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The corticospinal tract (CST) is a critically important white matter fiber tract in the human brain that enables control of voluntary movements of the body. Diffusion MRI tractography is the only method that enables the study of the anatomy…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Jianzhong He , Fan Zhang , Yiang Pan , Yuanjing Feng , Jarrett Rushmore , Erickson Torio , Yogesh Rathi , Nikos Makris , Ron Kikinis , Alexandra J. Golby , Lauren J. O'Donnell

Recent developments in network neuroscience have highlighted the importance of developing techniques for analyzing and modeling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative…

Neurons and Cognition · Quantitative Biology 2022-09-09 Viplove Arora , Enrico Amico , Joaquín Goñi , Mario Ventresca

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

This paper introduces a novel methodology to integrate human brain connectomics and parcellation for brain tumor segmentation and survival prediction. For segmentation, we utilize an existing brain parcellation atlas in the MNI152 1mm space…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Po-Yu Kao , Thuyen Ngo , Angela Zhang , Jefferson W. Chen , B. S. Manjunath

This study introduces a new method of visualizing complex tree structured objects. The usefulness of this method is illustrated in the context of detecting unexpected features in a data set of very large trees. The major contribution is a…

Applications · Statistics 2012-02-14 Burcu Aydin , Gabor Pataki , Haonan Wang , Alim Ladha , Elizabeth Bullitt , J. S. Marron

The comprehensive characterization of the structure of complex networks is essential to understand the dynamical processes which guide their evolution. The discovery of the scale-free distribution and the small world property of real…

Computational Physics · Physics 2009-11-13 Paulino R. Villas Boas , Francisco A. Rodrigues , Gonzalo Travieso , Luciano da F. Costa

Diffusion-weighted magnetic resonance imaging allows for reconstruction of models for structural connectivity in the brain, such as fiber orientation distribution functions (ODFs) that describe the distribution, direction, and volume of…

Effective information analysis generally boils down to properly identifying the structure or geometry of the data, which is often represented by a graph. In some applications, this structure may be partly determined by design constraints or…

Machine Learning · Computer Science 2016-11-07 Dorina Thanou , Xiaowen Dong , Daniel Kressner , Pascal Frossard

In the last decade, network science has shed new light both on the structural (anatomical) and on the functional (correlations in the activity) connectivity among the different areas of the human brain. The analysis of brain networks has…

Physics and Society · Physics 2017-04-18 Federico Battiston , Vincenzo Nicosia , Mario Chavez , Vito Latora

Various modifications of decision trees have been extensively used during the past years due to their high efficiency and interpretability. Tree node splitting based on relevant feature selection is a key step of decision tree learning, at…

Machine Learning · Computer Science 2017-09-05 Dmitry Ignatov , Andrey Ignatov

Pancreas segmentation in medical image processing is a persistent challenge due to its small size, low contrast against adjacent tissues, and significant topological variations. Traditional level set methods drive boundary evolution using…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Yue Gou , Fanghui Song , Yuming Xing , Shengzhu Shi , Zhichang Guo , Boying Wu

The root is an important organ of a plant since it is responsible for water and nutrient uptake. Analyzing and modelling variabilities in the geometry and topology of roots can help in assessing the plant's health, understanding its growth…

Graphics · Computer Science 2021-01-26 Guan Wang , Hamid Laga , Jinyuan Jia , Stanley J. Miklavcic , Anuj Srivastava

Diffusion tractography in brain connectomics often involves tracing axonal trajectories across gray-white matter boundaries in gyral blades of complex cortical convolutions. To date, gyral bias is observed in most tractography algorithms…

Neurons and Cognition · Quantitative Biology 2019-04-15 Ye Wu , Yoonmi Hong , Yuanjing Feng , Dinggang Shen , Pew-Thian Yap

Identification of white matter fiber tracts of the brain is crucial for delineating the tumor border during neurosurgery. A custom-built Mueller polarimeter was used in reflection configuration for the wide-field imaging of thick section of…

While normalizing flows for continuous data have been extensively researched, flows for discrete data have only recently been explored. These prior models, however, suffer from limitations that are distinct from those of continuous flows.…

Machine Learning · Computer Science 2022-07-06 Mai Elkady , Jim Lim , David I. Inouye

Diffusion MRI tractography enables in vivo reconstruction of white matter (WM) pathways. Two key tasks in tractography analysis include: 1) tractogram registration that aligns streamlines across individuals, and 2) streamline clustering…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Yijie Li , Xi Zhu , Junyi Wang , Ye Wu , Lauren J. O'Donnell , Fan Zhang

Spatial functional organization is a hallmark of biological brains: neurons are arranged topographically according to their response properties, at multiple scales. In contrast, representations within most machine learning models lack…

Computation and Language · Computer Science 2025-10-22 Taha Binhuraib , Greta Tuckute , Nicholas Blauch

Natural and man-made transport webs are frequently dominated by dense sets of nested cycles. The architecture of these networks, as defined by the topology and edge weights, determines how efficiently the networks perform their function.…

Quantitative Methods · Quantitative Biology 2016-07-27 Carl D. Modes , Marcelo O. Magnasco , Eleni Katifori

In this paper, we propose a novel deep learning architecture combining stacked Bi-directional LSTM and LSTMs with the Siamese network architecture for segmentation of brain fibers, obtained from tractography data, into anatomically…

Computer Vision and Pattern Recognition · Computer Science 2017-12-29 Shreyas Malakarjun Patil , Aditya Nigam , Arnav Bhavsar , Chiranjoy Chattopadhyay

Diffusion Tensor Imaging (DTI) provides the possibility of estimating the location and course of eloquent structures in the human brain. Knowledge about this is of high importance for preoperative planning of neurosurgical interventions and…

Computer Vision and Pattern Recognition · Computer Science 2011-03-11 Miriam H. A. Bauer , Jan Egger , Daniela Kuhnt , Sebastiano Barbieri , Jan Klein , Horst K. Hahn , Bernd Freisleben , Christopher Nimsky