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Many active biological particles, such as swimming microorganisms or motor-proteins, do work on their environment by going though a periodic sequence of shapes. Interactions between particles can lead to the phase-synchronization of their…

Soft Condensed Matter · Physics 2022-07-26 Brato Chakrabarti , Michael J. Shelley , Sebastian Fürthauer

Large cells often rely on cytoplasmic flows for intracellular transport, maintaining homeostasis, and positioning cellular components. Understanding the mechanisms of these flows is essential for gaining insights into cell function,…

Fluid Dynamics · Physics 2023-11-09 Brato Chakrabarti , Stanislav Y. Shvartsman , Michael J. Shelley

Meso-scale turbulence was originally observed experimentally in various suspensions of swimming bacteria, as well as in the collective motion of active colloids. The corresponding large-scale dynamical patterns were reproduced in a simple…

Soft Condensed Matter · Physics 2021-03-30 Vasco M. Worlitzer , Gil Ariel , Avraham Be'er , Holger Stark , Markus Bär , Sebastian Heidenreich

The unicellular green algae Chlamydomonas swims with two flagella, which can synchronize their beat. Synchronized beating is required to swim both fast and straight. A long-standing hypothesis proposes that synchronization of flagella…

Cell Behavior · Quantitative Biology 2013-11-26 Veikko Geyer , Frank Jülicher , Jonathon Howard , Benjamin M Friedrich

Computational approaches which emulate in-vivo nervous system are needed to investigate mechanisms of the brain to orchestrate behavior. Such approaches must integrate a series of biophysical models encompassing the nervous system, muscles,…

Quantitative Methods · Quantitative Biology 2025-06-05 Jimin Kim , Jeremy T. Florman , Julia A. Santos , Mark J. Alkema , Eli Shlizerman

Balance of excitation and inhibition is a fundamental feature of in vivo network activity and is important for its computations. However, its presence in the neocortex of higher mammals is not well established. We investigated the dynamics…

Cerebellar-like networks, in which input activity patterns are separated by projection to a much higher-dimensional space before classification, are a recurring neurobiological motif, present in the cerebellum, dentate gyrus, insect…

Neurons and Cognition · Quantitative Biology 2026-03-23 William Dorrell , Peter E. Latham

Brain research has been driven by enquiry for principles of brain structure organization and its control mechanisms. The neuronal wiring map of C. elegans, the only complete connectome available till date, presents an incredible opportunity…

Neurons and Cognition · Quantitative Biology 2016-11-28 Rahul Badhwar , Ganesh Bagler

The internal dynamics of active gels, both in artificial (in-vitro) model systems and inside the cytoskeleton of living cells, has been extensively studied by experiments of recent years. These dynamics are probed using tracer particles…

Soft Condensed Matter · Physics 2015-07-28 E. Ben Isaac , É. Fodor , P. Visco , F. van Wijland , N. S. Gov

Active fluids, such as cytoskeletal filaments, bacterial colonies and epithelial cell layers, exhibit distinctive orientational coherence, often characterized by nematic order and topological defects. By contrast, little is known about…

Soft Condensed Matter · Physics 2021-04-07 Mattia Serra , Linnea Lemma , Luca Giomi , Zvonimir Dogic , L. Mahadevan

By means of computer simulations and solution of the equations of the Mode Coupling Theory (MCT), we investigate the role of the intramolecular barriers on several dynamic aspects of non-entangled polymers. The investigated dynamic range…

Soft Condensed Matter · Physics 2015-05-18 Marco Bernabei , Angel J. Moreno , Emanuela Zaccarelli , Francesco Sciortino , Juan Colmenero

We propose an architecture for learning complex controllable behaviors by having simple Policies Modulate Trajectory Generators (PMTG), a powerful combination that can provide both memory and prior knowledge to the controller. The result is…

Robotics · Computer Science 2019-10-08 Atil Iscen , Ken Caluwaerts , Jie Tan , Tingnan Zhang , Erwin Coumans , Vikas Sindhwani , Vincent Vanhoucke

Automated verification of living organism models allows us to gain previously unknown knowledge about underlying biological processes. In this paper, we show the benefits to use parametric time Petri nets in order to analyze precisely the…

Logic in Computer Science · Computer Science 2015-06-23 Alexander Andreychenko , Morgan Magnin , Katsumi Inoue

Large-scale neuroscience is generating rich datasets across animals, brain areas and behavioral contexts, yet our modeling efforts remains fragmented across isolated experiments. We argue that understanding behavior requires integrative…

Active nematics are out-of-equilibrium systems in which energy injection at the microscale drives emergent collective behaviors, from spontaneous flows to active turbulence. While the dynamics of these systems have been extensively studied,…

Soft Condensed Matter · Physics 2025-04-15 Ahmet Umut Akduman , Yusuf Sariyar , Giuseppe Negro , Livio Nicola Carenza

Advances in legged robotics are strongly rooted in animal observations. A clear illustration of this claim is the generalization of Central Pattern Generators (CPG), first identified in the cat spinal cord, to generate cyclic motion in…

Robotics · Computer Science 2020-03-23 Gabriel Urbain , Victor Barasuol , Claudio Semini , Joni Dambre , Francis wyffels

Chiral active particles, or self-propelled circle swimmers, from sperm cells to asymmetric Janus colloids, form a rich set of patterns, which are different from those seen in linear swimmers. Such patterns have mainly been explored for…

Soft Condensed Matter · Physics 2019-07-24 Demian Levis , Benno Liebchen

Active networks composed of biopolymers and motor proteins provide versatile biomimetic systems that have advanced active matter physics and deepened our understanding of cytoskeletal dynamics and self-organization under diverse stimuli. In…

Planktonic copepods are small crustaceans that have the ability to swim by quick powerful jumps. Such an aptness is used to escape from high shear regions, which may be caused either by flow per- turbations, produced by a large predator…

As a person learns a new skill, distinct synapses, brain regions, and circuits are engaged and change over time. In this paper, we develop methods to examine patterns of correlated activity across a large set of brain regions. Our goal is…

Neurons and Cognition · Quantitative Biology 2013-10-31 Danielle S. Bassett , Nicholas F. Wymbs , M. Puck Rombach , Mason A. Porter , Peter J. Mucha , Scott T. Grafton