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We formulate a Hele-Shaw type free boundary problem for a tumor growing under the combined effects of pressure forces, cell multiplication and active motion, the latter being the novelty of the present paper. This new ingredient is…

Analysis of PDEs · Mathematics 2014-01-14 Benoît Perthame , Fernando Quirós , Min Tang , Nicolas Vauchelet

We consider two classes of nonlinear eigenvalue problems with double-phase energy and lack of compactness. We establish existence and non-existence results and related properties of solutions. Our analysis combines variational methods with…

Analysis of PDEs · Mathematics 2019-06-24 István Faragó , Dušan Repovš

In this paper, we analyze an eigenvalue problem for quasi-linear elliptic operators involving homogeneous Dirichlet boundary conditions in a open smooth bounded domain. We show that the eigenfunctions corresponding to the eigenvalues belong…

Analysis of PDEs · Mathematics 2021-07-29 Emmanuel Wend Benedo Zongo , Bernhard Ruf

This paper provides results for eigencurves associated with self-adjoint linear elliptic boundary value problems. The elliptic problems are treated as a general two-parameter eigenproblem for a triple (a, b, m) of continuous symmetric…

Analysis of PDEs · Mathematics 2017-05-22 M. A. Rivas , Stephen B. Robinson

We present a perturbative treatment of the evolution under their mutual self-gravity of particles displaced off an infinite perfect lattice, both for a static space and for a homogeneously expanding space as in cosmological N-body…

Astrophysics · Physics 2009-11-11 B. Marcos , T. Baertschiger , M. Joyce , A. Gabrielli , F. Sylos Labini

In this article we study a class of generalised linear systems of difference equations with given boundary conditions and assume that the boundary value problem is non-consistent, i.e. it has infinite many or no solutions. We take into…

Dynamical Systems · Mathematics 2016-10-27 Nicholas Apostolopoulos , Fernando Ortega , Grigoris Kalogeropoulos

In this paper, we look at a linear system of ordinary differential equations as derived from the two-dimensional Ginzburg-Landau equation. In two cases, it is known that this system admits bounded solutions coming from the invariance of the…

Analysis of PDEs · Mathematics 2019-09-30 Anne Beaulieu

The problem of the onset and growth of solid tumour in homogeneous tissue is regarded using an approach based on local interaction between the tumoral and the sane tissue cells. The characteristic sizes and growth rates of spherical…

Cell Behavior · Quantitative Biology 2007-05-23 R. G. Khlebopros , V. A. Slepkov , V. G. Sukhovolsky , Y. V. Mironov , V. E. Fedorov , S. P. Gabuda

In this paper, we prove a theorem concerning the existence of three solutions for the following boundary value problem: \begin{equation*} -\mathcal{M}_{\lambda,\Lambda}^+(D^2u)-\Gamma|Du|^2=f(u)~~~\text{in}\ \Omega, u=0~~~\text{on}\…

Analysis of PDEs · Mathematics 2024-05-01 Mohan Mallick , Ram Baran Verma

We study the mathematical properties of a model of cell division structured by two variables, the size and the size increment, in the case of a linear growth rate and a self-similar fragmentation kernel. We first show that one can construct…

Analysis of PDEs · Mathematics 2019-03-13 Pierre Gabriel , Hugo Martin

The work presents a study of the non-linear mathematical model of tumor growth, proposed by Kolev and Zubik-Kowal (2011). The model is described by a system composed of four partial differential equations that represent the evolution of the…

Tissues and Organs · Quantitative Biology 2025-06-02 Jesika Maganin , Neyva Maria Lopes Romeiro , Eliandro Rodrigues Cirilo , Paulo Laerte Natti

Let $A$ be a symmetric operator. By using the method of boundary triplets we parameterize in terms of a Nevanlinna parameter $\tau$ all exit space extensions $\wt A=\wt A^*$ of $A$ with the discrete spectrum $\s(\wt A)$ and characterize the…

Functional Analysis · Mathematics 2020-07-06 Vadim Mogilevskii

In this paper, we establish regularity and uniqueness results for Grad-Mercier type equations that arise in the context of plasma physics. We show that solutions of this problem naturally develop a dead core, which corresponds to the set…

Analysis of PDEs · Mathematics 2025-04-18 Luis Caffarelli , Antonio Farah , Daniel Restrepo

Nonlinear eigenvalue problems with eigenvector nonlinearities (NEPv) are algebraic eigenvalue problems whose matrix depends on the eigenvector. Applications range from computational quantum mechanics to machine learning. Due to its…

Numerical Analysis · Mathematics 2025-10-06 Victor Janssens , Karl Meerbergen , Wim Michiels

In this paper we initiate the investigation of free boundary minimization problems ruled by general singular operators with $A_2$ weights. We show existence and boundedness of minimizers. The key novelty is a sharp $C^{1+\gamma}$ regularity…

Analysis of PDEs · Mathematics 2020-01-08 Jimmy Lamboley , Yannick Sire , Eduardo V. Teixeira

In this paper we consider a free boundary tumor growth model with a time delay in cell proliferation and study how time delay affects the stability and the size of the tumor. The model is a coupled system of an elliptic equation, a…

Analysis of PDEs · Mathematics 2019-08-20 Xinyue Evelyn Zhao , Bei Hu

We examine the analytic extension of solutions of linear, constant-coefficient initial-boundary value problems outside their spatial domain of definition. We use the Unified Transform Method or Method of Fokas, which gives a representation…

Analysis of PDEs · Mathematics 2022-06-22 Matthew Farkas , Jorge Cisneros , Bernard Deconinck

In this article we consider the following boundary value problem \begin{equation*}\label{abs} \left\{ \begin{aligned} F(x,u,Du,D^{2}u)+c(x)u+ p(x)u^{-\alpha}&=0~\text{in}~\Omega\\ u&=0~~\text{on}~~\partial\Omega, \end{aligned} \right.…

Analysis of PDEs · Mathematics 2024-05-08 Mohan Mallick , Ram Baran Verma

In this work, we study a model consisting of a Cahn-Hilliard-type equation for the concentration of tumour cells coupled to a reaction-diffusion type equation for the nutrient density and a Brinkman-type equation for the velocity. We equip…

Analysis of PDEs · Mathematics 2018-11-19 Matthias Ebenbeck , Harald Garcke

The existence of stationary radial solutions to a partial differential equation arising in the theory of epitaxial growth is studied. Our results depend on the size of a parameter that plays the role of the velocity at which mass is…

Classical Analysis and ODEs · Mathematics 2015-06-17 Carlos Escudero , Robert Hakl , Ireneo Peral , Pedro J. Torres
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