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We consider a continuous-time Markov chain model of SIR disease dynamics with two levels of mixing. For this so-called stochastic households model, we provide two methods for inferring the model parameters---governing within-household…

Populations and Evolution · Quantitative Biology 2018-02-07 James N. Walker , Joshua V. Ross , Andrew J. Black

Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it…

Populations and Evolution · Quantitative Biology 2024-01-30 Laura Di Domenico , Eugenio Valdano , Vittoria Colizza

A stochastic epidemic model is defined in which each individual belongs to a household, a secondary grouping (typically school or workplace) and also the community as a whole. Moreover, infectious contacts take place in these three settings…

Applications · Statistics 2009-08-17 Tom Britton , Theodore Kypraios , Philip O'Neill

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

We study the problem of identifying infection sources in a network based on the network topology, and a subset of infection timestamps. In the case of a single infection source in a tree network, we derive the maximum likelihood estimator…

Social and Information Networks · Computer Science 2019-03-06 Wenchang Tang , Feng Ji , Wee Peng Tay

Human to human transmissible infectious diseases spread in a population using human interactions as its transmission vector. The early stages of such an outbreak can be modeled by a graph whose edges encode these interactions between…

Populations and Evolution · Quantitative Biology 2020-06-11 Goncalo Oliveira

Inferring how an epidemic will progress and what actions to take when presented with limited information is of critical importance for epidemiologists and health professionals. In real world settings, epidemiology data can be scarce or…

Computation · Statistics 2022-11-02 Georgios Efstathiadis

Capturing the structure of a population and characterising contacts within the population are key to reliable projections of infectious disease. Two main elements of population structure -- contact heterogeneity and age -- have been…

Physics and Society · Physics 2025-03-17 Luke Murray Kearney , Emma L. Davis , Matt J. Keeling

Two crucial elements facilitate the understanding and control of communicable disease spread within a social setting. These components are, the underlying contact structure among individuals that determines the pattern of disease…

Populations and Evolution · Quantitative Biology 2013-05-29 Pierre-Andre Noel , Bahman Davoudi , Louis J. Dube , Robert C. Brunham , Babak Pourbohloul

We develop a stochastic epidemic model progressing over dynamic networks, where infection rates are heterogeneous and may vary with individual-level covariates. The joint dynamics are modeled as a continuous-time Markov chain such that…

Methodology · Statistics 2021-12-16 Fan Bu , Allison E. Aiello , Alexander Volfovsky , Jason Xu

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

Mathematical models represent one of the fundamental ways of studying nature. In special, epidemic models have shown to be particularly useful in the understanding of the course of diseases and in the planning effective control policies. A…

Physics and Society · Physics 2022-10-19 Paulo C. Ventura , Eric K. Tokuda , Luciano da F. Costa , Francisco A. Rodrigues

We present a contact-based model to study the spreading of epidemics by means of extending the dynamic message passing approach to temporal networks. The shift in perspective from node- to edge-centric quantities enables accurate modelling…

Physics and Society · Physics 2019-08-07 Andreas Koher , Hartmut H. K. Lentz , James P. Gleeson , Philipp Hövel

Tracking the spread of infectious disease during a pandemic has posed a great challenge to the governments and health sectors on a global scale. To facilitate informed public health decision-making, the concerned parties usually rely on…

Methodology · Statistics 2023-06-05 Tejasv Bedi , Yanxun Xu , Qiwei Li

When an unprecedented infectious disease with high mortality and transmissibility emerges, immediate usage of vaccines or medicines is hardly available. Thus, many health authorities rely on non-pharmaceutical interventions through…

Physics and Society · Physics 2022-01-21 Minsuk Kim , Soon-Hyung Yook

The modeling of the spreading of communicable diseases has experienced significant advances in the last two decades or so. This has been possible due to the proliferation of data and the development of new methods to gather, mine and…

Physics and Society · Physics 2020-09-09 Alberto Aleta , Guilherme Ferraz de Arruda , Yamir Moreno

Infectious or contagious diseases can be transmitted from one person to another through social contact networks. In today's interconnected global society, such contagion processes can cause global public health hazards, as exemplified by…

Social and Information Networks · Computer Science 2020-07-30 Anirban Dasgupta , Srijan Sengupta

Exploiting pathogen genomes to reconstruct transmission represents a powerful tool in the fight against infectious disease. However, their interpretation rests on a number of simplifying assumptions that regularly ignore important…

Populations and Evolution · Quantitative Biology 2017-02-08 Nicola De Maio , Chieh-Hsi Wu , Daniel J Wilson

The spatial structure of populations is a key element in the understanding of the large scale spreading of epidemics. Motivated by the recent empirical evidence on the heterogeneous properties of transportation and commuting patterns among…

Populations and Evolution · Quantitative Biology 2008-03-19 Vittoria Colizza , Alessandro Vespignani

Intuitively, sampling is likely to be more efficient for prevalence estimation, if the cases (or positives) have a relatively higher representation in the sample than in the population. In case the virus is transmitted via personal…

Applications · Statistics 2020-11-18 Li-Chun Zhang