberto Roverato

Computer-aided diagnosis (CAD) technology can assist clinicians in evaluating liver lesions and intervening with treatment in time. Although CAD technology has advanced in recent years, the application scope of existing datasets remains…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Zhe Liu , Kai Han , Siqi Ma , Yan Zhu , Jun Chen , Chongwen Lyu , Xinyi Qiu , Chengxuan Qian , Yuqing Song , Yi Liu , Liyuan Tian , Yang Ji , Yuefeng Li

Transfer learning and joint learning approaches are extensively used to improve the performance of Convolutional Neural Networks (CNNs). In medical imaging applications in which the target dataset is typically very small, transfer learning…

Image and Video Processing · Electrical Eng. & Systems 2020-05-26 Michal Heker , Hayit Greenspan

3\b{eta}-O-phthalic ester of betulinic acid is of great importance in anticancer studies. However, the optimization of its reaction conditions requires a large number of experimental works. To simplify the number of times of optimization in…

Machine Learning · Computer Science 2015-11-13 Run Wang , Qiaoli Mo , Qian Zhang , Fudi Chen , Dazuo Yang

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) affects 30-40% of US adults and is the most common chronic liver disease. Although often asymptomatic, progression can lead to cirrhosis. The objective of the…

Machine Learning · Computer Science 2026-04-13 Mary E. An , Paul M. Griffin , Jonathan G. Stine , Balakrishnan S. Ramakrishna , Soundar R. T. Kumara

We exploit liver cancer prediction model using machine learning algorithms based on epidemiological data of over 55 thousand peoples from 2014 to the present. The best performance is an AUC of 0.71. We analyzed model parameters to…

Machine Learning · Computer Science 2021-02-04 Jinpeng Li , Yaling Tao , Ting Cai

Kidneys are the filter of the human body. About 10% of the global population is thought to be affected by Chronic Kidney Disease (CKD), which causes kidney function to decline. To protect in danger patients from additional kidney damage,…

Mammography is the most effective and available tool for breast cancer screening. However, the low positive predictive value of breast biopsy resulting from mammogram interpretation leads to approximately 70% unnecessary biopsies with…

Machine Learning · Computer Science 2013-06-04 Sahar A. Mokhtar , Alaa. M. Elsayad

There is growing interest in exploring causal effects in target populations via data combination. However, most approaches are tailored to specific settings and lack comprehensive comparative analyses. In this article, we focus on a typical…

Methodology · Statistics 2024-09-17 Peng Wu , Shanshan Luo , Zhi Geng

Supervised machine learning classifiers sometimes face challenges related to the performance, accuracy, or overfitting. This paper introduces the Artificial Liver Classifier (ALC), a novel supervised learning model inspired by the human…

Artificial Intelligence · Computer Science 2025-09-24 Mahmood A. Jumaah , Yossra H. Ali , Tarik A. Rashid

Machine learning has been successfully used in critical domains, such as medicine. However, extracting meaningful insights from biomedical data is often constrained by the lack of their available disease labels. In this research, we…

Quantitative Methods · Quantitative Biology 2025-04-02 Hido Pinto , Eran Segal

Progression to dialysis or end-stage renal disease is a rare but clinically important outcome. Clinicians need evidence on how medication exposures influence downstream risk. We constructed a fixed-window EHR cohort (90-day observation,…

Machine Learning · Computer Science 2026-04-28 Kalyani P. Pande , Evan Yang , Bryan Zhu , Sandeep K. Mallipattu , Alisa Yurovsky , Tengfei Ma