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Recent DNA pre-alignment filter designs employ DRAM for storing the reference genome and its associated meta-data. However, DRAM incurs increasingly high energy consumption background and refresh energy as devices scale. To overcome this…

Emerging Technologies · Computer Science 2022-12-27 Fazal Hameed , Asif Ali Khan , Sebastien Ollivier , Alex K. Jones , Jeronimo Castrillon

We propose and evaluate new techniques for compressing and speeding up dense matrix multiplications as found in the fully connected and recurrent layers of neural networks for embedded large vocabulary continuous speech recognition (LVCSR).…

Machine Learning · Computer Science 2018-02-07 Markus Kliegl , Siddharth Goyal , Kexin Zhao , Kavya Srinet , Mohammad Shoeybi

Accurate genome sequencing can improve our understanding of biology and the genetic basis of disease. The standard approach for generating DNA sequences from PacBio instruments relies on HMM-based models. Here, we introduce Distilled…

Motivation: Cellular Electron CryoTomography (CECT) enables 3D visualization of cellular organization at near-native state and in sub-molecular resolution, making it a powerful tool for analyzing structures of macromolecular complexes and…

Quantitative Methods · Quantitative Biology 2017-04-14 Min Xu , Xiaoqi Chai , Hariank Muthakana , Xiaodan Liang , Ge Yang , Tzviya Zeev-Ben-Mordehai , Eric Xing

Non-autoregressive models generate target words in a parallel way, which achieve a faster decoding speed but at the sacrifice of translation accuracy. To remedy a flawed translation by non-autoregressive models, a promising approach is to…

Computation and Language · Computer Science 2020-10-27 Pan Xie , Zhi Cui , Xiuyin Chen , Xiaohui Hu , Jianwei Cui , Bin Wang

Brain tumors show significant health challenges due to their potential to cause critical neurological functions. Early and accurate diagnosis is crucial for effective treatment. In this research, we propose ResLink, a novel deep learning…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Sumedha Arya , Nirmal Gaud

In the realm of X-ray spectral analysis, the true nature of spectra has remained elusive, as observed spectra have long been the outcome of convolution between instrumental response functions and intrinsic spectra. In this study, we employ…

Human evaluation of machine translation is in an arms race with translation model quality: as our models get better, our evaluation methods need to be improved to ensure that quality gains are not lost in evaluation noise. To this end, we…

Computation and Language · Computer Science 2025-10-29 Parker Riley , Daniel Deutsch , Mara Finkelstein , Colten DiIanni , Juraj Juraska , Markus Freitag

The Recurrent Neural Networks and their variants have shown promising performances in sequence modeling tasks such as Natural Language Processing. These models, however, turn out to be impractical and difficult to train when exposed to very…

Computer Vision and Pattern Recognition · Computer Science 2017-07-07 Yinchong Yang , Denis Krompass , Volker Tresp

The prevalent technique for DNA sequencing consists of two main steps: shotgun sequencing, where many randomly located fragments, called reads, are extracted from the overall sequence, followed by an assembly algorithm that aims to…

Genomics · Quantitative Biology 2016-01-28 Shirshendu Ganguly , Elchanan Mossel , Miklos Z. Racz

Transcriptomic foundation models pretrained with masked language modeling can achieve low pretraining loss yet produce poor cell representations for downstream tasks. We introduce whole-cell expression decoding (WCED), where models…

Most real-world datasets, and particularly those collected from physical systems, are full of noise, packet loss, and other imperfections. However, most specification mining, anomaly detection and other such algorithms assume, or even…

Machine Learning · Computer Science 2019-04-12 Ilia Sucholutsky , Apurva Narayan , Matthias Schonlau , Sebastian Fischmeister

Stroke order and velocity are helpful features in the fields of signature verification, handwriting recognition, and handwriting synthesis. Recovering these features from offline handwritten text is a challenging and well-studied problem.…

Computer Vision and Pattern Recognition · Computer Science 2021-05-26 Taylor Archibald , Mason Poggemann , Aaron Chan , Tony Martinez

The analysis of physiological processes over time are often given by spectrometric or gene expression profiles over time with only few time points but a large number of measured variables. The analysis of such temporal sequences is…

Machine Learning · Computer Science 2011-10-12 F. -M. Schleif , A. Gisbrecht , B. Hammer

Convolutional neural networks (CNN) have become a ubiquitous algorithm with growing applications in mobile and edge settings. We describe a compute-in-memory (CIM) technique called FPIRM using Racetrack Memory (RM) to accelerate CNNs for…

Emerging Technologies · Computer Science 2022-08-02 Sébastien Ollivier , Xinyi Zhang , Yue Tang , Chayanika Choudhuri , Jingtong Hu , Alex K. Jones

Genome annotation is an important issue in biology which has long been addressed with gene prediction methods and manual experiments requiring biological expertise. The expanding Next Generation Sequencing technologies and their enhanced…

Computation · Statistics 2013-07-02 Alice Cleynen , Michel Koskas , Emilie Lebarbier , Guillem Rigaill , Stephane Robin

Purpose: Although recent deep energy-based generative models (EBMs) have shown encouraging results in many image generation tasks, how to take advantage of the self-adversarial cogitation in deep EBMs to boost the performance of Magnetic…

Image and Video Processing · Electrical Eng. & Systems 2021-09-10 Yu Guan , Zongjiang Tu , Shanshan Wang , Qiegen Liu , Yuhao Wang , Dong Liang

We introduce a pattern mining framework that operates on semi-structured datasets and exploits the dichotomy between outcomes. Our approach takes advantage of constraint reasoning to find sequential patterns that occur frequently and…

Artificial Intelligence · Computer Science 2022-01-25 Xin Wang , Serdar Kadioglu

High-throughput RNA sequencing (RNA-seq) is now the standard method to determine differential gene expression. Identifying differentially expressed genes crucially depends on estimates of read count variability. These estimates are…

The recently introduced Tsetlin Machine (TM) has provided competitive pattern classification accuracy in several benchmarks, composing patterns with easy-to-interpret conjunctive clauses in propositional logic. In this paper, we go beyond…

Machine Learning · Computer Science 2019-06-25 K. Darshana Abeyrathna , Ole-Christoffer Granmo , Lei Jiao , Morten Goodwin
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