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In the 70s a novel branch of statistics emerged focusing its effort in selecting a function in the pattern recognition problem, which fulfils a definite relationship between the quality of the approximation and its complexity. These…

Machine Learning · Statistics 2022-02-10 J M Gorriz , SiPBA Group , CAM neuroscience

We consider the problem of model-based clustering in the presence of many correlated, mixed continuous and discrete variables, some of which may have missing values. Discrete variables are treated with a latent continuous variable approach…

Functional magnetic resonance imaging (fMRI) is a crucial technology for gaining insights into cognitive processes in humans. Data amassed from fMRI measurements result in volumetric data sets that vary over time. However, analysing such…

Neurons and Cognition · Quantitative Biology 2020-10-23 Bastian Rieck , Tristan Yates , Christian Bock , Karsten Borgwardt , Guy Wolf , Nicholas Turk-Browne , Smita Krishnaswamy

Advances in large-scale neural recordings have expanded our ability to describe the activity of distributed brain circuits. However, understanding how neural population dynamics differ across regions and behavioral contexts remains…

In this paper, we focus on how to locate the relevant or discriminative brain regions related with external stimulus or certain mental decease, which is also called support identification, based on the neuroimaging data. The main difficulty…

Computer Vision and Pattern Recognition · Computer Science 2015-06-09 Yilun Wang , Sheng Zhang , Junjie Zheng , Heng Chen , Huafu Chen

Multivoxel pattern analysis (MVPA) has gained enormous popularity in the neuroimaging community over the past few years. At the group level, most MVPA studies adopt an "information based" approach in which the sign of the effect of…

Quantitative Methods · Quantitative Biology 2016-09-07 Roee Gilron , Jonathan Rosenblatt , Oluwasanmi Koyejo , Russell A. Poldrack , Roy Mukamel

Genetic data are frequently categorical and have complex dependence structures that are not always well understood. For this reason, clustering and classification based on genetic data, while highly relevant, are challenging statistical…

Methodology · Statistics 2016-06-13 Gabriela Bettella Cybis , Marcio Valk , Silvia Regina Costa Lopes

With advances in neural recording techniques, neuroscientists are now able to record the spiking activity of many hundreds of neurons simultaneously, and new statistical methods are needed to understand the structure of this large-scale…

Neurons and Cognition · Quantitative Biology 2023-03-03 Ganchao Wei , Ian H. Stevenson , Xiaojing Wang

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

Biological and social systems consist of myriad interacting units. The interactions can be represented in the form of a graph or network. Measurements of these graphs can reveal the underlying structure of these interactions, which provides…

Machine Learning · Statistics 2017-10-25 Norbert Binkiewicz , Joshua T. Vogelstein , Karl Rohe

The use of brain images as markers for diseases or behavioral differences is challenged by the small effects size and the ensuing lack of power, an issue that has incited researchers to rely more systematically on large cohorts. Coupled…

Machine Learning · Statistics 2015-11-17 Bertrand Thirion , Andrés Hoyos-Idrobo , Jonas Kahn , Gael Varoquaux

Anomaly detection and localization in images is a growing field in computer vision. In this area, a seemingly understudied problem is anomaly clustering, i.e., identifying and grouping different types of anomalies in a fully unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Andrei-Timotei Ardelean , Tim Weyrich

Cluster inference based on spatial extent thresholding is the most popular analysis method for finding activated brain areas in neuroimaging. However, the method has several well-known issues. While powerful for finding brain regions with…

Methodology · Statistics 2022-08-10 Jelle J. Goeman , Paweł\ Górecki , Ramin Monajemi , Xu Chen , Thomas E. Nichols , Wouter Weeda

Brain atlases are a ubiquitous tool used for analyzing and interpreting brain imaging datasets. Traditionally, brain atlases divided the brain into regions separated by anatomical landmarks. In the last decade, several attempts have been…

Quantitative Methods · Quantitative Biology 2018-02-08 Pantea Moghimi , Kelvin O. Lim , Theoden I. Netoff

We propose a change-point detection method for large scale multiple testing problems with data having clustered signals. Unlike the classic change-point setup, the signals can vary in size within a cluster. The clustering structure on the…

Methodology · Statistics 2021-10-07 Hongyuan Cao , Wei Biao Wu

A main task in data analysis is to organize data points into coherent groups or clusters. The stochastic block model is a probabilistic model for the cluster structure. This model prescribes different probabilities for the presence of edges…

Machine Learning · Computer Science 2020-09-24 Alexander Jung

In this paper, we analyze electroencephalograms (EEG) which are recordings of brain electrical activity. We develop new clustering methods for identifying synchronized brain regions, where the EEGs show similar oscillations or waveforms…

Methodology · Statistics 2020-07-29 Tianbo Chen , Ying Sun , Carolina Euan , Hernando Ombao

Deep neural two-sample tests have recently shown strong power for detecting distributional differences between groups, yet their black-box nature limits interpretability and practical adoption in biomedical analysis. Moreover, most existing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Masoumeh Javanbakhat , Piotr Komorowski , Dilyara Bareeva , Wei-Chang Lai , Wojciech Samek , Christoph Lippert

Clustering is one of the most universal approaches for understanding complex data. A pivotal aspect of clustering analysis is quantitatively comparing clusterings; clustering comparison is the basis for many tasks such as clustering…

Machine Learning · Statistics 2019-06-13 Alexander J. Gates , Ian B. Wood , William P. Hetrick , Yong-Yeol Ahn

In many modern statistical problems, the limited available data must be used both to develop the hypotheses to test, and to test these hypotheses-that is, both for exploratory and confirmatory data analysis. Reusing the same dataset for…

Methodology · Statistics 2023-07-24 Youngjoo Yun , Rina Foygel Barber