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Droplets form a cornerstone of the spatiotemporal organization of biomolecules in cells. These droplets are controlled using physical processes like chemical reactions and imposed gradients, which are costly to simulate using traditional…

Soft Condensed Matter · Physics 2022-06-23 Ajinkya Kulkarni , Estefania Vidal-Henriquez , David Zwicker

We numerically investigate how spatial variations of extensile or contractile active stress affect bulk active nematic systems in two and three dimensions. In the absence of defects, activity gradients drive flows which re-orient the…

Soft Condensed Matter · Physics 2022-06-15 Liam J Ruske , Julia M Yeomans

Spontaneous motion of an oil droplet driven by chemical nonequilibricity is reported. It is shown that the droplet undergoes regular rhythmic motion under appropriately designed boundary conditions, whereas it exhibits random motion in an…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Yutaka Sumino , Nobuyuki Magome , Tsutomu Hamada , Kenichi Yoshikawa

Recent advances in cell biology and experimental techniques using reconstituted cell extracts have generated significant interest in understanding how geometry and topology influence active fluid dynamics. In this work, we present a…

Soft Condensed Matter · Physics 2024-05-13 Cuncheng Zhu , David Saintillan , Albert Chern

We investigate experimentally the behavior of self-propelled water-in-oil droplets, confined in capillaries of different square and circular cross-sections. The droplet's activity comes from the formation of swollen micelles at its…

Soft Condensed Matter · Physics 2021-10-05 Charlotte de Blois , Vincent Bertin , Saori Suda , Masatoshi Ichikawa , Mathilde Reyssat , Olivier Dauchot

We introduce a general description of localised distortions in active nematics using the framework of active nematic multipoles. We give the Stokesian flows for arbitrary multipoles in terms of differentiation of a fundamental flow response…

Soft Condensed Matter · Physics 2023-04-04 Alexander J. H. Houston , Gareth P. Alexander

Using computer simulations we investigate the microscopic structure of the singular director field within a nematic droplet. As a theoretical model for nematic liquid crystals we take hard spherocylinders. To induce an overall topological…

Soft Condensed Matter · Physics 2009-10-31 J. Dzubiella , M. Schmidt , H. Loewen

Phase separating systems that are maintained away from thermodynamic equilibrium via molecular processes represent a class of active systems, which we call active emulsions. These systems are driven by external energy input for example…

Soft Condensed Matter · Physics 2019-06-07 Christoph A. Weber , David Zwicker , Frank Jülicher , Chiu Fan Lee

Recent experiments on active materials, such as dense bacterial suspensions and microtubule-kinesin motor mixtures, show a promising potential for achieving self-sustained flows. However, to develop active microfluidics it is necessary to…

Soft Condensed Matter · Physics 2019-01-23 Santhan Chandragiri , Amin Doostmohammadi , Julia M Yeomans , Sumesh P Thampi

Nonlinear phenomena including multiple equilibria and spontaneous oscillations are common in fluid networks containing either multiple phases or constituent flows. In many systems, such behavior might be attributed to the complicated…

Dynamical Systems · Mathematics 2013-06-26 Nathaniel J. Karst , Brian D. Storey , John B. Geddes

The structure of a molecular liquid, in both the nematic liquid crystalline and isotropic phases, around a cylindrical macroparticle, is studied using density functional theory. In the nematic phase the structure of the fluid is highly…

Soft Condensed Matter · Physics 2009-11-11 David L. Cheung , Michael P. Allen

We present a hydrodynamic model for a thin spherical shell of active nematic liquid crystal with an arbitrary configuration of defects. The active flows generated by defects in the director lead to the formation of stable vortices,…

Soft Condensed Matter · Physics 2017-11-13 Diana Khoromskaia , Gareth P. Alexander

Active nematics are the nonequilibrium analog of passive liquid crystals in which anisotropic units consume free energy to drive emergent behavior. Similar to liquid crystal (LC) molecules in displays, ordering and dynamics in active…

Quantitative Methods · Quantitative Biology 2022-10-10 Japinder Nijjer , Mrityunjay Kothari , Changhao Li , Thomas Henzel , Qiuting Zhang , Jung-Shen B. Tai , Shuang Zhou , Sulin Zhang , Tal Cohen , Jing Yan

Two-dimensional active nematics are often modeled using phenomenological continuum theories that describe the dynamics of the nematic director and fluid velocity through partial differential equations (PDEs). While these models provide a…

A body immersed in a nematic liquid crystal disturbs the fluid's preferred molecular configuration and increases its stored elastic energy. In an active nematic, the fluid components also generate a stress in the bulk fluid. By introducing…

Soft Condensed Matter · Physics 2025-06-17 Thomas G. J. Chandler , Saverio E. Spagnolie

Recent experiments in various cell types have shown that two-dimensional tissues often display local nematic order, with evidence of extensile stresses manifest in the dynamics of topological defects. Using a mesoscopic model where tissue…

Soft Condensed Matter · Physics 2021-03-30 Farzan Vafa , Mark J. Bowick , Boris I. Shraiman , M. Cristina Marchetti

We report an experimental investigation of the spontaneous motion of liquid droplets on soft gels with a crosslinking gradient. By systematically adjusting the spatial difference in crosslinking density, we observed that millimeter-sized…

Soft Condensed Matter · Physics 2025-01-29 Weiwei Zhao , Wenjie Qian , Chang Xu , Qin Xu

Numerous physical models have been proposed to explain how cell motility emerges from internal activity, mostly focused on how crawling motion arises from internal processes. Here we offer a classification of self-propulsion mechanisms…

Soft Condensed Matter · Physics 2020-03-05 Aurore Loisy , Jens Eggers , Tanniemola B. Liverpool

We study how confinement transforms the chaotic dynamics of bulk microtubule-based active nematics into regular spatiotemporal patterns. For weak confinements, multiple continuously nucleating and annihilating topological defects…

Confining a liquid crystal imposes topological constraints on the orientational order, allowing global control of equilibrium systems by manipulation of anchoring boundary conditions. In this article, we investigate whether a similar…