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The paper introduces scaled Bregman distances of probability distributions which admit non-uniform contributions of observed events. They are introduced in a general form covering not only the distances of discrete and continuous stochastic…

Information Theory · Computer Science 2021-05-12 Wolfgang Stummer , Igor Vajda

A common task in experimental sciences is to fit mathematical models to real-world measurements to improve understanding of natural phenomenon (reverse-engineering or inverse modeling). When complex dynamical systems are considered, such as…

Numerical Analysis · Mathematics 2018-06-18 Jean-Charles Croix , Nicolas Durrande , Mauricio Alvarez

Herein it is shown that in order to study the statistical properties of DNA sequences in bacterial chromosomes it suffices to consider only one half of the chromosome because they are similar to its corresponding complementary sequence in…

Genomics · Quantitative Biology 2009-11-10 Marco V. Jose , Tzipe Govezensky , Juan R. Bobadilla

Pathogen genome data offers valuable structure for spatial models, but its utility is limited by incomplete sequencing coverage. We propose a probabilistic framework for inferring genetic distances between unsequenced cases and known…

Genomics · Quantitative Biology 2025-09-10 Haley Stone , Jing Du , Hao Xue , Matthew Scotch , David Heslop , Andreas Züfle , Chandini Raina MacIntyre , Flora Salim

Breakpoint graphs are ubiquitous structures in the field of genome rearrangements. Their cycle decomposition has proved useful in computing and bounding many measures of (dis)similarity between genomes, and studying the distribution of…

Discrete Mathematics · Computer Science 2013-03-18 Simona Grusea , Anthony Labarre

We provide a class of diffusion processes for continuous time-varying multivariate angular data with explicit transition probability densities, enabling exact likelihood inference. The presented diffusions are time-reversible and can be…

Methodology · Statistics 2024-09-05 Eduardo García-Portugués , Michael Sørensen

The ability to estimate the evolutionary distance between extant genomes plays a crucial role in many phylogenomic studies. Often such estimation is based on the parsimony assumption, implying that the distance between two genomes can be…

Genomics · Quantitative Biology 2017-05-29 Nikita Alexeev , Max A. Alekseyev

Reconstructing training data from trained neural networks is an active area of research with significant implications for privacy and explainability. Recent advances have demonstrated the feasibility of this process for several data types.…

Machine Learning · Computer Science 2024-11-26 Ran Elbaz , Gilad Yehudai , Meirav Galun , Haggai Maron

In computational inverse problems, it is common that a detailed and accurate forward model is approximated by a computationally less challenging substitute. The model reduction may be necessary to meet constraints in computing time when…

Methodology · Statistics 2018-02-14 Daniela Calvetti , Matthew M. Dunlop , Erkki Somersalo , Andrew M. Stuart

A new Bayesian image segmentation algorithm is proposed by combining a loopy belief propagation with an inverse real space renormalization group transformation to reduce the computational time. In results of our experiment, we observe that…

Computer Vision and Pattern Recognition · Computer Science 2015-03-16 Kazuyuki Tanaka , Shun Kataoka , Muneki Yasuda , Masayuki Ohzeki

In a recent paper, Dave Benson and Peter Symonds defined a new invariant $\gamma_G(M)$ for a finite dimensional module $M$ of a finite group $G$ which attempts to quantify how close a module is to being projective. In this paper, we…

Representation Theory · Mathematics 2020-12-02 Aparna Upadhyay

The reconstruction problem for permutations on $n$ elements from their erroneous patterns which are distorted by transpositions is presented in this paper. It is shown that for any $n \geq 3$ an unknown permutation is uniquely…

Combinatorics · Mathematics 2007-05-23 Elena Konstantinova , Vladimir Levenshtein , Johannes Siemons

In the last years, algebraic tools have been proven useful in phylogenetic reconstruction and model selection through the study of phylogenetic invariants. However, up to now, the models studied from an algebraic viewpoint are either too…

Populations and Evolution · Quantitative Biology 2024-04-16 Marta Casanellas , Roser Homs Pons , Angélica Torres

Genome wide comparisons between enteric bacteria yield large sets of conserved putative regulatory sites on a gene by gene basis that need to be clustered into regulons. Using the assumption that regulatory sites can be represented as…

Biological Physics · Physics 2009-11-07 Erik van Nimwegen , Mihaela Zavolan , Nikolaus Rajewsky , Eric D. Siggia

The inversion distance, that is the distance between two unichromosomal genomes with the same content allowing only inversions of DNA segments, can be exactly computed thanks to a pioneering approach of Hannenhalli and Pevzner from 1995. In…

Data Structures and Algorithms · Computer Science 2019-10-01 Eyla Willing , Jens Stoye , Marília D. V. Braga

In this paper, we show that when two systems of differential equations admitting a symmetry group are related by a point transformation it is always possible to generate invariant schemes, one for each system, that are also related by the…

Mathematical Physics · Physics 2007-05-23 Francis Valiquette

During the past century, biologists and mathematicians investigated two mechanisms underlying bacteria motion: the run phase during which bacteria move in straight lines and the tumble phase in which they change their orientation. When…

Analysis of PDEs · Mathematics 2025-05-19 Alain Blaustein

In the context of the genome rearrangement problem, we analyze two well known models, namely the block transposition and the prefix block transposition models, by exploiting the connection with the notion of permutation pattern. More…

Combinatorics · Mathematics 2018-08-09 Giulio Cerbai , Luca Ferrari

Considering a pair of genomes, the goal of rearrangement distance problems is to estimate how distant these genomes are from each other based on genome rearrangements. Seminal works in genome rearrangements assumed that both genomes being…

Data Structures and Algorithms · Computer Science 2024-05-21 Alexsandro Oliveira Alexandrino

The aim of this paper is to provide an overview of recent development related to Bregman distances outside its native areas of optimization and statistics. We discuss approaches in inverse problems and image processing based on Bregman…

Optimization and Control · Mathematics 2015-05-21 Martin Burger