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Multivariate time-series data are frequently observed in critical care settings and are typically characterized by sparsity (missing information) and irregular time intervals. Existing approaches for learning representations in this domain…

Machine Learning · Computer Science 2022-02-17 Sindhu Tipirneni , Chandan K. Reddy

In oncology the efficacy of novel therapeutics often differs across patient subgroups, and these variations are difficult to predict during the initial phases of the drug development process. The relation between the power of randomized…

Methodology · Statistics 2025-06-05 Boyu Ren , Federico Ferrari , Sandra Fortini , Steffen Ventz , Lorenzo Trippa

Real-world deployment of machine learning models is challenging because data evolves over time. While no model can work when data evolves in an arbitrary fashion, if there is some pattern to these changes, we might be able to design methods…

Machine Learning · Computer Science 2024-05-03 Rasool Fakoor , Jonas Mueller , Zachary C. Lipton , Pratik Chaudhari , Alexander J. Smola

Atrial fibrillation (AF) detection from electrocardiogram (ECG) signals is crucial for early diagnosis and management of cardiovascular diseases. However, deploying robust AF detection models across different datasets with significant…

Signal Processing · Electrical Eng. & Systems 2025-03-19 Majid Soleimani , Maedeh H. Toosi , Siamak Mohammadi , Babak Hossein Khalaj

We present a novel approach for adaptive, differentiable parameterization of large-scale random fields. If the approach is coupled with any gradient-based optimization algorithm, it can be applied to a variety of optimization problems,…

Machine Learning · Computer Science 2020-06-09 Maksim Elizarev , Andrei Mukhin , Aleksey Khlyupin

Understanding the temporal properties of longitudinal data is critical for identifying trends, predicting future events, and making informed decisions in any field where temporal data is analysed, including health and epidemiology, finance,…

Because protein-protein interactions (PPIs) are crucial to understand living systems, harvesting these data is essential to probe disease development and discern gene/protein functions and biological processes. Some curated datasets contain…

Biomolecules · Quantitative Biology 2024-03-12 Gilchan Park , Sean McCorkle , Carlos Soto , Ian Blaby , Shinjae Yoo

Given two distinct subsets $A,B$ in the state space of some dynamical system, Transition Path Theory (TPT) was successfully used to describe the statistical behavior of transitions from $A$ to $B$ in the ergodic limit of the stationary…

Dynamical Systems · Mathematics 2020-11-03 Luzie Helfmann , Enric Ribera Borrell , Christof Schütte , Péter Koltai

We study sparse principal component analysis for high dimensional vector autoregressive time series under a doubly asymptotic framework, which allows the dimension $d$ to scale with the series length $T$. We treat the transition matrix of…

Machine Learning · Statistics 2013-07-02 Zhaoran Wang , Fang Han , Han Liu

A pulsar timing array (PTA) refers to a program of regular, high-precision timing observations of a widely distributed array of millisecond pulsars. Here we review the status of the three primary PTA projects and the joint International…

Instrumentation and Methods for Astrophysics · Physics 2019-04-03 George Hobbs , Shi Dai

Dimension reduction is useful for exploratory data analysis. In many applications, it is of interest to discover variation that is enriched in a "foreground" dataset relative to a "background" dataset. Recently, contrastive principal…

Methodology · Statistics 2021-05-04 Didong Li , Andrew Jones , Barbara Engelhardt

The detection of a gravitational wave background in the nano-Hertz frequency range from Pulsar Timing Array (PTA) observations offers new insights into evolution of the early universe. In this work we analyze gravitational wave data from…

High Energy Physics - Phenomenology · Physics 2025-05-16 Jinzheng Li , Pran Nath

Test-Time Adaptation (TTA) enables pre-trained models to adjust to distribution shift by learning from unlabeled test-time streams. However, existing methods typically treat these streams as independent samples, overlooking the supervisory…

Machine Learning · Computer Science 2026-01-30 Young Kyung Kim , Oded Schlesinger , Qiangqiang Wu , J. Matías Di Martino , Guillermo Sapiro

Principal Component Analysis (PCA) and K-means constitute fundamental techniques in multivariate analysis. Although they are frequently applied independently or sequentially to cluster observations, the relationship between them, especially…

Machine Learning · Statistics 2025-12-02 Victor Saquicela , Kenneth Palacio-Baus , Mario Chifla

Analysing human gait has found considerable interest in recent computer vision research. So far, however, contributions to this topic exclusively dealt with the tasks of person identification or activity recognition. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2010-04-28 Rohit Katiyar , Dr. Vinay Kumar Pathak

Pulsar timing is a technique that uses the highly stable spin periods of neutron stars to investigate a wide range of topics in physics and astrophysics. Pulsar timing arrays (PTAs) use sets of extremely well-timed pulsars as a Galaxy-scale…

Instrumentation and Methods for Astrophysics · Physics 2021-10-05 J. P. W. Verbiest , S. Oslowski , S. Burke-Spolaor

Notable progress has been made in generalist medical large language models across various healthcare areas. However, large-scale modeling of in-hospital time series data - such as vital signs, lab results, and treatments in critical care -…

Principal component analysis (PCA) is a classical dimension reduction method which projects data onto the principal subspace spanned by the leading eigenvectors of the covariance matrix. However, it behaves poorly when the number of…

Statistics Theory · Mathematics 2013-05-27 Zongming Ma

Principal component analysis (PCA) is a dimensionality reduction method in data analysis that involves diagonalizing the covariance matrix of the dataset. Recently, quantum algorithms have been formulated for PCA based on diagonalizing a…

Quantum Physics · Physics 2022-10-26 Max Hunter Gordon , M. Cerezo , Lukasz Cincio , Patrick J. Coles

In recent times, functional data analysis (FDA) has been successfully applied in the field of high dimensional data classification. In this paper, we present a novel classification framework using functional data and classwise Principal…

Machine Learning · Statistics 2021-06-29 Avishek Chatterjee , Satyaki Mazumder , Koel Das