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Many of the processes that underly neural computation are carried out by ion channels embedded in the plasma membrane, a two-dimensional liquid that surrounds all cells. Recent experiments have demonstrated that this membrane is poised…

Biological Physics · Physics 2016-07-26 Ofer Kimchi , Sarah L. Veatch , Benjamin B. Machta

It is not merely the position of residues that are of utmost importance in protein function and stability, but the interactions between them. We illustrate, by using a network construction on a set of 595 non-homologous proteins, that…

Soft Condensed Matter · Physics 2007-05-23 Ali Rana Atilgan , Pelin Akan , Canan Baysal

The work distribution function for a non-relativistic, non-interacting quantum many-body system interacting with classical external sources is investigated. Exact expressions for the characteristic function corresponding to the work…

Quantum Physics · Physics 2020-04-22 Fardin Kheirandish

We describe power-dependent dynamics of conversion of the guided modes of various guiding structures due to nearly resonant longitudinal modulation of the nonlinear coefficient of the medium. It is shown that the control of the energy…

Proteins created by combinatorial methods in vitro are an important source of information for understanding sequence-structure-function relationships. Alignments of folded proteins from combinatorial libraries can be analyzed using methods…

Biomolecules · Quantitative Biology 2007-05-23 Jeffrey B. Endelman , Jesse D. Bloom , Christopher R. Otey , Marco Landwehr , Frances H. Arnold

We investigate magnetic fluctuations of a mesoscopic critical region at the interface induced by smooth time-independent spacial changes of a control parameter across its critical value. Near the spatial critical point, the order parameter…

Mesoscale and Nanoscale Physics · Physics 2023-09-25 Saikat Banerjee , Nikolai A. Sinitsyn

The theoretical framework for higher-order correlation functions involving multiple times and multiple points in a classical, many-body system developed by Van Zon and Schofield [Phys. Rev. E 65, 011106 (2002)] is extended here to include…

Statistical Mechanics · Physics 2007-05-23 Ramses van Zon , Jeremy Schofield

Myosin II is the muscle molecular motor that works in two bipolar arrays in each thick filament of the striated (skeletal and cardiac) muscle, converting the chemical energy into steady force and shortening by cyclic ATP--driven…

We consider the information transmission problem in neurons and its possible implications for learning in neural networks. Our approach is based on recent developments in statistical physics and complexity science. Combining sensory…

Neurons and Cognition · Quantitative Biology 2025-09-30 Siddharth Kackar

Lifetimes of bound states of protein complexes or biomolecule folded states typically decrease when subject to mechanical force. However, a plethora of biological systems exhibit the counter-intuitive phenomenon of catch bonding, where…

Biomolecules · Quantitative Biology 2016-01-12 Shaon Chakrabarti , Michael Hinczewski , D. Thirumalai

The effect of stochasticity, in the form of Gaussian white noise, in a predator-prey model with two distinct time-scales is presented. A supercritical singular Hopf bifurcation yields a Type II excitability in the deterministic model. We…

Dynamical Systems · Mathematics 2017-07-20 Susmita Sadhu

Flavins are the chromophores in several blue-light-sensitive photoreceptor proteins and act as redox cofactors in many enzymes relevant for biological processes. Despite their biological relevance and numerous, detailed optical…

We present a simple model of protein folding dynamics that captures key qualitative elements recently seen in all-atom simulations. The goals of this theory are to serve as a simple formalism for gaining deeper insight into the physical…

Biological Physics · Physics 2015-05-19 Vijay S. Pande

With the help of transport and statistical models, we find that the ratios of higher net-proton cumulants measured at RHIC are dominated by the statistical fluctuations. Future measurements should focus on the dynamical fluctuations, which…

Nuclear Theory · Physics 2011-01-06 Chen Lizhu , Pan Xue , Xiong Fengbo , Li Lin , Li Na , Li Zhiming , Gang Wang , Wu Yuanfang

Biological molecular machines are proteins that operate under isothermal conditions hence are referred to as free energy transducers. They can be formally considered as enzymes that simultaneously catalyze two chemical reactions: the free…

Biological Physics · Physics 2014-02-05 Michal Kurzynski , Mieczyslaw Torchala , Przemyslaw Chelminiak

We develop a theory for fluctuations and correlations in a gas evolving under ballistic annihilation dynamics. Starting from the hierarchy of equations governing the evolution of microscopic densities in phase space, we subsequently…

Statistical Mechanics · Physics 2009-11-13 P. Maynar , M. I. Garcia de Soria , G. Schehr , A. Barrat , E. Trizac

Protein dynamics has been investigated on a wide range of time scales. Nano- and picosecond dynamics have been assigned to local fluctuations, while slower dynamics have been attributed to larger conformational changes. However, it is…

Protein dynamics is a fundamental element to comprehend their biological functions. However, a theoretical picture providing microscopic-detail explanation of its relevant features is still missing. One of the outmost relevant properties…

Soft Condensed Matter · Physics 2023-06-14 Luca Maggi

A new method is introduced for analysis of interactions between time-dependent coupled oscillators, based on the signals they generate. It distinguishes unsynchronized dynamics from noise-induced phase slips, and enables the evolution of…

Data Analysis, Statistics and Probability · Physics 2012-08-09 Tomislav Stankovski , Andrea Duggento , Peter V. E. McClintock , Aneta Stefanovska

We study nonequilibrium steady states of lattice gases with nearest-neighbor interactions that are driven between two reservoirs. Density profiles in these systems exhibit oscillations close to the reservoirs. We demonstrate that an…

Statistical Mechanics · Physics 2015-05-30 Marcel Dierl , Philipp Maass , Mario Einax