Nanoroughened plasmonic films for enhanced biosensing detection
Instrumentation and Detectors
2013-07-29 v1 Biological Physics
Optics
Abstract
Although fluorescence is the prevailing labeling technique in biosensing applications, sensitivity improvement is still a striving challenge. We show that coating standard microscope slides with nanoroughened silver films provides a high fluorescence signal enhancement due to plasmonic interactions. As a proof of concept, we applied these films with tailored plasmonic properties to DNA microarrays. Using common optical scanning devices, we achieved signal amplifications by more than 40-fold.
Cite
@article{arxiv.1307.6981,
title = {Nanoroughened plasmonic films for enhanced biosensing detection},
author = {Eric Le Moal and Sandrine Lévêque-Fort and Marie-Claude Pottier and Emmanuel Fort},
journal= {arXiv preprint arXiv:1307.6981},
year = {2013}
}