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High-resolution fMRI provides a window into the brain's mesoscale organization. Yet, higher spatial resolution increases scan times, to compensate for the low signal and contrast-to-noise ratio. This work introduces a deep learning-based 3D…

Image and Video Processing · Electrical Eng. & Systems 2024-03-20 Hongwei Bran Li , Matthew S. Rosen , Shahin Nasr , Juan Eugenio Iglesias

I propose a superoscillation measurement method for subdiffraction incoherent optical sources, with potential applications in astronomy, remote sensing, fluorescence microscopy, and spectroscopy. The proposal, based on coherent optical…

Quantum Physics · Physics 2022-10-10 Mankei Tsang

Fluorescence imaging is an essential diagnostic tool in many fields, but diffraction-limited optical imaging at depth is limited by scattering. Here, we present a method based on multiple random illuminations, combined with a computational…

Optics · Physics 2026-03-30 Lei Zhu , Tengfei Wu , Bernhard Rauer , Hilton B. de Aguiar , Sylvain Gigan

Modern imaging techniques at the molecular scale rely on utilizing novel coherent light sources like X-ray free electron lasers for the ultimate goal of visualizing such objects as individual biomolecules rather than crystals. Here, unlike…

Miniature fluorescence microscopes are a standard tool in systems biology. However, widefield miniature microscopes capture only 2D information, and modifications that enable 3D capabilities increase the size and weight and have poor…

Image and Video Processing · Electrical Eng. & Systems 2020-10-13 Kyrollos Yanny , Nick Antipa , William Liberti , Sam Dehaeck , Kristina Monakhova , Fanglin Linda Liu , Konlin Shen , Ren Ng , Laura Waller

Super-resolution microscopy is crucial for imaging sub-wavelength biological structures. However, most techniques rely on nonlinear saturation or stochastic switching of emitters, limiting imaging speed and increasing phototoxicity. Here,…

Lidars and cameras are critical sensors that provide complementary information for 3D detection in autonomous driving. While most prevalent methods progressively downscale the 3D point clouds and camera images and then fuse the high-level…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Zixuan Yin , Han Sun , Ningzhong Liu , Huiyu Zhou , Jiaquan Shen

Acquiring high-contrast optical images deep inside biological tissues is still a challenging problem. Confocal microscopy is an important tool for biomedical imaging since it improves image quality by rejecting background signals. However,…

Lensless imaging enables exceptionally compact fluorescence sensors, advancing applications in \textit{in vivo} imaging and low-cost, point-of-care diagnostics. These sensors require a filter to block the excitation light while passing…

Image and Video Processing · Electrical Eng. & Systems 2026-02-20 Lukas Harris , Micah Roschelle , Jack Bartley , Mekhail Anwar

This paper introduces a novel method to super-resolve multi-spectral images captured by modern real-time single-shot mosaic image sensors, also known as multi-spectral cameras. Our contribution is two-fold. Firstly, we super-resolve…

Image and Video Processing · Electrical Eng. & Systems 2019-11-07 Mehrdad Shoeiby , Sadegh Aliakbarian , Saeed Anwar , Lars Petersson

Synthetic aperture imaging has enabled breakthrough observations from radar to astronomy. However, optical implementation remains challenging due to stringent wavefield synchronization requirements among multiple receivers. Here we present…

Fluorescence microscopy is widely employed for the analysis of living biological samples; however, the utility of the resulting recordings is frequently constrained by noise, temporal variability, and inconsistent visualisation of signals…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Hassan Eshkiki , Sarah Costa , Mostafa Mohammadpour , Farinaz Tanhaei , Christopher H. George , Fabio Caraffini

Wide-field imaging is widely adopted due to its fast acquisition, cost-effectiveness and ease of use. Its extension to direct volumetric applications, however, is burdened by the trade-off between resolution and depth of field (DOF),…

Fourier-based optical computing operations, such as spatial differentiation, have recently been realized in compact form factors using flat optics. Experimental demonstrations, however, have been limited to coherent light requiring laser…

Optics · Physics 2021-12-07 Xiaomeng Zhang , Benfeng Bai , Hong-Bo Sun , Guofan Jin , Jason Valentine

Hyperspectral cameras face harsh trade-offs between spatial, spectral, and temporal resolution in inherently low-photon conditions. Computational imaging systems break through these trade-offs with compressive sensing, but have required…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 M. Kerem Aydin , Yi-Chun Hung , Jaclyn Pytlarz , Qi Guo , Emma Alexander

Purpose: Hyperpolarized imaging experiments have conflicting requirements of high spatial, temporal, and spectral resolution. Spectral-Spatial RF excitation has been shown to form an attractive magnetization-efficient method for…

Photoacoustic imaging (PAI) is a novel hybrid imaging technique that combines the benefits of both optical and acoustic imaging modalities, which provides functional and molecular optical contrasts of deep tissue. Commonly used ultrasound…

Medical Physics · Physics 2025-09-24 Xiyu Chen , Junxiang Cai , Rui Zheng , Tao Wu , Fei Gao

Accurate and fast 3D imaging of specular surfaces still poses major challenges for state-of-the-art optical measurement principles. Frequently used methods, such as phase-measuring deflectometry (PMD) or shape-from-polarization (SfP), rely…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Jiazhang Wang , Oliver Cossairt , Florian Willomitzer

On-chip optical architectures that enable angle-resolved spectroscopy are essential for advancing photonic platforms towards low-volume, scalable, and cryo-compatible devices. Here, we introduce spatially resolved momentum-space imaging…

We introduce a compressive single-pixel imaging (SPI) framework for high-resolution image capture in fractions of a second. This framework combines a dedicated sampling strategy with a tailored reconstruction method to enable high-quality…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Anna Pastuszczak , Rafał Stojek , Piotr Wróbel , Magdalena Cwojdzińska , Kacper Sobczak , Rafał Kotyński