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Clustering is widely used in unsupervised learning to find homogeneous groups of observations within a dataset. However, clustering mixed-type data remains a challenge, as few existing approaches are suited for this task. This study…

Machine Learning · Statistics 2025-11-26 Badih Ghattas , Alvaro Sanchez San-Benito

Cluster-level dynamic treatment regimens can be used to guide sequential, intervention or treatment decision-making at the cluster level in order to improve outcomes at the individual or patient-level. In a cluster-level DTR, the…

Methodology · Statistics 2016-07-15 Timothy NeCamp , Amy Kilbourne , Daniel Almirall

A novel non-parametric estimator of the correlation between grouped measurements of a quantity is proposed in the presence of noise. This work is primarily motivated by functional brain network construction from fMRI data, where brain…

Methodology · Statistics 2023-02-16 Hanâ Lbath , Alexander Petersen , Wendy Meiring , Sophie Achard

Functional neuroimaging can measure the brain?s response to an external stimulus. It is used to perform brain mapping: identifying from these observations the brain regions involved. This problem can be cast into a linear supervised…

Machine Learning · Computer Science 2012-07-03 Gael Varoquaux , Alexandre Gramfort , Bertrand Thirion

This article explores and analyzes the unsupervised clustering of large partially observed graphs. We propose a scalable and provable randomized framework for clustering graphs generated from the stochastic block model. The clustering is…

Social and Information Networks · Computer Science 2022-12-06 Mostafa Rahmani , Andre Beckus , Adel Karimian , George Atia

Understanding the structure of the brain, and how it changes with time and disease, is a core goal of structural neuroimaging. Contemporary approaches to structural brain analysis are dominated by voxel-wise, mass-univariate methods such as…

Algebraic Topology · Mathematics 2026-04-28 Donato Quiccione , Mariam Pirashvili , Nathan Broomhead , Sean J. Fallon

Statistical analysis of multimodal imaging data is a challenging task, since the data involves high-dimensionality, strong spatial correlations and complex data structures. In this paper, we propose rigorous statistical testing procedures…

Methodology · Statistics 2023-03-08 Jinyuan Chang , Jing He , Jian Kang , Mingcong Wu

Cluster analysis is an unsupervised learning strategy that can be employed to identify subgroups of observations in data sets of unknown structure. This strategy is particularly useful for analyzing high-dimensional data such as microarray…

Methodology · Statistics 2016-10-07 Erika S. Helgeson , Eric Bair

Alterations in brain connectivity have been associated with a variety of clinical disorders using functional magnetic resonance imaging (fMRI). We investigated empirically how the number of brain parcels (or scale) impacted the results of a…

Quantitative Methods · Quantitative Biology 2015-01-28 P. Bellec , Y. Benhajali , F. Carbonell , C. Dansereau , G. Albouy , M. Pelland , C. Craddock , O. Collignon , J. Doyon , E. Stip , P. Orban

Unsupervised machine learning, and in particular data clustering, is a powerful approach for the analysis of datasets and identification of characteristic features occurring throughout a dataset. It is gaining popularity across scientific…

Mesoscale and Nanoscale Physics · Physics 2021-03-23 Maria El Abbassi , Jan Overbeck , Oliver Braun , Michel Calame , Herre S. J. van der Zant , Mickael L. Perrin

This paper presents a new approach to non-parametric cluster analysis called Adaptive Weights Clustering (AWC). The idea is to identify the clustering structure by checking at different points and for different scales on departure from…

Machine Learning · Statistics 2017-09-27 Kirill Efimov , Larisa Adamyan , Vladimir Spokoiny

We formulate a novel technique for the detection of functional clusters in discrete event data. The advantage of this algorithm is that no prior knowledge of the number of functional groups is needed, as our procedure progressively combines…

Neurons and Cognition · Quantitative Biology 2015-05-13 S. Feldt , J. Waddell , V. L. Hetrick , J. D. Berke , M. Zochowski

Diffusion Magnetic Resonance Imaging (MRI) exploits the anisotropic diffusion of water molecules in the brain to enable the estimation of the brain's anatomical fiber tracts at a relatively high resolution. In particular, tractographic…

Computational Engineering, Finance, and Science · Computer Science 2016-09-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

Cluster number is typically a parameter selected at the outset in clustering problems, and while impactful, the choice can often be difficult to justify. Inspired by bioinformatics, this study examines how the nature of clusters varies with…

Machine Learning · Computer Science 2025-02-25 Justin Miller , Tristram Alexander

The clustering coefficient quantifies the abundance of connected triangles in a network and is a major descriptive statistics of networks. For example, it finds an application in the assessment of small-worldness of brain networks, which is…

Physics and Society · Physics 2018-06-28 Naoki Masuda , Michiko Sakaki , Takahiro Ezaki , Takamitsu Watanabe

Normative models of brain structure estimate the effects of covariates such as age and sex using large samples of healthy controls. These models can then be applied to e.g. smaller clinical cohorts to distinguish disease effects from other…

Resting-state fMRI has become a valuable tool for classifying brain disorders and constructing brain functional connectivity networks by tracking BOLD signals across brain regions. However, existing mod els largely neglect the…

Machine Learning · Computer Science 2025-11-18 Yue Xun , Jiaxing Xu , Wenbo Gao , Chen Yang , Shujun Wang

Automatic tissue segmentation of fetal brain images is essential for the quantitative analysis of prenatal neurodevelopment. However, producing voxel-level annotations of fetal brain imaging is time-consuming and expensive. To reduce…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Zihang Xu , Haifan Gong , Xiang Wan , Haofeng Li

Data clustering involves identifying latent similarities within a dataset and organizing them into clusters or groups. The outcomes of various clustering algorithms differ as they are susceptible to the intrinsic characteristics of the…

Machine Learning · Computer Science 2024-07-31 Bryar A. Hassan , Noor Bahjat Tayfor , Alla A. Hassan , Aram M. Ahmed , Tarik A. Rashid , Naz N. Abdalla

Clustering algorithms are one of the main analytical methods to detect patterns in unlabeled data. Existing clustering methods typically treat samples in a dataset as points in a metric space and compute distances to group together similar…

Machine Learning · Computer Science 2021-10-12 Tarek Naous , Srinjay Sarkar , Abubakar Abid , James Zou
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