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Molecular chaperones play a prominent role in signaling and transcriptional regulatory networks of the cell. Recent advances uncovered that chaperones act as genetic buffers stabilizing the phenotype of various cells and organisms and may…

Molecular Networks · Quantitative Biology 2007-05-23 Tamas Korcsmaros , Istvan A. Kovacs , Mate S. Szalay , Peter Csermely

We analyse the neural dynamics and its relation with the emergent behaviour of a robotic vehicle that is controlled by a neural network numerical simulation based on the nervous system of the nematode Caenorhabditis elegans. The robot…

Neurons and Cognition · Quantitative Biology 2020-11-19 Carlos E. Valencia Urbina , Sergio A. Cannas , Pablo M. Gleiser

Recent experiments on the green alga Chlamydomonas that swims using synchronized beating of a pair of flagella have revealed that it exhibits a run-and-tumble behavior similar to that of bacteria such as E. Coli. Using a simple purely…

Cell Behavior · Quantitative Biology 2015-06-12 Rachel R. Bennett , Ramin Golestanian

In the last century, most sensorimotor studies of cortical neurons relied on average firing rates. Rate coding is efficient for fast sensorimotor processing that occurs within a few seconds. Much less is known about the neural mechanisms…

Neurons and Cognition · Quantitative Biology 2026-05-01 Terrence J. Sejnowski

We uncover a new type of turbulence -- activity-induced homogeneous and isotropic turbulence in a model that has been employed to investigate motility-induced phase separation (MIPS) in a system of microswimmers. The active…

Fluid Dynamics · Physics 2024-02-05 Nadia Bihari Padhan , Kolluru Venkata Kiran , Rahul Pandit

The millimeter-long soil-dwelling nematode {\it C. elegans} propels itself by producing undulations that propagate along its body and turns by assuming highly curved shapes. According to our recent study [PLoS ONE \textbf{7}, e40121 (2012)]…

Fluid Dynamics · Physics 2019-01-18 Alejandro Bilbao , Eligiusz Wajnryb , Siva Vanapalli , Jerzy Blawzdziewicz

Molecular networks act as the backbone of cellular activities, providing an {excellent} opportunity to understand the developmental changes in an organism. While network data usually constitute only stationary network graphs, constructing…

Molecular Networks · Quantitative Biology 2016-02-29 Pramod Shinde , Sarika Jalan

Neuronal ensemble activity, including coordinated and oscillatory patterns, exhibits hallmarks of nonequilibrium systems with time-asymmetric trajectories to maintain their organization. However, assessing time asymmetry from neuronal…

Neurons and Cognition · Quantitative Biology 2025-12-12 Ken Ishihara , Hideaki Shimazaki

Compliant robots can be more versatile than traditional robots, but their control is more complex. The dynamics of compliant bodies can however be turned into an advantage using the physical reservoir computing frame-work. By feeding sensor…

Neural and Evolutionary Computing · Computer Science 2020-04-15 Alexander Vandesompele , Gabriel Urbain , Francis wyffels , Joni Dambre

Interacting individuals in complex systems often give rise to coherent motion exhibiting coordinated global structures. Such phenomena are ubiquitously observed in nature, from cell migration, bacterial swarms, animal and insect groups, and…

Neural and Evolutionary Computing · Computer Science 2024-07-17 Dongjo Kim , Jeongsu Lee , Ho-Young Kim

In this study, we utilize genetic algorithms to develop a realistic implicit solvent ultra-coarse-grained (PC) membrane model comprising only three interaction sites. The key philosophy of the ultra-CG membrane model SMARTINI3 is its…

Biomolecules · Quantitative Biology 2024-05-10 Alireza Soleimani , Herre Jelger Risselada

Reverberating dynamics of neural network is modelled on PC in order to illustrate possible role of inhibition as binding controller in the network. The network is composed of binding neurons. In the binding neuron model the degree of…

Neurons and Cognition · Quantitative Biology 2013-05-17 Alexander Vidybida

Epilepsy is a common neurological disorder characterized by recurrent seizures accompanied by excessive synchronous brain activity. The process of structural and functional brain alterations leading to increased seizure susceptibility and…

Signal Processing · Electrical Eng. & Systems 2020-06-18 Diyuan Lu , Sebastian Bauer , Valentin Neubert , Lara Sophie Costard , Felix Rosenow , Jochen Triesch

The complex formations exhibited by schooling fish have long been the object of fascination for biologists and physicists. However, the physical and sensory mechanisms leading to organized collective behavior remain elusive. On the physical…

Fluid Dynamics · Physics 2025-07-09 Anand U. Oza , Eva Kanso , Michael J. Shelley

In this letter, we formulate a novel Markov Decision Process (MDP) for safe and data-efficient learning for humanoid locomotion aided by a dynamic balancing model. In our previous studies of biped locomotion, we relied on a low-dimensional…

Robotics · Computer Science 2020-04-29 Junhyeok Ahn , Jaemin Lee , Luis Sentis

Partial synchronization plays a crucial role in the functioning of neuronal networks: selective, coordinated activation of neurons enables information processing that flexibly adapts to a changing computational context. Since the structure…

Neurons and Cognition · Quantitative Biology 2025-06-17 Daniil Radushev , Olesia Dogonasheva , Boris Gutkin , Denis Zakharov

In active matter systems, self-propelled particles can self-organize to undergo collective motion, leading to persistent dynamical behavior out of equilibrium. In cells, cytoskeletal filaments and motor proteins self-organize into complex…

Soft Condensed Matter · Physics 2020-05-19 Jeffrey M. Moore , Tyler N. Thompson , Matthew A. Glaser , Meredith D. Betterton

How the information microscopically processed by individual neurons is integrated and used in organizing the behavior of an animal is a central question in neuroscience. The coherence of neuronal dynamics over different scales has been…

Disordered Systems and Neural Networks · Physics 2020-03-11 Takashi Hayakawa , Tomoki Fukai

Cortical activity in-vivo displays relaxational time scales much longer than the membrane time constant of the neurons or the deactivation time of ionotropic synaptic conductances. The mechanisms responsible for such slow dynamics are not…

Disordered Systems and Neural Networks · Physics 2025-08-07 Ferdinand Tixidre , Gianluigi Mongillo , Alessandro Torcini

The combination of new recording techniques in neuroscience and powerful inference methods recently held the promise to recover useful effective models, at the single neuron or network level, directly from observed data. The value of a…

Neurons and Cognition · Quantitative Biology 2018-04-09 Cristiano Capone , Guido Gigante , Paolo Del Giudice