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Factorial designs are often used in various industrial and sociological experiments to identify significant factors and factor combinations that may affect the process response. In the statistics literature, several studies have…

Methodology · Statistics 2020-12-16 Pratishtha Batra , Neil A. Spencer , Pritam Ranjan

Regular factorial designs with randomization restrictions are widely used in practice. This paper provides a unified approach to the construction of such designs using randomization defining contrast subspaces for the representation of…

Statistics Theory · Mathematics 2009-09-03 Pritam Ranjan , Derek R. Bingham , Angela M. Dean

Experiments using multi-step protocols often involve several restrictions on the randomization. For a specific application to in vitro testing on microplates, a design was required with both a split-plot and a strip-plot structure. On top…

Factorial designs are widely used in agriculture, engineering, and the social sciences to study the causal effects of several factors simultaneously on a response. The objective of such a design is to estimate all factorial effects of…

Methodology · Statistics 2015-11-09 Zach Branson , Tirthankar Dasgupta , Donald B. Rubin

Two-level factorial designs are widely used in industrial experiments. For processes involving \(n\) factors, the construction of designs comprising \(2^n\) and \(2^{n-p}\) factorials, arranged in blocks of size \(2^q\) is investigated. The…

Statistics Theory · Mathematics 2019-07-05 Janet Godolphin

Factorial designs have broad applications in agricultural, engineering and scientific studies. In constructing and studying properties of factorial designs, traditional design theory treats all factors as nominal. However, this is not…

Statistics Theory · Mathematics 2007-06-13 Shao-Wei Cheng , Kenny Q. Ye

Fractional factorial designs are widely used for designing screening experiments. Nonregular fractional factorial designs can have better properties than regular designs, but their construction is challenging. Current research on the…

Methodology · Statistics 2021-06-02 Lin Wang , Hongquan Xu

Factorial designs are frequently used in different fields of science, e.g. psychological, medical or biometric studies. Standard approaches, as the ANOVA $F$-test, make different assumptions on the distribution of the error terms, the…

Methodology · Statistics 2018-02-21 Maria Umlauft

With many pretreatment covariates and treatment factors, the classical factorial experiment often fails to balance covariates across multiple factorial effects simultaneously. Therefore, it is intuitive to restrict the randomization of the…

Statistics Theory · Mathematics 2018-12-31 Xinran Li , Peng Ding , Donald B. Rubin

Systematic differences in experimental materials, methods, measurements, and data handling between labs, over time, and among personnel can sabotage experimental reproducibility. Uncovering such differences can be difficult and time…

Applications · Statistics 2018-07-18 Bert Gunter

Split-plot or repeated measures designs are frequently used for planning experiments in the life or social sciences. Typical examples include the comparison of different treatments over time, where both factors may possess an additional…

Statistics Theory · Mathematics 2017-10-13 Maria Umlauft , Marius Placzek , Frank Konietschke , Markus Pauly

In this paper we study saturated fractions of factorial designs under the perspective of Algebraic Statistics. We define a criterion to check whether a fraction is saturated or not with respect to a given model. The proposed criterion is…

Statistics Theory · Mathematics 2013-05-01 Roberto Fontana , Fabio Rapallo , Maria-Piera Rogantin

In this article, an adaption of an algorithm for the creation of experimental designs by Lekivetz and Jones (2015) is suggested, dealing with constraints around randomization. Split-plot design of experiments is used, when the levels of…

Methodology · Statistics 2020-03-24 Thomas Muehlenstaedt , Maria Lanzerath

Designs for screening experiments usually include factors with two levels only. Adding a few four-level factors allows for the inclusion of multi-level categorical factors or quantitative factors with possible quadratic or third-order…

Methodology · Statistics 2023-05-11 Alexandre Bohyn , Eric D. Schoen , Peter Goos

The aim of this paper is to review methods of designing screening experiments, ranging from designs originally developed for physical experiments to those especially tailored to experiments on numerical models. The strengths and weaknesses…

Methodology · Statistics 2015-10-20 David C. Woods , Susan M. Lewis

For large classes of group testing problems, we derive lower bounds for the probability that all significant items are uniquely identified using specially constructed random designs. These bounds allow us to optimize parameters of the…

Statistics Theory · Mathematics 2022-02-17 Jack Noonan , Anatoly Zhigljavsky

Unreplicated two-level factorial designs are often used in screening experiments to determine which factors out of a large plausible set are active. A theorem regarding the generalized word count pattern is stated and proved for…

Methodology · Statistics 2025-10-14 Xietao Zhou , Steven G. Gilmour

Typically, trials investigate the impact of either an individual-level intervention on participant outcomes, or the impact of a cluster-level intervention on participant outcomes. Factorial designs consider two (or more) treatments for each…

Methodology · Statistics 2026-05-04 Rhys Bowden , Rebecca Walwyn , Jessica Kasza , Andrew Copas , Fan Li , James Wason , Andrew Forbes

An {\em $m\times n$ row-column factorial design} is an arrangement of the elements of a factorial design into a rectangular array. Such an array is used in experimental design, where the rows and columns can act as blocking factors. If for…

Statistics Theory · Mathematics 2021-01-18 Fahim Rahim , Nicholas Cavenagh

Given two 2-level factors of interest, a 2^2 split-plot design} (a) takes each of the $2^2=4$ possible factorial combinations as a treatment, (b) identifies one factor as `whole-plot,' (c) divides the experimental units into blocks, and (d)…

Methodology · Statistics 2016-02-15 Anqi Zhao , Peng Ding , Tirthankar Dasgupta
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