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PET is a functional imaging technique based on detection of annihilation photons following beta decay producing positrons. In this paper, we present the concept of a new PET system for preclinical applications consisting of a ring of twelve…

Instrumentation and Detectors · Physics 2015-03-19 A. Miceli , P. Amaudruz , F. Benard , D. A. Bryman , L. Kurchaninov , J. P. Martin , A. Muennich , F. Retiere , T. J. Ruth , V. Sossi , A. J. Stoessl

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yeqi Fang , Rong Zhou

In positron emission tomography (PET) imaging, statistical iterative reconstruction (IR) techniques appear particularly promising since they can provide accurate system model. The system model matrix which describes the relationship between…

Small animal PET scanners require high spatial resolution and good sensitivity. To reconstruct high-resolution images in 3D-PET, iterative methods, such as OSEM, are superior to analytical reconstruction algorithms, although their high…

Medical Physics · Physics 2007-05-23 J. L. Herraiz , S. Espana , J. J. Vaquero , M. Desco , J. M. Udias

Time-of-flight positron emission tomography (TOF-PET) detectors exhibiting multiple coincidence time resolution (CTR) components, such as those induced by the mixing of Cherenkov and scintillation photons, have attracted increasing…

Medical Physics · Physics 2026-05-29 Kibo Ote , Fumio Hashimoto , Yuya Onishi , Ryosuke Ota , Maxime Toussaint , Francis Loignon-Houle

Positron Emission Tomography (PET) is a Nuclear Medicine technique that creates images that allow the study of metabolic activity and organ function using radiopharmaceuticals. Continuous improvement of scintillation detectors for radiation…

We present first results from a Positron Emission Tomography (PET) scanner demonstrator based on Resistive Plate Chambers and specialized for brain imaging. The device features a 30 cm wide cubic field-of-view and each detector comprises 40…

The integration of Time-of-Flight (TOF) information in the reconstruction process of Positron Emission Tomography (PET) yields improved image properties. However, implementing the cutting-edge model-based deep learning methods for TOF-PET…

Image and Video Processing · Electrical Eng. & Systems 2023-02-22 Chenxu Li , Rui Hu , Jianan Cui , Huafeng Liu

The kernel reconstruction is a method that reduces noise in dynamic positron emission tomography (PET) by exploiting spatial correlations in the PET image. Although this method works well for large anatomical regions with relatively slow…

Medical Physics · Physics 2025-07-31 Alan Miranda , Steven Staelens

Currently inorganic scintillator detectors are used in all commercial Time of Flight Positron Emission Tomograph (TOF-PET) devices. The J-PET collaboration investigates a possibility of construction of a PET scanner from plastic…

Positron emission tomography (PET) suffers from severe resolution limitations which limit its quantitative accuracy. In this paper, we present a super-resolution (SR) imaging technique for PET based on convolutional neural networks (CNNs).…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Tzu-An Song , Samadrita Roy Chowdhury , Fan Yang , Joyita Dutta

Positron Emission Mammography (PEM) imaging systems with the ability in detection of millimeter-sized tumors were developed in recent years. And some of them have been well used in clinical applications. In consideration of biopsy…

Medical Physics · Physics 2016-08-03 Xiao-Yue Gu , Wei Zhou , Lin Li , Peng-Fei Yin , Lei-Min Shang , Ming-Kai Yun , Zhen-Rui Lu , Xian-Chao Huang , Long Wei

Positron emission tomography (PET) imaging is widely used in a number of clinical applications, including cancer and Alzheimer's disease (AD) diagnosis, monitoring of disease development, and treatment effect evaluation. Statistical…

Tissues and Organs · Quantitative Biology 2025-11-07 Akhil Ambekar , Robert Zielinski , Ani Eloyan

Positron emission tomography(PET) image reconstruction is an ill-posed inverse problem and suffers from high level of noise due to limited counts received. Recently deep neural networks especially convolutional neural networks(CNN) have…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Rui Hu , Huafeng Liu

In this paper we consider the problem of reconstructing an image that is downsampled in the space of its $SE(2)$ wavelet transform, which is motivated by classical models of simple cells receptive fields and feature preference maps in…

Numerical Analysis · Mathematics 2021-10-05 Davide Barbieri

Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Jie Sun , Junyan Zhang , Qian Xia , Chuanfu Sun , Yumei Chen , Yunjie Yang , Huafeng Liu , Wentao Zhu , Qiegen Liu

Dynamic positron emission tomography (dPET) image reconstruction is extremely challenging due to the limited counts received in individual frame. In this paper, we propose a spatial-temporal convolutional primal dual network (STPDnet) for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Rui Hu , Jianan Cui , Chengjin Yu , Yunmei Chen , Huafeng Liu

In this paper, we provide a precise mathematical model of crystal-to-crystal response which is used to generate the white image - a necessary compensation model needed to overcome the physical limitations of the PET scanner. We present a…

Signal Processing · Electrical Eng. & Systems 2026-02-18 Tomislav Matulić , Damir Seršić

This paper reviewed the machine learning-based studies for quantitative positron emission tomography (PET). Specifically, we summarized the recent developments of machine learning-based methods in PET attenuation correction and low-count…

Image and Video Processing · Electrical Eng. & Systems 2020-01-22 Tonghe Wang , Yang Lei , Yabo Fu , Walter J. Curran , Tian Liu , Xiaofeng Yang

This work aims at applying the theory of the component-based normalization for the Jagiellonian PET scanner, currently under development at the Jagiellonian University. In any Positron Emission Tomography acquisition, efficiency along a…

Medical Physics · Physics 2024-09-04 Aurélien Coussat , Wojciech Krzemien , Jakub Baran , Szymon Parzych