Related papers: Synaptotagmin 7 Functions as a Ca2+-sensor for Syn…
Many proteins undergo conformational changes during their activity. A full understanding of the function of these proteins can only be obtained if different conformations and transitions between them can be monitored in aqueous solution,…
Weakly Supervised Semantic Segmentation (WSSS) is challenging, particularly when image-level labels are used to supervise pixel level prediction. To bridge their gap, a Class Activation Map (CAM) is usually generated to provide pixel level…
Objective: We develop a channel-adaptive (CA) architecture that seamlessly processes multi-variate time-series with an arbitrary number of channels, and in particular intracranial electroencephalography (iEEG) recordings. Methods: Our CA…
We present a simple biophysical model for the coupling between synaptic transmission and the local calcium concentration on an enveloping astrocytic domain. This interaction enables the astrocyte to modulate the information flow from…
Neurotransmitter receptor molecules, concentrated in postsynaptic domains along with scaffold and a number of other molecules, are key regulators of signal transmission across synapses. Employing experiment and theory, we develop a…
In this paper we present a biologically detailed mathematical model of tripartite synapses, where astrocytes modulate short-term synaptic plasticity. The model consists of a pre-synaptic bouton, a post-synaptic dendritic spine-head, a…
Neuromodulatory receptors in presynaptic position have the ability to suppress synaptic transmission for seconds to minutes when fully engaged. This effectively alters the synaptic strength of a connection. Much work on neuromodulation has…
Recent advances on the Vector Space Model have significantly improved some NLP applications such as neural machine translation and natural language generation. Although word co-occurrences in context have been widely used in…
Due to many limitations of Von Neumann architecture such as speed, memory bandwidth, efficiency of global interconnects and increase in the application of artificial neural network, researchers have been pushed to look into alternative…
Deep cognitive attention is characterized by heightened gamma oscillations and coordinated visual behavior. Despite the physiological importance of these mechanisms, computational studies rarely synthesize these modalities or identify the…
Intracellular bidirectional transport of cargo on microtubule filaments is achieved by the collective action of oppositely directed dynein and kinesin motors. Experiments have found that in certain cases, inhibiting the activity of one type…
Cortical sensory neurons are known to be highly variable, in the sense that responses evoked by identical stimuli often change dramatically from trial to trial. The origin of this variability is uncertain, but it is usually interpreted as…
Sensory stimuli can be recognized more rapidly when they are expected. This phenomenon depends on expectation affecting the cortical processing of sensory information. However, virtually nothing is known on the mechanisms responsible for…
There is considerable interest in the pH-dependent switchable biocatalytic properties of cerium oxide nanoparticles (CeNPs) in biomedicine, where these materials exhibit beneficial antioxidant activity against reactive oxygen species at…
Integrated sensing and communication (ISAC) technology is vital for vehicular networks, yet the time-varying communication channels and rapid movement of targets present significant challenges for real-time precoding design. Traditional…
Visual prostheses hold great promise for restoring vision in blind individuals. While researchers have successfully utilized M/EEG signals to evoke visual perceptions during the brain decoding stage of visual prostheses, the complementary…
The thermal cis-trans isomerization around the C$_{13}$=C$_{14}$ double bond of retinal is a prototypical high-barrier reaction whose mechanism hinges on subtle out-of-plane bending motions. We apply Artificial Intelligence for Molecular…
Learning and logic are fundamental brain functions that make the individual to adapt to the environment, and such functions are established in human brain by modulating ionic fluxes in synapses. Nanoscale ionic/electronic devices with…
The activation of the dodecameric Ca2+/calmodulin dependent kinase II (CaMKII) holoenzyme is critical for the formation of memory. We now report that CaMKII has a remarkable property, which is that activation of the holoenzyme triggers the…
In the quest of green energy, Solid Oxide Fuel Cells (SOFC) have drawn considerable attention for chemical-to-electric energy conversion. In the present paper, we report an enhancement of ionic conductivity in Cu2P2-xVxO7 by vanadium…