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A mathematical model for fluid transport in peritoneal dialysis is constructed. The model is based on a three-component nonlinear system of two-dimensional partial differential equations for fluid, glucose and albumin transport with the…

Analysis of PDEs · Mathematics 2011-10-07 Roman Cherniha , Jacek Waniewski

Mathematical modeling is an important theoretical tool which provides researchers with quantification of the permeability of dialyzing systems in renal replacement therapy. In the paper we provide a short review of the most successful…

Tissues and Organs · Quantitative Biology 2018-05-16 Marina V Voinova

Diffusion models are important in tissue engineering as they enable an understanding of molecular delivery to cells in tissue constructs. As three-dimensional (3D) tissue constructs become larger, more intricate, and more clinically…

Tissues and Organs · Quantitative Biology 2015-12-22 Richard J. McMurtrey

Local drug delivery has received much recognition in recent years, yet it is still unpredictable how drug efficacy depends on physicochemical properties and delivery kinetics. The purpose of the current study is to provide a useful…

Dynamical Systems · Mathematics 2016-01-26 Koyel Chakravarty , D C Dalal

We present a unified mathematical framework for modeling blood and lymph flow in biological vessels, with a particular focus on lymph transport through lymphangions. Starting from first principles, we rigorously derive a system of partial…

Analysis of PDEs · Mathematics 2026-03-03 Bogna Jaszczak-Dyka , Łukasz Płociniczak

Physiological whole-body models are valuable tools for the development of novel drugs where understanding the system aspects is important. This paper presents a generalized model that encapsulates the structure and flow of whole-body human…

Quantitative Methods · Quantitative Biology 2024-04-23 Laura Hjort Blicher , Peter Emil Carstensen , Jacob Bendsen , Henrik Linden , Bjørn Hald , Kim Kristensen , John Bagterp Jørgensen

In this paper, we extend previous work on the mathematical modeling of oxygen transport in biological tissues (Matzavinos et al., 2009). Specifically, we include in the modeling process the arterial and venous microstructure within the…

Analysis of PDEs · Mathematics 2015-07-30 Anastasios Matzavinos , Mariya Ptashnyk

In this paper, we derive an effective model for transport processes in periodically perforated elastic media, taking into account, e.g., cyclic elastic deformations as they occur in lung tissue due to respiratory movement. The underlying…

Analysis of PDEs · Mathematics 2022-06-15 Jonas Knoch , Markus Gahn , Maria Neuss-Radu , Nicolas Neuß

In recent years, research and development in nanoscale science and technology have grown significantly, with electrical transport playing a key role. A natural challenge for its description is to shed light on anomalous behaviours observed…

Populations and Evolution · Quantitative Biology 2025-04-10 Sara Bernardi , Paolo Begnamino , Marco Pizzi , Lamberto Rondoni

Microdialysis is a well-established method for in vivo neurochemical measurements of small molecules, with implanted concentric-design probes offering minimized tissue damage and good temporal and spatial resolution. However, the large…

Quantitative Methods · Quantitative Biology 2021-09-10 Damon Vinciguerra , Margot Vigeant , Ewan C. McNay

A vibrational model of transport properties of dense fluids assumes that solid-like oscillations of atoms around their temporary equilibrium positions dominate the dynamical picture. The temporary equilibrium positions of atoms do not form…

Soft Condensed Matter · Physics 2024-01-09 Sergey Khrapak

An oxidation process is simulated for a bundle of metal tubes in a cross-flow. A fluid flow is governed by the incompressible Navier-Stokes equations. To describe the transport of oxygen, the corresponding convection-diffusion equation is…

Computational Engineering, Finance, and Science · Computer Science 2017-08-15 Alexander G. Churbanov , Oleg Iliev , Valery F. Strizhov , Petr N. Vabishchevich

The flow simulation in alveolar region is imperative in understanding transport of particles and designing aerosol drug delivery systems. Air flow is dependent on alveolar geometry and ventilation conditions. In this work a three…

Fluid Dynamics · Physics 2018-06-04 M. Monjezi , A. Rouhollahi , M. S. Saidi , B. M. Afshary

The primary exchange units in the human placenta are terminal villi, in which fetal capillary networks are surrounded by a thin layer of villous tissue, separating fetal from maternal blood. To understand how the complex spatial structure…

Tissues and Organs · Quantitative Biology 2019-09-12 Alexander Erlich , Gareth A. Nye , Paul Brownbill , Oliver E. Jensen , Igor L. Chernyavsky

The paper deals with modeling the liver perfusion intended to improve quantitative analysis of the tissue scans provided by the contrast-enhanced computed tomography (CT). For this purpose, we developed a model of dynamic transport of the…

Computational Engineering, Finance, and Science · Computer Science 2018-08-01 Eduard Rohan , Vladimír Lukeš , Alena Jonášová

Esophageal transport is a physiological process that mechanically transports an ingested food bolus from the pharynx to the stomach via the esophagus, a multi-layered muscular tube. This process involves interactions between the bolus, the…

An accurate modeling of reactive flows in fractured porous media is a key ingredient to obtain reliable numerical simulations of several industrial and environmental applications. For some values of the physical parameters we can observe…

Numerical Analysis · Mathematics 2020-11-10 Luca Formaggia , Alessio Fumagalli , Anna Scotti

This paper considers particle propagation in a cylindrical molecular communication channel, e.g. a simplified model of a blood vessel. Emitted particles are influenced by diffusion, flow, and a vertical force induced e.g. by gravity or…

Computational Physics · Physics 2019-02-26 Maximilian Schäfer , Wayan Wicke , Rudolf Rabenstein , Robert Schober

On the basis of local nonequilibrium approach, the one-dimensional model of the solute diffusion during rapid solidification of the binary alloy in the semi-infinite volume is considered. Within the scope of the model it is supposed that…

Materials Science · Physics 2009-12-23 G. L. Buchbinder , P. Martaller

We describe a mathematical modeling of the digestion in the small intestine. The main interest of our work is to consider, at the same time, different aspects of the digestion i.e. the transport of the bolus all along the intestine,…

Dynamical Systems · Mathematics 2011-11-22 Masoomeh Taghipoor , Philippe Lescoat , Christine Georgelin , Jean-René Licois , Guy Barles
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