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Buckling instabilities driven by tissue growth underpin key developmental events such as the folding of the brain. Tissue growth is disordered due to cell-to-cell variability, but the effects of this variability on buckling are unknown.…

Soft Condensed Matter · Physics 2025-12-12 Rahul G. Ramachandran , Ricard Alert , Pierre A. Haas

During animal development and homeostasis, the structure of tissues, including muscles, blood vessels and connective tissues adapts to mechanical strains in the extracellular matrix (ECM). These strains originate from the differential…

Cell Behavior · Quantitative Biology 2017-03-06 Elisabeth G. Rens , Roeland M. H. Merks

In extra-dimensional scenarios oscillations between active and sterile neutrinos can be governed by a new resonance in the oscillation amplitude. This resonance results when cancelation occurs between two phase differences, the usual…

High Energy Physics - Phenomenology · Physics 2015-05-13 Sebastian Hollenberg , Octavian Micu , Heinrich Päs , Thomas J. Weiler

Plant organ outgrowth superficially appears like the continuous mechanical deformation of a sheet of cells. Yet, how precisely cells as individual mechanical entities can act to morph a tissue reliably and efficiently into three dimensions…

Biological Physics · Physics 2020-04-28 Jason Khadka , Jean-Daniel Julien , Karen Alim

Noise in the expression of a gene produces fluctuations in the concentration of the gene product. These fluctuations can interfere with optimal function or can be exploited to generate beneficial diversity between cells; gene expression…

Molecular Networks · Quantitative Biology 2015-05-13 Namiko Mitarai , Ian B. Dodd , Michael T. Crooks , Kim Sneppen

A model of the columnar functional organization of neocortical association areas is studied. The neuronal network is composed of many Hebbian autoassociators, or modules, each of which interacts with a relatively small number of the others.…

Disordered Systems and Neural Networks · Physics 2020-05-14 Carlo Fulvi Mari

Microtubules (MTs) are dynamic protein filaments essential for intracellular organization and transport, particularly in long-lived cells such as neurons. The plus and minus ends of neuronal MTs switch between growth and shrinking phases,…

Biological Physics · Physics 2025-07-11 Anna C. Nelson , Scott A. McKinley , Melissa M. Rolls , Maria-Veronica Ciocanel

Neuronal growth cones are the most sensitive amongst eukaryotic cells in responding to directional chemical cues. Although a dynamic microtubule cytoskeleton has been shown to be essential for growth cone turning, the precise nature of…

Subcellular Processes · Quantitative Biology 2019-05-16 Saurabh Mahajan , Chaitanya A. Athale

Lateral inhibition resulting from a double-negative feedback loop underlies the assignment of different fates to cells in many developmental processes. Previous studies have shown that the presence of time delays in models of lateral…

Cell Behavior · Quantitative Biology 2015-05-13 Hiroshi Momiji , Nicholas A. M. Monk

The quintessential property of neuronal systems is their intensive patterns of selective synaptic connections. The current work describes a physics-based approach to neuronal shape modeling and synthesis and its consideration for the…

Neurons and Cognition · Quantitative Biology 2009-11-10 Luciano da Fontoura Costa , Regina Celia Coelho

Oscillations of neutrinos $\nu_L \leftrightarrow \nu_R$ in presence of an arbitrary electromagnetic field are considered. We introduce the Hamiltonian for the neutrino spin evolution equation that accounts for possible effects of…

High Energy Physics - Phenomenology · Physics 2009-10-31 A. M. Egorov , A. E. Lobanov , A. I. Studenikin

Cells and tissues exhibit oscillatory deformations during remodelling, migration or embryogenesis. Although it has been shown that these oscillations correlate with cell biochemical signalling, it is yet unclear the role of these…

Tissues and Organs · Quantitative Biology 2021-01-20 Malik A Dawi , Jose J Munoz

We consider the effect of distributed delays in neural feedback systems. The avian optic tectum is reciprocally connected with the nucleus isthmi. Extracellular stimulation combined with intracellular recordings reveal a range of signal…

Biological Physics · Physics 2007-12-04 Ulrike Meyer , Jing Shao , Saurish Chakrabarty , Sebastian F. Brandt , Harald Luksch , Ralf Wessel

We demonstrate that the coupling of excitonic and vibrational motion in biological complexes can provide mechanisms to explain the long-lived oscillations that have been obtained in non linear spectroscopic signals of different…

Chemical Physics · Physics 2015-06-17 M. B. Plenio , J. Almeida , S. F. Huelga

Neural oscillations are universal phenomena and can be observed at different levels of neural systems, from single neuron to macroscopic brain. The frequency of those oscillations are related to the brain functions. However, little is know…

Neurons and Cognition · Quantitative Biology 2015-07-30 Lianchun Yu , Longfei Wang , Fei Jia , Duojie Jia

Inflammatory responses in eucaryotic cells are often associated with oscillations in the nuclear-cytoplasmic translocation of the transcription factor NF-kB. In most laboratory realizations, the oscillations are triggered by a cytokine…

Biological Physics · Physics 2011-12-30 Mogens H. Jensen , Sandeep Krishna

We explore the joint effect of the intrinsic noise and time delay on the spatial pattern formation within a multi-scale mobile lattice model of the epithelium. The protein fluctuations are driven by transcription/translation processes in…

Adaptation and Self-Organizing Systems · Physics 2015-06-12 Dmitry Bratsun , Andrey Zakharov

The paper highlights the role of a positive feedback gating mechanism at the cellular level in the robust- ness and modulation properties of rhythmic activities at the circuit level. The results are presented in the context of half-center…

Neurons and Cognition · Quantitative Biology 2014-12-22 Julie Dethier , Guillaume Drion , Alessio Franci , Rodolphe Sepulchre

The cell nucleus is enveloped by a complex membrane, whose wrinkling has been implicated in disease and cellular aging. The biophysical dynamics and spectral evolution of nuclear wrinkling during multicellular development remain poorly…

Contractile forces exerted on the surrounding extracellular matrix (ECM) lead to the alignment and stretching of constituent fibers within the vicinity of cells. As a consequence, the matrix reorganizes to form thick bundles of aligned…

Cell Behavior · Quantitative Biology 2014-09-23 Abhilash Nair , Brendon M. Baker , Britta Trappmann , Christopher S. Chen , Vivek B. Shenoy