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Given a set of integers, one can easily construct the set of their pairwise distances. We consider the inverse problem: given a set of pairwise distances, find the integer set which realizes the pairwise distance set. This problem arises in…

Discrete Mathematics · Computer Science 2012-12-12 Kishore Jaganathan , Babak Hassibi

Understanding the evolution of a set of genes or species is a fundamental problem in evolutionary biology. The problem we study here takes as input a set of trees describing {possibly discordant} evolutionary scenarios for a given set of…

Data Structures and Algorithms · Computer Science 2019-07-10 Cedric Chauve , Mark Jones , Manuel Lafond , Céline Scornavacca , Mathias Weller

We show that the Subgroup distance problem regarding the Hamming distance, the Cayley distance and the $l_\infty$ distance is NP-complete when the input group is cyclic. When we restrict the $l_\infty$ distance to fixed values we show that…

Group Theory · Mathematics 2026-02-20 Andreas Rosowski

Restrictions to molecular motion by barriers (membranes) are ubiquitous in biological tissues, porous media and composite materials. A major challenge is to characterize the microstructure of a material or an organism nondestructively using…

Soft Condensed Matter · Physics 2011-03-11 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern

The dictionary learning problem concerns the task of representing data as sparse linear sums drawn from a smaller collection of basic building blocks. In application domains where such techniques are deployed, we frequently encounter…

Signal Processing · Electrical Eng. & Systems 2021-07-21 Yong Sheng Soh

We study the isoperimetric profiles of certain families of finitely generated groups defined via marked Schreier graphs and permutation wreath products. The groups we study are among the "simplest" examples within a much larger class of…

Probability · Mathematics 2015-10-30 Laurent Saloff-Coste , Tianyi Zheng

In the context of the genome rearrangement problem, we analyze two well known models, namely the reversal and the prefix reversal models, by exploiting the connection with the notion of permutation pattern. More specifically, for any $k$,…

Combinatorics · Mathematics 2019-03-22 Giulio Cerbai , Luca Ferrari

The Darwinian paradigm of biological evolution is based on the separability of the variation and selection processes. As a result, the population thinking had always been an integral part of the Darwinian approach. I propose an alternative…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Vasily Ogryzko

We use subgroup distortion to determine the rate of escape of a simple random walk on a class of polycyclic groups, and we show that the rate of escape is invariant under changes of generating set for these groups. For metabelian groups, we…

Probability · Mathematics 2011-09-14 Russ Thompson

Radical shifts in the genetic composition of large cell populations are rare events with quite low probabilities, which direct numerical simulations generally fail to evaluate accurately. In this paper, we develop a theoretical large…

Probability · Mathematics 2024-09-16 Robert Azencott , Brett Geiger , Ilya Timofeyev

Phylogenetic inference-the derivation of a hypothesis for the common evolutionary history of a group of species- is an active area of research at the intersection of biology, computer science, mathematics, and statistics. One assumes the…

Populations and Evolution · Quantitative Biology 2016-06-21 Ruth Davidson , Joseph Rusinko , Zoe Vernon , Jing Xi

This paper discusses basic results and recent developments on variational regularization methods, as developed for inverse problems. In a typical setup we review basic properties needed to obtain a convergent regularization scheme and…

Machine Learning · Computer Science 2021-12-10 Martin Burger

In order to identify clusters of objects with features transformed by unknown affine transformations, we develop a Bayesian cluster process which is invariant with respect to certain linear transformations of the feature space and able to…

Methodology · Statistics 2016-12-01 Hsin-Hsiung Huang , Jie Yang

Group-invariant probability distributions appear in many data-generative models in machine learning, such as graphs, point clouds, and images. In practice, one often needs to estimate divergences between such distributions. In this work, we…

Machine Learning · Computer Science 2026-02-05 Behrooz Tahmasebi , Stefanie Jegelka

In the evolution of a genome, the gene sequence is sometimes rearranged, for example by transposition of two adjacent gene blocks. In biocombinatorics, one tries to reconstruct these rearrangement incidents from the resulting permutation.…

Combinatorics · Mathematics 2007-05-23 Henrik Eriksson , Kimmo Eriksson , Jonas Sjostrand

We extend the theory of fast Fourier transforms on finite groups to finite inverse semigroups. We use a general method for constructing the irreducible representations of a finite inverse semigroup to reduce the problem of computing its…

Group Theory · Mathematics 2011-08-02 Martin Malandro

We show that the recent experimental observation of the rectification of swimming bacteria in a system with an array of asymmetric barriers occurs due to the ballistic component of the bacteria trajectories introduced by the bacterial…

Soft Condensed Matter · Physics 2009-11-13 M. B. Wan , C. J. Olson Reichhardt , Z. Nussinov , C. Reichhardt

Inversion symmetry is a very non-trivial discrete symmetry of Frobenius manifolds. It was obtained by Dubrovin from one of the elementary Schlesinger transformations of a special ODE associated to a Frobenius manifold. In this paper, we…

Mathematical Physics · Physics 2013-04-19 P. Dunin-Barkowski , S. Shadrin , L. Spitz

Bacteria are known to exchange genetic information by horizontal gene transfer. Since the frequency of homologous recombination depends on the similarity of recombining segments, several studies examined whether this could lead to the…

Probability · Mathematics 2015-06-09 Sergey Pirogov , Aleksandre Rybko , Anastasia Kalinina , Mikhail Gelfand

Lateral gene transfer (LGT) is a common mechanism of non-vertical evolution where genetic material is transferred between two more or less distantly related organisms. It is particularly common in bacteria where it contributes to adaptive…

Probability · Mathematics 2012-06-18 Sebastien Roch , Sagi Snir