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An applied problem facing all areas of data science is harmonizing data sources. Joining data from multiple origins with unmapped and only partially overlapping features is a prerequisite to developing and testing robust, generalizable…

Template matching is a fundamental problem in computer vision with applications in fields including object detection, image registration, and object tracking. Current methods rely on nearest-neighbour (NN) matching, where the query feature…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Ankit Gupta , Ida-Maria Sintorn

3D fluorescence microscopy of living organisms has increasingly become an essential and powerful tool in biomedical research and diagnosis. An exploding amount of imaging data has been collected, whereas efficient and effective…

Image and Video Processing · Electrical Eng. & Systems 2019-11-28 Yang Jiao , Mo Weng , Mei Yang

Ptychography is an enabling coherent diffraction imaging technique for both fundamental and applied sciences. Its applications in optical microscopy, however, fall short for its low imaging throughput and limited resolution. Here, we report…

The Lamb shift of a quantum emitter very close to a plasmonic nanostructure, mainly induced by the higher-order plasmonic dark modes, can be three or more orders of magnitude larger than that in the free space and it is ultra-sensitive to…

Quantum Physics · Physics 2023-06-06 Zeyang Liao , Yuwei Lu , Xue-Hua Wang

Network alignment (NA) aims to find a node mapping between molecular networks of different species that identifies topologically or functionally similar network regions. Analogous to genomic sequence alignment, NA can be used to transfer…

Molecular Networks · Quantitative Biology 2016-04-07 Vipin Vijayan , Tijana Milenkovic

Motivation: Recent advances in sequencing technologies promise ultra-long reads of $\sim$100 kilo bases (kb) in average, full-length mRNA or cDNA reads in high throughput and genomic contigs over 100 mega bases (Mb) in length. Existing…

Genomics · Quantitative Biology 2018-09-17 Heng Li

Accurate grain orientation mapping is essential for understanding and optimizing the performance of polycrystalline materials, particularly in energy-related applications. Lithium nickel oxide (LiNiO$_{2}$) is a promising cathode material…

Disordered Systems and Neural Networks · Physics 2025-11-26 Sebastian Wissel , Jonas Scheunert , Aaron Dextre , Shamail Ahmed , Andreas Bayer , Kerstin Volz , Bai-Xiang Xu

Conventional nano-photonic schemes minimise multiple scattering to realise a miniaturised version of beam-splitters, interferometers and optical cavities for light propagation and lasing. Here instead, we introduce a nanophotonic network…

Karyotyping is a process in which chromosomes in a dividing cell are properly stained, identified and displayed in a standard format, which helps geneticist to study and diagnose genetic factors behind various genetic diseases and for…

Computer Vision and Pattern Recognition · Computer Science 2012-05-10 K. S. Sreejini , A. Lijiya , V. K. Govindan

The light scattering of multilayer nanoparticles can be solved by Maxwell equations. However, it is difficult to solve the inverse design of multilayer nanoparticles by using the traditional trial-and-error method. Here, we present a method…

Signal Processing · Electrical Eng. & Systems 2020-03-19 Cankun Qiu , Zhi Luo , Xia Wu , Huidong Yang , Bo Huang

Sliding is one of the fundamental mechanical movements in machinery. In macroscopic systems, double-rack pinion machines employ gears to slide two linear tracks along opposite directions. In microscopic systems, kinesin-5 proteins crosslink…

Biological Physics · Physics 2021-05-04 Maximilian J. Urban , Steffen Both , Chao Zhou , Anton Kuzyk , Klas Lindfors , Thomas Weiss , Na Liu

In the rapidly evolving field of optical engineering, precise alignment of multi-lens imaging systems is critical yet challenging, as even minor misalignments can significantly degrade performance. Traditional alignment methods rely on…

Optics · Physics 2025-07-01 Tomer Slor , Dean Oren , Shira Baneth , Tom Coen , Haim Suchowski

We performed a visualization of membrane proteins labeled with 10-nm gold nanoparticles in cells, using an all-optical method based on photothermal interference contrast. The high sensitivity of the method and the stability of the signals…

The increasing size of screening libraries poses a significant challenge for the development of virtual screening methods for drug discovery, necessitating a re-evaluation of traditional approaches in the era of big data. Although 3D…

Machine Learning · Computer Science 2025-03-17 Daniel Rose , Oliver Wieder , Thomas Seidel , Thierry Langer

Although fluorescence is the prevailing labeling technique in biosensing applications, sensitivity improvement is still a striving challenge. We show that coating standard microscope slides with nanoroughened silver films provides a high…

Instrumentation and Detectors · Physics 2013-07-29 Eric Le Moal , Sandrine Lévêque-Fort , Marie-Claude Pottier , Emmanuel Fort

Deterministic placement and dynamic manipulation of individual plasmonic nanoparticles with nanoscale precision feature an important step towards active nanoplasmonic devices with prescribed levels of performance and functionalities at…

Biological Physics · Physics 2018-03-20 Maximilian J. Urban , Chao Zhou , Xiaoyang Duan , Na Liu

Metallic nanohole arrays have shown their potential as sensing tools. Important research supported by sophisticated laboratory experiments have been recently carried out, that may help to develop practical devices to be implemented in the…

Applied Physics · Physics 2019-05-01 A. Franco , D. Otaduy , A. I. Barreda , J. L. FernÁndez-Luna , S. Merino , F. GonzÁlez , F. Moreno

In order to relate nanoparticle properties to function, fast and detailed particle characterization, is needed. The ability to characterize nanoparticle samples using optical microscopy techniques has drastically improved over the past few…

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders