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Chemical mapping methods probe RNA structure by revealing and leveraging correlations of a nucleotide's structural accessibility or flexibility with its reactivity to various chemical probes. Pioneering work by Lucks and colleagues has…

Biomolecules · Quantitative Biology 2013-04-04 Matthew G. Seetin , Wipapat Kladwang , J. P. Bida , Rhiju Das

Multi-step or hybrid deepfakes, created by sequentially applying different deepfake creation methods such as Face-Swapping, GAN-based generation, and Diffusion methods, can pose an emerging and unforseen technical challenge for detection…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Minji Heo , Simon S. Woo

Motif finding is an important step for the detection of rare events occurring in a set of DNA or protein sequences. Extraction of information about these rare events can lead to new biological discoveries. Motifs are some important patterns…

Data Structures and Algorithms · Computer Science 2024-03-04 Saurav Dhar , Amlan Saha , Dhiman Goswami , Md. Abul Kashem Mia

Parallelization techniques have become ubiquitous for accelerating inference and training of deep neural networks. Despite this, several operations are still performed in a sequential manner. For instance, the forward and backward passes…

Machine Learning · Computer Science 2023-10-30 Federico Danieli , Miguel Sarabia , Xavier Suau , Pau Rodríguez , Luca Zappella

Limited spectrum coverage is a problem in shotgun proteomics. Replicates are generated to improve the spectrum coverage. When integrating peptide identification results obtained from replicates, the state-of-the-art algorithm PeptideProphet…

Quantitative Methods · Quantitative Biology 2012-12-04 Chao Yang , Zengyou He , Weichuan Yu

Fast Radio Bursts (FRBs) are mysterious bursts in the millisecond timescale at radio wavelengths. Currently, there is little understanding about the classification of repeating FRBs, based on difference in physics, which is of great…

High Energy Astrophysical Phenomena · Physics 2023-07-12 Bjorn Jasper R. Raquel , Tetsuya Hashimoto , Tomotsugu Goto , Bo Han Chen , Yuri Uno , Tiger Yu-Yang Hsiao , Seong Jin Kim , Simon C. -C. Ho

Meta-analysis is routinely performed in many scientific disciplines. This analysis is attractive since discoveries are possible even when all the individual studies are underpowered. However, the meta-analytic discoveries may be entirely…

Methodology · Statistics 2023-05-09 Marina Bogomolov , Ruth Heller

Fabricating experimental pictures in research work is a serious academic misconduct, which should better be detected in the reviewing process. However, due to large number of submissions, the detection whether a picture is fabricated or…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Binrui Shen , Qiang Niu , Shengxin Zhu

We propose a general and flexible procedure for testing multiple hypotheses about sequential (or streaming) data that simultaneously controls both the false discovery rate (FDR) and false nondiscovery rate (FNR) under minimal assumptions…

Methodology · Statistics 2019-01-14 Jay Bartroff , Jinlin Song

Despite the potential of synthetic medical data for augmenting and improving the generalizability of deep learning models, memorization in generative models can lead to unintended leakage of sensitive patient information and limit model…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Orhun Utku Aydin , Alexander Koch , Adam Hilbert , Jana Rieger , Felix Lohrke , Fujimaro Ishida , Satoru Tanioka , Dietmar Frey

When using LLMs to rank items based on given criteria, or evaluate answers, the order of candidate items can influence the model's final decision. This sensitivity to item positioning in a LLM's prompt is known as position bias. Prior…

Machine Learning · Computer Science 2025-07-25 Ali Vardasbi , Gustavo Penha , Claudia Hauff , Hugues Bouchard

The rapid development of high-throughput sequencing technologies has led to an explosive increase in biological sequence data, making sequence clustering a fundamental task in large-scale bioinformatics analyses. Unlike traditional…

Genomics · Quantitative Biology 2026-01-22 Simeng Zhang , Xinying Liu , Jun Lou , Mudi Jiang , Quan Zou , Zengyou He

This paper presents a new approach to statistical similarity assessment based on sequence alignment. The algorithm performs mutual matching of two random sequences by successively searching for common elements and by applying sequence…

Signal Processing · Electrical Eng. & Systems 2021-06-09 Jakub Nikonowicz , Łukasz Matuszewski , Paweł Kubczak

X-ray ptychography is one of the versatile techniques for nanometer resolution imaging. The magnitude of the diffraction patterns is recorded on a detector and the phase of the diffraction patterns is estimated using phase retrieval…

Image and Video Processing · Electrical Eng. & Systems 2021-05-21 Prasan Shedligeri , Florian Schiffers , Semih Barutcu , Pablo Ruiz , Aggelos K Katsaggelos , Oliver Cossairt

Typical fingerprint recognition systems are comprised of a spoof detection module and a subsequent recognition module, running one after the other. In this paper, we reformulate the workings of a typical fingerprint recognition system. In…

Computer Vision and Pattern Recognition · Computer Science 2021-07-26 Additya Popli , Saraansh Tandon , Joshua J. Engelsma , Naoyuki Onoe , Atsushi Okubo , Anoop Namboodiri

In this paper we describe a new method for detecting and counting a repeating object in an image. While the method relies on a fairly sophisticated deformable part model, unlike existing techniques it estimates the model parameters in an…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Inbar Huberman , Raanan Fattal

We propose a new measure of support (the number of occur- rences of a pattern), in which instances are more important if they occur with a certain frequency and close after each other in the stream of trans- actions. We will explain this…

Artificial Intelligence · Computer Science 2007-05-23 Edgar de Graaf , Jeannette de Graaf , Walter A. Kosters

Fabric image retrieval is beneficial to many applications including clothing searching, online shopping and cloth modeling. Learning pairwise image similarity is of great importance to an image retrieval task. With the resurgence of…

Computer Vision and Pattern Recognition · Computer Science 2018-01-01 Daiguo Deng , Ruomei Wang , Hefeng Wu , Huayong He , Qi Li , Xiaonan Luo

Motivation: Illumina DNA sequencing is now the predominant source of raw genomic data, and data volumes are growing rapidly. Bioinformatic analysis pipelines are having trouble keeping pace. A common bottleneck in such pipelines is the…

Genomics · Quantitative Biology 2014-09-09 Gregory G. Faust , Ira M. Hall

Clustering is a difficult and widely-studied data mining task, with many varieties of clustering algorithms proposed in the literature. Nearly all algorithms use a similarity measure such as a distance metric (e.g. Euclidean distance) to…

Neural and Evolutionary Computing · Computer Science 2019-10-24 Andrew Lensen , Bing Xue , Mengjie Zhang
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