English
Related papers

Related papers: mTim: Rapid and accurate transcript reconstruction…

200 papers

In this work, we develop a novel technique for reconstructing images from projection-based nano- and microtomography. Our contribution focuses on enhancing reconstruction quality, particularly for specimen composed of homogeneous material…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Anuraag Mishra , Andrea Gilch , Benjamin Apeleo Zubiri , Jan Rolfes , Frauke Liers

In this paper, we introduce Writing in the Margins (WiM), a new inference pattern for Large Language Models designed to optimize the handling of long input sequences in retrieval-oriented tasks. This approach leverages the chunked prefill…

Computation and Language · Computer Science 2024-08-28 Melisa Russak , Umar Jamil , Christopher Bryant , Kiran Kamble , Axel Magnuson , Mateusz Russak , Waseem AlShikh

CLIP-seq methods are valuable techniques to experimentally determine transcriptome-wide binding sites of RNA-binding proteins. Despite the constant improvement of such techniques (e.g. eCLIP), the results are affected by various types of…

Biomolecules · Quantitative Biology 2024-12-31 Gianluca Corrado , Michael Uhl , Rolf Backofen , Andrea Passerini , Fabrizio Costa

Scanning electron microscopy (SEM) is indispensable in diverse applications ranging from microelectronics to food processing because it provides large depth-of-field images with a resolution beyond the optical diffraction limit. However,…

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

We present a novel end-to-end visual odometry architecture with guided feature selection based on deep convolutional recurrent neural networks. Different from current monocular visual odometry methods, our approach is established on the…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Fei Xue , Qiuyuan Wang , Xin Wang , Wei Dong , Junqiu Wang , Hongbin Zha

Designing protein sequences that fold into a target 3-D structure, termed as the inverse folding problem, is central to protein engineering. However, it remains challenging due to the vast sequence space and the importance of local…

Quantitative Methods · Quantitative Biology 2026-03-17 Sazan Mahbub , Souvik Kundu , Eric P. Xing

A great proportion of sequence-to-sequence (Seq2Seq) models for Neural Machine Translation (NMT) adopt Recurrent Neural Network (RNN) to generate translation word by word following a sequential order. As the studies of linguistics have…

Computation and Language · Computer Science 2018-06-14 Junyang Lin , Xu Sun , Xuancheng Ren , Shuming Ma , Jinsong Su , Qi Su

Person Re-Identification (re-id) is a challenging task in computer vision, especially when there are limited training data from multiple camera views. In this paper, we pro- pose a deep learning based person re-identification method by…

Computer Vision and Pattern Recognition · Computer Science 2016-11-21 Qiqi Xiao , Kelei Cao , Haonan Chen , Fangyue Peng , Chi Zhang

We demonstrate a multi-beam scanning transmission electron microscopy (STEM) imaging that integrates down-sampling with super-resolution image reconstruction via a compressive sensing framework. A custom condenser aperture with six randomly…

Instrumentation and Detectors · Physics 2026-03-19 Akira Yasuhara , Takumi Sannomiya , Ryoichi Horisaki

As high-throughput biological sequencing becomes faster and cheaper, the need to extract useful information from sequencing becomes ever more paramount, often limited by low-throughput experimental characterizations. For proteins, accurate…

Quantitative Methods · Quantitative Biology 2017-01-31 Xueliang Liu

Many of the current state-of-the-art Large Vocabulary Continuous Speech Recognition Systems (LVCSR) are hybrids of neural networks and Hidden Markov Models (HMMs). Most of these systems contain separate components that deal with the…

Computation and Language · Computer Science 2016-03-16 Dzmitry Bahdanau , Jan Chorowski , Dmitriy Serdyuk , Philemon Brakel , Yoshua Bengio

We present SMILES-embeddings derived from the internal encoder state of a Transformer [1] model trained to canonize SMILES as a Seq2Seq problem. Using a CharNN [2] architecture upon the embeddings results in higher quality interpretable…

Quantitative Methods · Quantitative Biology 2020-09-23 Pavel Karpov , Guillaume Godin , Igor V. Tetko

For sequence models with large vocabularies, a majority of network parameters lie in the input and output layers. In this work, we describe a new method, DeFINE, for learning deep token representations efficiently. Our architecture uses a…

Computation and Language · Computer Science 2020-02-07 Sachin Mehta , Rik Koncel-Kedziorski , Mohammad Rastegari , Hannaneh Hajishirzi

Deep neural networks for time series must capture complex temporal patterns, to effectively represent dynamic data. Self- and semi-supervised learning methods show promising results in pre-training large models, which -- when finetuned for…

Machine Learning · Computer Science 2025-08-15 Yuhan Xie , William Cappelletti , Mahsa Shoaran , Pascal Frossard

Currently, third-generation sequencing techniques, which allow to obtain much longer DNA reads compared to the next-generation sequencing technologies, are becoming more and more popular. There are many possibilities to combine data from…

Genomics · Quantitative Biology 2019-05-23 Wiktor Kuśmirek , Wiktor Franus , Robert Nowak

The spatial location of cells within tissues and organs is crucial for the manifestation of their specific functions.Spatial transcriptomics technology enables comprehensive measurement of the gene expression patterns in tissues while…

Quantitative Methods · Quantitative Biology 2024-07-12 Shuailin Xue , Fangfang Zhu , Changmiao Wang , Wenwen Min

Histopathology whole-slide images (WSIs) are routinely acquired in clinical practice and contain rich tissue morphology but lack direct molecular architecture and functional programs defining pathological states, whereas RNA sequencing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Yaxuan Song , Jianan Fan , Tianyi Wang , Qiuyue Hu , Hang Chang , Heng Huang , Weidong Cai

High-throughput sequencing of RNA transcripts (RNA-seq) has become the method of choice for detection of differential expression (DE). Concurrent with the growing popularity of this technology there has been a significant research effort…

Time series anomaly detection aims to identify unusual patterns in data or deviations from systems' expected behavior. The reconstruction-based methods are the mainstream in this task, which learn point-wise representation via unsupervised…

Machine Learning · Computer Science 2025-05-16 Mengxuan Li , Ke Liu , Hongyang Chen , Jiajun Bu , Hongwei Wang , Haishuai Wang