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We present a hybrid method that performs the complete parcellation of the cerebral cortex of an individual, based on the connectivity information of the white matter fibers from a whole-brain tractography dataset. The method consists of…

Neurons and Cognition · Quantitative Biology 2020-02-24 Narciso López-López , Andrea Vázquez , Cyril Poupon , Jean-François Mangin , Pamela Guevara

Airborne laser scanning (LiDAR) point clouds over large forested areas can be processed to segment individual trees and subsequently extract tree-level information. Existing segmentation procedures typically detect more than 90% of…

Computer Vision and Pattern Recognition · Computer Science 2017-08-04 Hamid Hamraz , Marco A. Contreras , Jun Zhang

Diffusion magnetic resonance imaging (dMRI) and tractography provide means to study the anatomical structures within the white matter of the brain. When studying tractography data across subjects, it is usually necessary to align, i.e. to…

Machine Learning · Statistics 2016-02-01 Thien Bao Nguyen , Emanuele Olivetti , Paolo Avesani

Traumatic brain injury (TBI) disrupts thalamocortical connectivity, contributing to cognitive impairment and post-traumatic epilepsy (PTE). This study presents a novel tractography-based framework that leverages diffusion maps to capture…

Quantitative Methods · Quantitative Biology 2025-10-21 Akul Sharma , Anand A. Joshi , Richard M. Leahy

Disease in the brain is often associated with subtle, spatially diffuse, or complex tissue changes that may lie beneath the level of gross visual inspection, even on magnetic resonance imaging (MRI). Unfortunately, current computer-assisted…

Computer Vision and Pattern Recognition · Computer Science 2017-05-16 Shinjini Kundu , Soheil Kolouri , Kirk I Erickson , Arthur F Kramer , Edward McAuley , Gustavo K Rohde

Parcellation of human cerebellar pathways is essential for advancing our understanding of the human brain. Existing diffusion MRI tractography parcellation methods have been successful in defining major cerebellar fibre tracts, while…

We study diffusion of information packets on several classes of structured networks. Packets diffuse from a randomly chosen node to a specified destination in the network. As local transport rules we consider random diffusion and an…

Statistical Mechanics · Physics 2015-06-24 Bosiljka Tadic , Stefan Thurner

Tractography is typically performed for each subject using the diffusion tensor imaging (DTI) data in its native subject space rather than in some space common to the entire study cohort. Despite performing tractography on a population…

Visual representations can be defined as the activations of neuronal populations in response to images. The activation of a neuron as a function over all image space has been described as a "tuning landscape". As a function over a…

Neurons and Cognition · Quantitative Biology 2022-12-29 Binxu Wang , Carlos R. Ponce

The leaves of angiosperms contain highly complex venation networks consisting of recursively nested, hierarchically organized loops. We describe a new phenotypic trait of reticulate vascular networks based on the topology of the nested…

Quantitative Methods · Quantitative Biology 2016-06-23 Henrik Ronellenfitsch , Jana Lasser , Douglas C. Daly , Eleni Katifori

Cranial nerves (CNs) play a crucial role in various essential functions of the human brain, and mapping their pathways from diffusion MRI (dMRI) provides valuable preoperative insights into the spatial relationships between individual CNs…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Lei Xie , Jiahao Huang , Jiawei Zhang , Jianzhong He , Yiang Pan , Guoqiang Xie , Mengjun Li , Qingrun Zeng , Mingchu Li , Yuanjing Feng

Contour trees describe the topology of level sets in scalar fields and are widely used in topological data analysis and visualization. A main challenge of utilizing contour trees for large-scale scientific data is their computation at scale…

Computational Geometry · Computer Science 2024-10-01 Mingzhe Li , Hamish Carr , Oliver Rübel , Bei Wang , Gunther H. Weber

Diffusion MRI (dMRI) tractography is currently the only method for in vivo mapping of the brain's white matter (WM) connections. Tractometry is an advanced tractography analysis technique for along-tract profiling to investigate the…

Quantitative Methods · Quantitative Biology 2026-01-29 Ruixi Zheng , Wei Zhang , Yijie Li , Xi Zhu , Zhou Lan , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Lauren J. O'Donnell , Fan Zhang

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

White matter fiber clustering (WMFC) enables parcellation of white matter tractography for applications such as disease classification and anatomical tract segmentation. However, the lack of ground truth and the ambiguity of fiber data (the…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Yuqian Chen , Chaoyi Zhang , Yang Song , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

In this paper, we present a flexible and probabilistic framework for tracking topological features in time-varying scalar fields using merge trees and partial optimal transport. Merge trees are topological descriptors that record the…

Computational Geometry · Computer Science 2025-08-26 Mingzhe Li , Xinyuan Yan , Lin Yan , Tom Needham , Bei Wang

Given a 3D surface defined by an elevation function on a 2D grid as well as non-spatial features observed at each pixel, the problem of surface segmentation aims to classify pixels into contiguous classes based on both non-spatial features…

Computer Vision and Pattern Recognition · Computer Science 2020-08-27 Wenchong He , Arpan Man Sainju , Zhe Jiang , Da Yan

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial strategy for white matter (WM) parcellation. Current methods primarily use the geometric information of fibers (i.e., the spatial trajectories) to group similar fibers…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Jin Wang , Bocheng Guo , Yijie Li , Junyi Wang , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang

Functional brain graphs are often characterized with separate graph-theoretic or spectral descriptors, overlooking how these properties covary and partially overlap across brains and conditions. We anticipate that dense, weighted functional…

Neurons and Cognition · Quantitative Biology 2025-11-07 Subati Abulikemu , Tiago Azevedo , Michail Mamalakis , John Suckling

Materials like paper, consisting of a network of natural fibres, exposed to variations in moisture, undergo changes in geometrical and mechanical properties. This behaviour is particularly important for understanding the hygro-mechanical…

Computational Engineering, Finance, and Science · Computer Science 2020-06-26 P. Samantray , R. H. J. Peerlings , E. Bosco , M. G. D. Geers , T. J. Massart , O. Rokoš
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